Igor Fesenko
@igorfesenko.bsky.social
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Plant peptides, microproteins, computational biology
https://igorfesenko.github.io
pinned post!
Excited to share our publication on bacterial microproteome
www.cell.com/molecular-ce...
#microproteins
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The hidden bacterial microproteome
This study uncovers thousands of microprotein families encoded by intergenic small open reading frames (smORFs) in bacterial genomes and provides a publicly available resource featuring structural pre...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(25)00059-0
8 months ago
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reposted by
Igor Fesenko
Sofya Garushyants
26 days ago
hey bluesky š visa hurdles mean Iām looking for opportunities outside the US. Iām a computational biologist (bacterial + phage genomics, postdoc in Kooninās group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
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Happy to share our manuscript is now publishedš in @PPLplantarum A key finding: novel stress inducible peptides in bryophytes
dx.doi.org/10.1111/ppl....
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Comparative analysis of small secreted peptide signaling during defense response: insights from vascular and nonāvascular plants
Small secreted peptides (SSPs) play an important role in modulating immune responses in all land plants. However, the evolution of stress peptide signaling in different plant phyla remains poorly und...
http://dx.doi.org/10.1111/ppl.70147
7 months ago
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reposted by
Igor Fesenko
Molecular Cell
7 months ago
Read out latest issue here:
www.cell.com/molecular-ce...
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A fascinating paper demonstrating that proteasome-derived peptides can serve as a natural source of antimicrobial peptides
www.nature.com/articles/s41...
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Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature
Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...
https://www.nature.com/articles/s41586-025-08615-w
7 months ago
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reposted by
Igor Fesenko
Molecular Cell
8 months ago
Online Now: The hidden bacterial microproteome
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The hidden bacterial microproteome
This study uncovers thousands of microprotein families encoded by intergenic small open reading frames (smORFs) in bacterial genomes and provides a publicly available resource featuring structural predictions, predicted interactions between microproteinsā¦
http://dlvr.it/TJ4P13
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Excited to share our publication on bacterial microproteome
www.cell.com/molecular-ce...
#microproteins
loading . . .
The hidden bacterial microproteome
This study uncovers thousands of microprotein families encoded by intergenic small open reading frames (smORFs) in bacterial genomes and provides a publicly available resource featuring structural pre...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(25)00059-0
8 months ago
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reposted by
Igor Fesenko
Sebastiaan van Heesch
8 months ago
Hi everyone! We are still welcoming applicants for a computational postdoc position. If your profile fits our lab interests, please do reach out to me for more information or apply directly via the link below. I'm looking forward to reading your application!
www.academictransfer.com/en/jobs/3488...
add a skeleton here at some point
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reposted by
Igor Fesenko
Stephan Wenkel
9 months ago
Weāre looking for a postdoc in plant bioengineering to join an exciting interdisciplinary ERC project @UPSC! Work in a vibrant, international environment alongside top researchers, pushing the boundaries of plant science. Apply here:
shorturl.at/smdwD
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reposted by
Igor Fesenko
Ralf Reski
9 months ago
Very cool paper in Science: Simulating 500 million years of evolution with a language model
www.science.org/doi/10.1126/...
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Simulating 500 million years of evolution with a language model
More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins. Here we show that language models trained at scale on evolutionary data can gen...
https://www.science.org/doi/10.1126/science.ads0018
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reposted by
Igor Fesenko
Nature
9 months ago
Book review: The astonishing scientists who starved to protect plants during the Second World War
https://go.nature.com/4gSJOfk
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The astonishing scientists who starved to protect plants during the Second World War
The trials and tribulations of the worldās first seed bank reveal botanistsā enormous generosity and sacrifice during the siege of Leningrad.
https://go.nature.com/4gSJOfk
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reposted by
Igor Fesenko
Sebastiaan van Heesch
9 months ago
### Job alert, please repost! ### We're recruiting a computational postdoc in evolutionary genetics to help us understand whether recently emerged ncORFs and microproteins play roles in childhood brain cancers. Will you become part of our team?
werkenbijprinsesmaximacentrum.nl/en/vacancy/p...
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Postdoc computational evolutionary genomics of non-canonical ORFs and microproteins in childhood brain cancer - Werken bij Prinses Maxima Centrum
Background Over recent years, the van Heesch lab has discovered thousands of new ānon-canonicalā open reading frames (ncORFs) translated from regions of the genome believed not to code for protein. Ma...
https://werkenbijprinsesmaximacentrum.nl/en/vacancy/postdoc-computational-evolutionary-genomics-of-non-canonical-orfs-and-microproteins-in-childhood-brain-cancer-2/
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Happy New Year!āļø
9 months ago
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reposted by
Igor Fesenko
John Prensner
11 months ago
Do you want to go further with your proteomics? Looking for something new in cancer? Check out microproteins! Thanks to
@science.org
for featuring this work, in collaboration with
@sebastiaanvheesch.bsky.social
,
#HUPO
,
@gencodegenes.bsky.social
www.science.org/content/arti...
š microprotein 𧬠š»
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āDark proteomeā survey reveals thousands of new human genes
Database confirms that overlooked segments of the genome code for a multitude of tiny proteins
https://www.science.org/content/article/dark-proteome-survey-reveals-thousands-new-human-genes
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reposted by
Igor Fesenko
Anne-Ruxandra Carvunis
11 months ago
Small proteins, mighty potential! Whether you're an afficionado or just interested in diving into the world of
#microproteins
, join us for a Keystone meeting February 2025 in Beverly MA:
www.keystonesymposia.org/conferences/...
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Microproteins: from Discovery to Applications | Keystone Symposia
Join us at the Keystone Symposia on Microproteins: from Discovery to Applications, February 2025, in Beverly, with field leaders!
https://www.keystonesymposia.org/conferences/conference-listing/meeting/pricing/t22025
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