Abid Hussain
@amh10.bsky.social
📤 989
📥 1260
📝 356
Medical Microbiologist & Clinical Services Director @UKHSA BPHL. All posts my own.
#QI
#ClinGov
⚠️ Non professional thread ⚠️ My 20 most important albums:
about 2 months ago
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reposted by
Abid Hussain
Willem van Schaik
about 2 months ago
That was a great meeting, I am a very happy, but slightly tired, man. Check
@amh10.bsky.social
's timeline for a great summary of
#TARGetAMR26
add a skeleton here at some point
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reposted by
Abid Hussain
Kate Baker
about 2 months ago
Preprint found here:
www.medrxiv.org/content/10.6...
👀
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Evaluating Genomic Surveillance Methods for Shigella sonnei in a High-Income Setting
Shigella sonnei is a human-adapted enteric pathogen with a very low infectious dose and increasing antimicrobial resistance. In high-income settings, transmission is multimodal including sporadic case...
https://www.medrxiv.org/content/10.64898/2026.05.08.26352707v1
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reposted by
Abid Hussain
TARGetAMR
about 2 months ago
🎉 That’s a wrap on
#TARGetAMR26
! Huge thanks to our amazing attendees, inspiring speakers, brilliant sponsors, and our fantastic venue, The Studio, for hosting us! 💙 🙌 Here’s to building the future of AMR Genomics together!
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@katholt.bsky.social
gives the keynote
@target-amr.bsky.social
speech on interpretive standards for AMR genotypes
#TARGetAMR26
about 2 months ago
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Charles Wei tells us about Shigella sonnei sequencing and the role in MSM contact tracing
@target-amr.bsky.social
#TARGetAMR26
www.gen.cam.ac.uk/directory/gr...
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Postgraduate Students | Department of Genetics
https://www.gen.cam.ac.uk/directory/graduate-students
about 2 months ago
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@jgarciaiglesias.bsky.social
Interesting discussion around what genomics we need in AMR - policymakers and communities don't know what they need so there needs to be live discussion around surveillance
@target-amr.bsky.social
#TARGetAMR26
about 2 months ago
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reposted by
Abid Hussain
TARGetAMR
about 2 months ago
🌟Great start to
#TARGetAMR26
! 🎙️Today we heard an inspiring keynote, insightful talks and fantastic discussions on AMR genomics Plus our Co-Directors
@wvschaik.bsky.social
@ksbakes.bsky.social
unveiled: 🚀Launch of our Flexible Funding Initiative 📚Debut of the TARGetAMR comic ⌛️We can't wait for Day 2!
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reposted by
Abid Hussain
Willem van Schaik
about 2 months ago
Super-excited to be organising the first in-person meeting of the
@target-amr.bsky.social
network today and tomorrow. We will be launching an initiative for pump-priming and an amazing comic by Eddie Ross on AMR Genomics
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reposted by
Abid Hussain
Claas Kirchhelle
6 months ago
Hot off the press in
@lancetmicrobe.bsky.social
! In (Un)intended Consequences, we conduct a
#socsci
stocktake of 10 years of research on
#AMR
interventions, highlight the need for more contextual
#antimicrobial
governance & make recommendations
#GAP'26
!
#IDSky
www.sciencedirect.com/science/arti...
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(Un)intended consequences: a social sciences stocktake of a decade of Global Action Plan-inspired antimicrobial governance
Antimicrobial resistance (AMR) remains a major global health threat. Despite increasing international attention, AMR governance has often neglected so…
https://www.sciencedirect.com/science/article/pii/S2666524725002435
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reposted by
Abid Hussain
Willem van Schaik
about 2 months ago
Today we are launching the
@target-amr.bsky.social
flexible funding initiative to pump prime new research across disciplines in the broad field of AMR genomics. Introduction by
@ksbakes.bsky.social
at
#TARGetAMR26
Flexible Funding – TargetAMR
share.google/bWYYdQUo8azy...
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Customised genome reporting in UK healthcare for AMR pathogens with
@cmcrodrigues.bsky.social
@ukhsa.bsky.social
#TARGetAMR26
about 2 months ago
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@clarebarker.bsky.social
explains the rtole of genomics in GI infection at the
@ukhsa.bsky.social
- this is a therapeutic challenge!
