We are happy to present a new paper on gastric tumour evolution in response to peri-operative chemotherapy. www.biorxiv.org/content/10.1... 🧵 1/6

New work from the lab trying to wrap our heads around the massive complexity of the human transcriptome revealed by long-read RNA-seq! Fun collab with Gloria Sheynkman. www.biorxiv.org/content/10.1...

🚨 Our GW paper is out in Nature Methods!🥲 GW is a fast genomics browser (up to 100x faster!) github.com/kcleal/gw Also, just released a Python interface for GW github.com/kcleal/gwplot 📝 nature.com/articles/s4159…#Genomicsc#Bioinformaticscs

A really useful resource

@adbeggs.bsky.social Hi Andrew. Fantastic talk today at the WCRC conference! It was very inspiring 👏

🧬🖥️ Just released Dysgu v1.8 which now supports phasing of structural variants when using long reads. Makes SV calling much more sensitive - see PacBio benchmark 👉 github.com/kcleal/SV_Be... dysgu repo github.com/kcleal/dysgu...

🧬🖥️ Sharing an update to my SV benchmark repo. More callers have been added for the CMRG/GIAB benchmarks. github.com/kcleal/SV_Be.... Also now uses #Nextflow and tests the newest #PacBio Vega data, along with #ONT kit14. Results are on the GitHub page 👉

Hi all. Just released a fast library (C++/Rust/Python) for performing interval intersections. Uses a novel superset-index that tends to be faster than current libs, and also has a SIMD accelerated counting algorithm 👇 github.com/kcleal/super...

I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics) go.bsky.app/TRWCnZs

BioNumpy looks really good, looking forward to giving this a try www.nature.com/articles/s41...

I created a genomics+bioinformatics starter pack. If I left you off, *please* reply and I'll add you! go.bsky.app/B5YYBfq

Hello world! This looks promising