Aske Merrild
@amerrild.bsky.social
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Thanks for a great colab Marc!
add a skeleton here at some point
7 months ago
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>80 grams of engineered lasso peptide from 20 L E. Coli fermentation broth. This and more amazing results from Lassogen in preprint.
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8 months ago
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reposted by
Aske Merrild
Chekan Lab
8 months ago
We are excited to see our review published! In it, we explore the diversity of enzymatic strategies for installing aromatic side chain cross-links in RiPPs. If you like interesting chemistry and new enzyme reactions, be sure to check it out!
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Dr Katherine Duncan
11 months ago
I’m not entirely sure how these starter packs work… but I’ve created one for microbial natural products - hopefully it helps us connect!
go.bsky.app/72NeGsT
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Thomas Tørring
9 months ago
A Christmas present to all of the lasso peptide connoisseurs out there. The next chapter in our work is on triculamin is ready on bioRxiv. Great work by two incredibly talented graduate students
@amerrild.bsky.social
and
@tizianasvenningsen.bsky.social
.
www.biorxiv.org/content/10.1...
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Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin
Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene c...
https://www.biorxiv.org/content/10.1101/2024.12.20.629632v1
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