#TARGetAMR2026
. Reviewing
#cholera
first.....
about 2 months ago
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@kirchhelle.bsky.social
kicks off
@target-amr.bsky.social
discussing AMR opportunities and challenges. I would like to know what the world learnt from the
#pandemic
that can be translated to
#AMR
, especially as this is not a vaccine-preventable problem?
#TARGetAMR26
about 2 months ago
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Here we go
@target-amr.bsky.social
about 2 months ago
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On my way to
@target-amr.bsky.social
conference in Birmingham. See you there
@wvschaik.bsky.social
@imibirmingham.bsky.social
about 2 months ago
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Many talented colleagues and excellent speakers at the
@target-amr.bsky.social
conference tomorrow
@wvschaik.bsky.social
#TARGetAMR26
. I'll post some thoughts here, flying the flag for
@ukhsa.bsky.social
and
@imibirmingham.bsky.social
www.targetamr.org.uk/hdrevents/ta...
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TARGetAMR Conference 2026 14th-15th May 26 – TargetAMR
https://www.targetamr.org.uk/hdrevents/targetamr-annual-conference-2026-14th-15th-may-26/
about 2 months ago
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Your mobile phone is a vector in HCAI transmission:
journals.sagepub.com/doi/10.1177/...
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Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
https://journals.sagepub.com/doi/10.1177/17571774261431982
about 2 months ago
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Candida UTI? The only azole available (if sensitive) is fluconazole. Why?
about 2 months ago
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Pearl of the week: Compare and contrast DILI in flucloxacillin vs cefazolin. They key thing is that a *single* dose of cefazolin can cause LFT derrangment.
about 2 months ago
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reposted by
Abid Hussain
Antibiotic Steward 🅱️C🆔🅿️🌟
3 months ago
🆕💥🟢LIPS RCT Protocol: LInezolid Plus Standard of care 12 Swiss hospitals Linezolid in addition to standard antibiotic treatment for Staphylococcus aureus bacteraemia More combo /SA Bactremia Clinda failed in SNAP,will LZD make it? More combo from SNAP
#idsky
bmjopen.bmj.com/content/16/4...
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The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe
www.thelancet.com/journals/lan...
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The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study
Independent acquisition of plasmids and homoplastic mutations conferring antimicrobial resistance have occurred repeatedly in multiple lineages of S Typhi, predominantly arising in south Asia before s...
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247%2822%2900093-3/fulltext
4 months ago
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Checkout this article I found at PLOS:
dx.plos.org/10.1371/jour...
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Ionizing Radiation Changes the Electronic Properties of Melanin and Enhances the Growth of Melanized Fungi
BackgroundMelanin pigments are ubiquitous in nature. Melanized microorganisms are often the dominating species in certain extreme environments, such as soils contaminated with radionuclides, suggestin...
https://dx.plos.org/10.1371/journal.pone.0000457
5 months ago
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Genomic and physiological signatures of adaptation in pathogenic fungi
doi.org/10.1038/s414...
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Genomic and physiological signatures of adaptation in pathogenic fungi - Nature Communications
Emerging fungal pathogens have detrimental impacts on crops, animals, and humans, however little is known about their transition to a pathogenic lifestyle. This study demonstrates that the transition ...
https://doi.org/10.1038/s41467-026-68330-6
5 months ago
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Enterococcal cytolysin, add to pathogenicity: Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage | PNAS
share.google/fiK7cIw373xC...
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Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage | PNAS
The fungus Candida albicans and the Gram-positive bacterium Enterococcus faecalis share mucosal niches in the human body. As opportunistic pathogen...
https://share.google/fiK7cIw373xCpLupk
5 months ago
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An interesting role for faecal transplants
rdcu.be/e1JKV
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Fecal microbiota transplantation plus pembrolizumab and axitinib in metastatic renal cell carcinoma: the randomized phase 2 TACITO trial
Nature Medicine - In a double-blind, placebo-controlled phase 2 trial in patients with metastatic renal cell carcinoma treated with anti-PD-1 plus a VEGFR tyrosine kinase inhibitor, donor fecal...
https://rdcu.be/e1JKV
5 months ago
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Bradyzoite subtypes rule the crossroads of Toxoplasma development
rdcu.be/e1zCI
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Bradyzoite subtypes rule the crossroads of Toxoplasma development
Nature Communications - The authors investigate the heterogeneity of Toxoplasma bradyzoites prior to recrudescence. Tissue cysts from infected mice harbor multiple bradyzoite subtypes with distinct...
https://rdcu.be/e1zCI
5 months ago
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reposted by
Abid Hussain
ESCMID
6 months ago
This online course presents the current knowledge on PK/PD of common antibiotics & antivirals, setting clinical breakpoints, individualised dosing & TDM. Innovative approaches for drug development also highlighted. More:
https://ow.ly/mszr50XXS9H
⏰Register by 09 March 2026!
