Notre institut recrute un ingénieur d'études (IE CNRS) - administrateur réseau en mobilité interne (NOEMIE). Merci de diffuser l'offre et de nous contacter pour toute information.

We are looking for candidates to apply for a Marie-Curie post-doctoral fellowship to work with us on epigenomic mechanisms of addiction in humans and rodent models. More details here, please spread the word: euraxess.ec.europa.eu/jobs/hosting...

Now available in its final, open access form: www.sciencedirect.com/science/arti...

Using a prospectively registered methodology, we included and reviewed 99 articles that manipulated the enzymes or characterized DNA methylation at candidate genes, or more recently genome-wide, including in the context of in utero or developmental exposure to drugs.

If interested in epigenomics & substance use disorders, take a look at our systematic review. We summarize current knowledge on DNA methylation & related enzymes across rodent models & drugs of abuse. Written w/ PhD student Margot Diringer & post-doc Mathieu Bruggeman www.biorxiv.org/content/10.1...

And don't hesitate to reach out if interested, in particular about mental health & neuroepigenetics. @incicnrs.bsky.social @agencerecherche.bsky.social @cnrs.fr @cnrsbiologie.bsky.social @inserm.fr @frm-officiel.bsky.social @fondationfyssen.bsky.social @procrystal.bsky.social

The Strasbourg (France) neuroscience community (NeuroStra) will offer 3 positions over the next 3 years for junior group leaders. Applicants should develop projects along 3 themes: --> Mental health --> Neuroepigenetics --> Nociception and Pain Spread the word! neurostra.unistra.fr/actualites/a...

Overall, we uncover a profound epigenetic sex divergence that mediates convergent biological dysregulation, and highlight opportunities for developing improved therapeutic strategies tailored to sex-specific mechanisms. www.biorxiv.org/content/10.1...

Happy to share our new preprint on opioid addiction! We profiled the multiomic consequences of chronic opioid exposure in male and female mouse brains, covering DNA methylation (using EMseq), 5 histone marks (Cut&Tag) & their transcriptional effects at bulk and cell-type-specific levels (vTRAP).

Nous appelons à la pérennisation des Haltes Soins Addictions (#HSA), avec @alexandracordebard.bsky.social @michelerubirola.bsky.social et Alexandre Feltz. À Paris et à Strasbourg, ces dispositifs essentiels de santé publique ont montré leur efficacité, confirmée par l'Inserm et l'IGAS.

Une belle conférence de Raoul Belzeaux pour en savoir plus sur les biomarqueurs en psychiatrie : www.youtube.com/live/U23xWQv...

Happy to share our latest work. We analyzed 3 omic layers, DNA methylation, micro-RNAs & the transcriptome, in patients with major depressive disorder & controls. Results showed that the performance of MDD prediction increased with the number of layers considered. www.thelancet.com/journals/ebi...

A team effort with many friends & colleagues @cnrs.bsky.social @incicnrs.bsky.social @cnrsbiologie.bsky.social @ap-hp.bsky.social @unistra.fr @univ-amu.fr @upcite.bsky.social @douglasresearch.bsky.social @univ-spn.bsky.social

New work from Tsvetan Serchov & colleagues: www.nature.com/articles/s41...

New work from Hervé Cadiou & colleagues: www.frontiersin.org/journals/mol...