Xihong Lin
@xihonglin.bsky.social
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Professor of Biostatistics and Statistics, Harvard U, Genomics, ML, Health
reposted by
Xihong Lin
Nature Computational Science
8 months ago
An accompanying Research Briefing is also available for the paper!
www.nature.com/articles/s43...
#stats
🖥️ 🧬 🔓https://rdcu.be/d82FR
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MultiSTAAR delivers multi-trait rare variant analysis of biobank-scale sequencing data - Nature Computational Science
Identifying pleiotropic associations for rare variants in multi-ethnic biobank-scale whole-genome sequencing data poses considerable challenges. This study introduced MultiSTAAR as a scalable and robu...
https://www.nature.com/articles/s43588-025-00766-0?utm_source=bluesky&utm_medium=social&utm_campaign=natcomputsci
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reposted by
Xihong Lin
Nature Computational Science
8 months ago
📢Out now!
@xihonglin.bsky.social
,
@pnatarajanmd.bsky.social
and colleagues present a framework for functionally-informed multi-trait rare variant analysis of biobank-scale sequencing studies.
www.nature.com/articles/s43...
#stats
🖥️ 🧬 🔓https://rdcu.be/d82Fx
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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies - Nature Computational Science
MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits an...
https://www.nature.com/articles/s43588-024-00764-8?utm_source=bluesky&utm_medium=social&utm_campaign=natcomputsci
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