when the test is significant but you forgot to check its effect size

Science aside, the typesetting of this preprint is beautiful. Apple-worthy

TIL you can create a multiqc compatible json/yml file and will just work out the box. docs.seqera.io/multiqc/cust...

Big fan of this hand drawn wholesome graphical abstract in today's @cp-cell.bsky.social 🐜

TIL that the Gendarmerie (military police) in France uses GendBuntu, a slight modification of ubuntu. And everything because they didn't want to move from Windows XP to vista 😅 en.wikipedia.org/wiki/GendBuntu

At Posit, we love @typst.app: ⚡ Make PDFs in milliseconds, not minutes ✨ The power of LaTeX with today's technologies ✍️ Modern typography (including emojis!) 🧠 Clear mental model So I'm thrilled to announce that we're now supporting its development: posit.co/blog/posit-a... #rstats

I started tgv to learn Rust and building it has been unbelievably fun! If you wanna pick up a super fast and fun programming language, tgv is open for contribution! There aren't many bioinformatics tools built entirely by the community. If tgv can become one, I'll be so psyched

*advertisement payed by a VC fund 😅

Never thought i would say this but R becoming more pythonic is a good thing 🙃 "R 4.5.0 introduces a new way to load objects from a package: use()"

American scientists aren't special. It's the institutions, and willingness to spend on research, that set them apart. Similarly invest here, and you will naturally attract the best talent from *everywhere*. www.politico.eu/article/euro...

Still life

23andMe to be sold off now, agree with @philippbayer.bsky.social it's likely there ll be a opt out mechanism for people that don't want their data distributed to pharma companies, but just glad I managed to delete my data on the site under GDPR, thanks EU 👌

this is really cool! 😎 obsidian is now free for all, simplicity over subscriptions

opening files in Obsidian, not sped up

🏔️🏔️🏔️ #flashes

Excited about the HTML experimental feature in @typst.app 0.13! 👏 typst.app/blog/2025/ty...

Roche Ripple Predictions My take on how Roche SBX will roil the sequencing landscape omicsomics.blogspot.com/2025/02/roch... 🧬🖥️

What a world we live in that the highest cost of a DNA sequencer is the computer+GPU instead of the "sequencing" itself, big benefits for SBX if AI bubble pops eventually "the biggest expense [...] is assuredly the compute onboard" by @omicsomics.bsky.social omicsomics.blogspot.com/2025/02/roch...

by @mnot.net on UK's demands to Apple 1. Comply 🔪 (seriously harm their core values and reputation) 2. Apple-xit 💸 (leave UK and lose 1.5Bn) 3. Decentralize 👥, would be cool to self-host your own iCloud data and would probably set the example to other companies www.mnot.net/blog/2025/02...

Placing European cities in a map is more complicated than it seems because regional definitions of metropolitan areas are not consistent. For instance, metro area in Barcelona is weird, includes heavily unpopulated areas in mountainous terrain where people cannot live, also airport and harbor

Great thread from @tommytang.bsky.social on why we need workflow managers in biology! Hard disagree on "[snakemake] feels natural for anyone familiar with Python scripting" though 😜

👀

i’m so tired but i’ve got obligations 😩

Europe PMC is a PubMed-like site, underrated IMO (the API is top notch), but as far as I know, it relies on PubMed for sourcing their data (some sort of mirror?) Wondering if there is a switch to make it independent somehow? Probably just depends on publishers sending their data there instead?

pro tip, every youtube channel has an associated RSS feed, add them to a rss reader and you can get a complete algorithm (and advertisement) free experience.

Longevity startups if humans were worms

Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n www.nature.com/articles/s41...

Register with @helloeacr.bsky.social Lisbon will be amazing! @eacrnews

it's nice that now new biotech are already publishing a processing bioinformatics pipeline for their new tool/service, integrating the molecular biology and standardizing outputs

Single Amino Acid Variant (SAAV) was not in my bingo card for this year (late 2024 actually). A new test for the adaptability of the VCF standard 😅 From Quantum-SI who are pushing their NGPS (Next Generation Protein Sequencing). www.biorxiv.org/content/10.1...

One of my favorite talks at the @nextflow.io summit was @kenibrewer.bsky.social's talk on how to NOT contribute to nf-core (using nf-core in your organization). He wrote a nice post on the @nf-co.re blog on building an nf-core style modules library for your organization seqera.io/blog/buildin...

#IEC 🔴 | Mor el científic Joan Guinovart, fundador de l’Institut de Recerca Biomèdica de Barcelona i membre de la Secció de Ciències Biològiques de l’IEC. Des de l’Institut d’Estudis Catalans volem donar el nostre més sentit condol a familiars i amics. ➡️ www.iec.cat/noticia/?id_...

also wild how consistent the PGS for ADHD is....

Reminds me of what Jeff Bezos said in a podcast "The advantage of compromise as a resolution mechanism is that it's low energy, but it doesn't lead to truth" You cannot really expect to "break the system" and maintain your position within such system at the same time.

Reading @natureportfolio.bsky.social these days....

while my experience with the Seqera AI hasn't been great (possible I asked impossible tasks) the vs-code integration is a MAJOR improvement. Really thankful for the upgrade! eg. hovering over process/workflow names you see its output channels directly, no switching to other files anymore 🚀

Can't wait for Bryan Johnson to add these into the "Blueprint" 😂

really cool story on the central "dogma" by @matthewcobb.bsky.social got me thinking why there isn't any case for the direct translation of DNA 🤔 open.substack.com/pub/cell/p/c...

Been self-hosting stirling-pdf for a while and it's a game changer. Mostly use it to OCR scanned documents. (needs docker desktop but the container is somewhat lightweight) github.com/Stirling-Too...

TIL i ve been pronouncing @typst.app wrong all this time (ty-P-st 😅) but really cool update, multi-column figures and line-numbers are must features to have! 👏 youtu.be/kSRZrFuUhCI?...

Despite a massive head start, BlueSky has now overtaken Threads in the US 👇

User verification here at @bsky.app is pretty neat, instead of relying on biased team of moderators (old twitter) or a subscription model (musk twitter), bsky uses domain name based verification, so if you trust the website, you trust the user.

I made a thing! I was playing around with the AT protocol and as a little experiment I made a website that visualises activity around Bluesky: nightsky.hctr.dev It listens to all new posts and shows them as little stars across a night sky 🌃 Every star is someone, somewhere, posting something

the starter pack for starter packs! 😂 really useful list @stephenturner.us 👌 blog.stephenturner.us/p/bluesky-fo...

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