#IDSky
#clinmicro
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Antibiotic Therapy for Uncomplicated Acute Appendicitis:
jamanetwork.com/journals/jam...
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Antibiotic Therapy for Uncomplicated Acute Appendicitis
This observational follow-up of patients in the Appendicitis Acuta multicenter randomized clinical trial conducted in Finland assesses the 10-year appendicitis recurrence and appendectomy rate in adul...
https://jamanetwork.com/journals/jama/fullarticle/2844116?utm_source=bluesky&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=012126
6 months ago
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www.linkedin.com/posts/uk-hea...
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ESPAUR Abstracts Published: Perspectives on a valuable resource for tackling antimicrobial resistance | UK Health Security Agency
UKHSA's English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) abstracts are now available in a dedicated journal supplement, making this vital data more accessible to re...
https://www.linkedin.com/posts/uk-health-security-agency_ukhsas-english-surveillance-programme-for-activity-7418968492722282496-NGiE?utm_source=share&utm_medium=member_android&rcm=ACoAABHmmiQBJmxFv0JcVLBgc-ThpurUovAXrb8
6 months ago
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Albumin orchestrates a natural host defence mechanism against mucormycosis | Nature
share.google/gKuxL49O8Fsj...
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Albumin orchestrates a natural host defence mechanism against mucormycosis - Nature
Albumin selectively inhibits Mucorales growth through the release of bound free fatty acids.
https://share.google/gKuxL49O8FsjdyXx2
6 months ago
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The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation - Clinical Microbiology and Infection
www.clinicalmicrobiologyandinfection.org/article/S119...
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The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation
The emergence of extensively drug-resistant Enterobacterales, particularly carbapenemase-producing Klebsiella pneumoniae, poses a serious global health threat. Cefiderocol (FDC), a sideromycin antibio...
https://www.clinicalmicrobiologyandinfection.org/article/S1198-743X%2825%2900619-6/fulltext
7 months ago
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The songs I listened to most this year.
#SpotifyWrapped
www.spotify.com/wrapped-shar...
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My Top Songs of 2025
Spotify
https://www.spotify.com/wrapped-share/2c4e15af593a43d389ee46d53d933ba9?si=ah_wKQryRdyo0AweIIURCA&feature=wrapped&destination=datastories&lang=en
7 months ago
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Disenchanted took my top spot this year. More in my
#SpotifyWrapped
www.spotify.com/wrapped-shar...
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My Top Song of 2025
Spotify
https://www.spotify.com/wrapped-share/2034dc5b1a0c4324918774a40b4450ef?si=XzVTpEdSRQyTpIYPPo_uXw&feature=wrapped&destination=datastories&lang=en
7 months ago
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reposted by
Abid Hussain
JAC-AMR
7 months ago
In high-risk febrile neutropenic patients, an AMS bundle safely reduced broad-spectrum antibiotic use, shifting from MEM to CAZ and shortening treatment duration A meaningful step forward in
#AntimicrobialStewardship
in high-risk populations
doi.org/10.1093/jaca...
#JACAMRNews
#IDSky
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Impact of an antimicrobial stewardship bundle on the outcome of high-risk neutropenic patients with fever: a pre-post study
AbstractBackground. Rapid antibiotic initiation is essential for managing potential infections following chemotherapy-induced neutropenia. However, excessi
https://doi.org/10.1093/jacamr/dlaf191
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The key question is, where does Emblaveo fit when chosing empirical therapy?https://link.springer.com/article/10.1007/s40265-025-02258-x
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Aztreonam-Avibactam: A Review in the Treatment of Serious Bacterial Infections Caused by Aerobic Gram-Negative Organisms - Drugs
Aztreonam-avibactam (Emblaveo™), a fixed-dose combination of the monobactam antibacterial agent aztreonam and the broad-spectrum β-lactamase inhibitor avibactam, has been developed as a treatment, adm...
https://link.springer.com/article/10.1007/s40265-025-02258-x
8 months ago
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My thoughts on AMS and where we are heading:
www.linkedin.com/pulse/stewar...
