Leo Speidel
@leospeidel.bsky.social
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📥 157
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Statistical and Population Genetics | RIKEN, iTHEMS (Japan) | 🇯🇵🇩🇪🇬🇧 |
New preprint led by Hrushikesh Loya, me, and Simon Myers where we introduce GhostBuster!
www.biorxiv.org/content/10.6...
The idea is to find all the different ways a target individual relates to reference groups in genealogies, to "bust the ghosts" in our ancestry.
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https://www.biorxiv.org/content/10.64898/2026.04.17.719197v1
6 days ago
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Very honoured and I owe a lot to all my mentors and colleagues, thank you!
add a skeleton here at some point
6 days ago
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New ad for an independent postdoc in mathematics/statistics/machine learning for Biology in my institute at RIKEN (not my lab), ranging from 3 to 7 years. Our institute is entirely English-run, and a good mix of expertise on maths/physics/stats/bio!
www.riken.jp/en/careers/r...
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Seeking a few Senior Research Scientists, Research Scientists, Postdoctoral Researchers at Division of Fundamental Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical...
https://www.riken.jp/en/careers/researchers/20251017_1/index.html
6 months ago
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Postdoc position in my group in Tokyo! Please get in touch if you are interested. And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab. Job Ad:
www.riken.jp/en/careers/r...
Lab page:
speidellab.github.io
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Seeking a few Postdoctoral Researchers at Mathematical Genomics RIKEN ECL Research Unit (25-695)
https://www.riken.jp/en/careers/researchers/20250620_1/index.html
10 months ago
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reposted by
Leo Speidel
Anders Bergström
11 months ago
A 4-year postdoc position in population genomics is available in my group at the University of East Anglia, to work on a project sequencing a thousand fox genomes across rural and urban environments in the UK.
vacancies.uea.ac.uk/vacancies/15...
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Senior Research Associate in Population Genomics (RA2327) in University of East Anglia | UEA
View details and apply for this Senior Research Associate in Population Genomics (RA2327) vacancy in University of East Anglia. Faculty of Science School of Biological Sciences Senior Research A...
https://vacancies.uea.ac.uk/vacancies/1593/senior-research-associate-in-population-genomics-ra2327.html
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Leo Speidel
Arun Durvasula
11 months ago
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv:
arxiv.org/abs/2506.00692
(based on last year's
@official-smbe.bsky.social
symposium)
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Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...
https://arxiv.org/abs/2506.00692
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Leo Speidel
HAAM-community
11 months ago
🧵1/n ✨🔮✨ Meet (y)our instructors of this year's
#HAAMsummerschool
👇
#aDNA
#course
#humanpopgen
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Leo Speidel
Jonathan Pritchard
11 months ago
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
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Leo Speidel
Lucy van Dorp
11 months ago
Our
@ucl.ac.uk
@crick.ac.uk
work, out this week in
@science.org
, traces a genetic time series of bacterial infections to reveal when and how Borrelia recurrentis jumped from ticks to humans—via our body lice.
www.science.org/doi/10.1126/...
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Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever
Several bacterial pathogens have transitioned from tick-borne to louse-borne transmission, which often involves genome reduction and increasing virulence. However, the timing of such transitions remai...
https://www.science.org/doi/10.1126/science.adr2147
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Leo Speidel
Tábita Hünemeier
12 months ago
Our new paper is out in
@science.org
! By exploring the rich genetic diversity of Brazil, we show how fine-scale genomic analyses reveal that this diversity, rooted in Indigenous ancestry and centuries of complex demographic history, plays a key role in population health.
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Leo Speidel
Aylwyn Scally
about 1 year ago
Our paper on ancient human population structure is now published. We find that the ancestors of modern humans lived in multiple populations during the period when Homo sapiens evolved in Africa.
www.nature.com/articles/s41...
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A structured coalescent model reveals deep ancestral structure shared by all modern humans - Nature Genetics
The cobraa model extends the pairwise sequentially Markovian coalescent to identify structured population history by examination of the model transition matrix. Applied to human polymorphism data, cob...
https://www.nature.com/articles/s41588-025-02117-1
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Leo Speidel
Aylwyn Scally
about 1 year ago
We are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here.
www.jobs.cam.ac.uk/job/50414/
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Assistant/Associate Professor in Computational Biology - Job Opportunities - University of Cambridge
Assistant/Associate Professor in Computational Biology in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.
https://www.jobs.cam.ac.uk/job/50414/
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Leo Speidel
Matthew Hahn
about 1 year ago
Octo-squid-nautiloid sex chromosomes!
www.sciencedirect.com/science/arti...
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Cephalopod sex determination and its ancient evolutionary origin
Octopuses, squids, and cuttlefishes—the coleoid cephalopods—are a remarkable branch in the tree of life whose members exhibit a repertoire of sophisti…
https://www.sciencedirect.com/science/article/pii/S0960982225000053
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Leo Speidel
Kevin Daly
about 1 year ago
Thread and open access version to come- Ancient genomics and the origin, dispersal, and development of domestic sheep | Science
search.app/gtSKYHF5HqRa...
#adna
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Ancient genomics and the origin, dispersal, and development of domestic sheep
The origins and prehistory of domestic sheep (Ovis aries) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled from across Eurasia. Ge...
https://search.app/gtSKYHF5HqRarFCC6
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Leo Speidel
Jonathan Pritchard
about 1 year ago
I posted a couple days ago about our new paper on building causal graphs from genetic associations + Perturb-seq. Here I want to expand on the value of using DIRECTIONAL information contained in LoF burden tests.🧵 [work led by
@minetoota.bsky.social
]
bsky.app/profile/jkpr...
add a skeleton here at some point
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reposted by
Leo Speidel
Society for Molecular Biology and Evolution
about 1 year ago
📢📢📢
#SMBE2025
Abstract Submission EXTENDED to Saturday, February 15, 2025 We also invite you to register at
www.smbe2025.org
@SMBEmeetings
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Leo Speidel
about 1 year ago
Excited to share our preprint "A putative ecocline in Klebsiella pneumoniae" and super-interested to get your feedback. Really want to use the hive mind to get to the bottom of this phenomenon ASAP.
www.biorxiv.org/content/10.1...
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A putative ecocline in Klebsiella pneumoniae
Are quantitative traits important for bacteriology? The quantitative trait models used in animal and plant genetics assume that the trait takes continuous values and is influenced by many variants cir...
https://www.biorxiv.org/content/10.1101/2025.01.20.633859v2
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My bluesky debut! One week to the submission deadline for SMBE 2025, Beijing 20-24 July
smbe2025.scimeeting.cn
@anaignatieva.bsky.social
and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.
over 1 year ago
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