Freshly in press from the Henneke lab: LDL cholesterol is required for macrophages to form multinucleated giant cells after BCG exposure. Congrats to Dr. Philipp Merck for an impressive MD thesis! And congrats to the team, so proud to have been part of this. www.nature.com/articles/s41...

Online now: Sensory neurons shape local macrophage identity via TGF-β signaling

Excited to share our new paper on pediatric non-tuberculous mycobacterial (NTM) lymphadenitis. Using advanced histology we identify patterns associated with favorable outcomes. We hope this helps refine NTM care. Open access @Frontiers in Immunology: www.frontiersin.org/journals/imm...

Follow-up study: After our recent paper on PIMS-TS/MIS-C across pandemic waves, we’re now reporting on intermediate-term outcomes. Read the paper @Journal of Pediatrics: www.sciencedirect.com/science/arti...

Mycobacterial infection uncovers plasticity of Kupffer cells https://www.biorxiv.org/content/10.1101/2025.02.07.636999v1

Sensory neurons shape macrophage identity via TGF-β signalling https://www.biorxiv.org/content/10.1101/2025.02.06.635770v1

Excited to announce a new preprint from the Henneke Lab: "Tissue imprinting defines functional mosaic of dermal macrophages" It explores how dermal macrophages adapt and specialize within their microenvironment during infections. Feedback and discussions welcome! www.biorxiv.org/content/10.1...

Join the cutting-edge discussions at the International Symposium on Perinatal and Early Life Immunity, April 9-12 2025, Freiburg, Germany. www.perinatal-immunity.de/en/symposium2025 Late-breaking abstracts still accepted!

In press @Journal of Pediatrics Clinical insights from the German PIMS-TS cohort: A comprehensive analysis of an all-but-extinct pediatric inflammatory disease. www.jpeds.com/article/S002...