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Stewardship 2.0: Harnessing Data, Tech, and Teamwork to Save Antibiotics
When we think about the rise of antibiotic-resistant superbugs, our minds typically go to one place: the unwell patient. The prevailing wisdom is that antimicrobial resistance (AMR) is a direct conseq...
https://www.linkedin.com/pulse/stewardship-20-harnessing-data-tech-teamwork-save-abid-hussain-2ryqe
9 months ago
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Resolving a NICU outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction
www.journalofhospitalinfection.com/article/S019...
@alanmcn1.bsky.social
@wvschaik.bsky.social
@jessicamablair.bsky.social
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Resolving a neonatal intensive care unit outbreak of meticillin-resistant Staphylococcus aureus to the single-nucleotide variant level using Oxford Nanopore simplex reads and HERRO error correction
Our laboratory began prospective genomic surveillance for healthcare-associated organisms in 2022 using Oxford Nanopore Technologies (ONT) as a standalone platform. While effective for early outbreak ...
https://www.journalofhospitalinfection.com/article/S0195-6701%2825%2900177-X/fulltext
10 months ago
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Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment
doi.org/10.1177/2049...
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Advancements in urinary tract infections: understanding, prevention, diagnosis, and treatment - Bhaskar K. Somani, 2025
https://doi.org/10.1177/20499361251376457
10 months ago
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Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better! - More studies needed
www.clinicalmicrobiologyandinfection.org/article/S119...
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Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better!
Each day thousands of patients are hospitalized worldwide with Community-Acquired Pneumonia (CAP), either radiologically confirmed or presumed based on clinical symptoms only, and each day physicians ...
https://www.clinicalmicrobiologyandinfection.org/article/S1198-743X%2825%2900427-6/fulltext
10 months ago
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reposted by
Abid Hussain
Alan McNally
10 months ago
Read this properly now and it really is a staggeringly beautiful study. And super important. Opens a new avenue of research I reckon. One of my papers of the year.
add a skeleton here at some point
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Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024 url:
academic.oup.com/cid/article/...
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Cardiac Manifestations of Mycoplasma pneumoniae Infections: A Cohort Study 2007–2024
A 17-year cohort shows higher incidence of cardiac involvement than previously reported in patients admitted with Mycoplasma pneumoniae infections that may
https://academic.oup.com/cid/article/doi/10.1093/cid/ciaf453/8244960
10 months ago
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Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia - Journal of Infection and Chemotherapy
www.jiac-j.com/article/S134...
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Teicoplanin total trough concentration and adverse effects in patients with hypoalbuminemia
The association between Teicoplanin (TEIC) total trough concentration (Cmin) and adverse effects (hepatotoxicity, nephrotoxicity, and thrombocytopenia) in patients with hypoalbuminemia remains poorly ...
https://www.jiac-j.com/article/S1341-321X%2825%2900204-1/fulltext
10 months ago
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The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study - The Lancet Microbe
www.thelancet.com/journals/lan...
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The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study
Independent acquisition of plasmids and homoplastic mutations conferring antimicrobial resistance have occurred repeatedly in multiple lineages of S Typhi, predominantly arising in south Asia before s...
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247%2822%2900093-3/fulltext
12 months ago
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www.nature.com/articles/s41...
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Brief antibiotic use drives human gut bacteria towards low-cost resistance - Nature
Brief ciprofloxacin exposure in humans drives antibiotic resistance evolution in gut bacteria through selective sweeps, particularly involving DNA gyrase mutations, which persist long after exposure a...
https://www.nature.com/articles/s41586-025-08781-x
about 1 year ago
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reposted by
Abid Hussain
Penta - Child Health Research
about 1 year ago
To tackle antibiotic resistance (#AMR) in newborns, especially premature babies in
#NICUs
, researchers explored the best trial design for studying
#IPC
. See what this simulation study, based on
#NeoIPC
data and presented at
#ESCMIDGlobal
, suggests 👇 View poster:
neoipc.org/wp-content/u...
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Using R coding
#ESCMID2025
about 1 year ago
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Using R!
#ESCMID2025
about 1 year ago
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Candida diagnostics in endovascular infections. Is
@brukercorporation.bsky.social
#MALDI
better for Candida pararugosa?
#ESCMID2025
about 1 year ago
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