📰 Hot off the press from the Xue & Sontheimer labs 🧬: Prime assembly enables precise genomic insertions up to 11 kb in cells, providing a universal strategy to correct many pathogenic mutations within a gene. Read it @nature.com: buff.ly/dYn0NjS @UMassChan.bsky.social @eriksontheimer.bsky.social

Site-specific, multi-kilobase insertions and over-writes in mammalian cells, without DSBs, HDR, recombinases, integrases, transposases, or active cell cycling? Using fully or predominantly single-stranded DNA donors? 1/15

For the 2026 primary elections, NPR has collected deadlines and information on how to register to vote — online, in person or by mail — in every U.S. state and territory.

Registration for CRISPR 2026 is now open: web.cvent.com/event/ac20b6.... Early-bird price discounts are available until the end of February.

The CRISPR 2026 website is up! Links for abstract submission and registration will be available February 1st: web.cvent.com/event/ac20b6...

SCOTUS: considering race as one factor in a college applicant's file is blatantly unconstitutional ALSO SCOTUS: considering race as one factor in targeting whom to detain and deport is cool cool cool

Hot off the press from the RTI: Prime assembly with linear DNA donors enables large genomic insertions pubmed.ncbi.nlm.nih.gov/40667017/?ut... #RNA #RNATherapeutics

Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription. www.cell.com/cell/fulltex... Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.

Fun news: I'm starting my research group at @rti-umasschan.bsky.social as the inaugural Maraganore Fellow! Our lab will focus on the RNA sequence-structure-function relationship in the cellular environment. Visit our website to explore open positions: schaerfenlab.com #RNA #Hiring #PostbacJobs

On Thursday, Anastasia Khvorova, PhD, received the 2025 Else Kröner Fresenius Prize for Medical Research, a $2.7 million award, for her pioneering work in the field of RNA-based therapies. 📸: Else Kröner-Fresenius-Stiftung #EKFprize25 #EKFS #RNA @ekfstiftung.bsky.social @rti-umasschan.bsky.social

"The consolidation/RIF plan pulls power away from scientists and puts it in the hands of political employees. It sets up Trump and Musk to kill NIH as an evidence-based science funder. We must stop this plan." New contributed post on our blog: Please read. It describes Orban and authoritarianism. 🧪

Pressing question of the day: when will @epigenetichulk start smashing puny genomes on Bluesky?