Polina Lishko
@physiologyiscool.bsky.social
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Physiologist/reproductive biologist/biophysicist. Ion channels are cool! Views are my own.
Happy to share our latest work on ion channels, published in
@natcomms.nature.com
. Want to know why testes are external & cool? Nature has evolved a precise system to ensure that sperm are primed for fertilization at the right time. Tour de force work by Dr. Dilip Swain and our team:
rdcu.be/eh9W7
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The essential calcium channel of sperm CatSper is temperature-gated
Nature Communications - Here they show that the essential sperm calcium channel CatSper is temperature-gated and reversibly inhibited by spermine. This discovery uncovers a key regulatory mechanism...
https://rdcu.be/eh9W7
6 months ago
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congratulations to
@alanbrownhms.bsky.social
lab, Rui Zhang lab
@ruizhangmt.bsky.social
and Qingwei Niu
@qingweiniu.bsky.social
!
add a skeleton here at some point
7 months ago
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Thrilled to share that our 4 years of hard work is finally published in Science Advances! 🚀🎉 Huge congratulations to the dream team: @monikahaoui, Citlalli Vergara, and our fantastic colleagues from the Marc Spehr group
www.science.org/doi/10.1126/...
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Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function
Progesterone and progestins activate Kir7.1 to control uterine excitability, offering insights for preterm birth therapy.
https://www.science.org/doi/10.1126/sciadv.adr5086
7 months ago
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