Excited to share our new review in Trends in Neuroscience with Gouki Okazawa @gouki-okazawa.bsky.social : "The 'neat' and 'messy' in task-dependent neural geometry and computation" where we reviewed what we know about the 'task-manager' in the brain. A thread 👇

New review with Cheng Xue at U Chicago @cxue.bsky.social in Trends [email protected]! We discuss the neural geometry of task-dependent computation: disentangled encoding, RNN modeling, switch cost, etc. www.cell.com/trends/neuro...

The ‘neat’ and ‘messy’ in task-dependent neural geometry and computation by Cheng Xue @cxue.bsky.social & Gouki Okazawa @gouki-okazawa.bsky.social www.cell.com/trends/neuro...

Made an AI-curated primate ephys literature database covering ~10000 papers with recording brain regions and target functions. Maybe useful for something. okazawagouki.github.io/NHPLit/repor...

From the top of my head, here some recent ones: "Two views on the cognitive brain" by @johnwkrakauer.bsky.social, @dlbarack.bsky.social "Reconstructing computational system dynamics from neural data with recurrent neural networks" by @durstewitzlab.bsky.social et al 1/3

The basal ganglia output is often framed as a motor gate: corticostriatal circuits select an action, then GPi/SNr-thalamus helps release it. In humans, we find this same pathway carries cognitive variables embedded in movement signals—and even produces learning-relevant signals after feedback. 1/10

Final paper of my PhD 🤗 www.nature.com/articles/s44... There is growing interest in how cognitive control may improve value-based decision making. However, we find that a recent paper overestimated the role of control in their task, leading to erroneous interpretations of dACC recordings.

A mesoscale optogenetics system for precise and robust stimulation of the primate cortex www.cell.com/neuron/abstr...

Task-similarity dependent reconfiguration of compositional modules and geometry in frontal cortex www.biorxiv.org/content/10.1...

Population-level temporal decoding and dynamical structure in frontostriatal circuits during decision making www.biorxiv.org/content/10.1...

30 days to the launch of Elusive Cures! I learned so much writing it, and I want to share it. For the next 30 days, I'll post brain & mind research breakthroughs on odd days, and highlight unmet needs on even ones. #ElusiveCures30 First breakthrough: /1 press.princeton.edu/books/hardco...

Sharpened visual memory representations are reflected in inferotemporal cortex www.biorxiv.org/content/10.1...

Deep bidirectional interplay between sensory integration and latent rule discovery www.biorxiv.org/content/10.1...

Calling all science advocates!! Carlos Brody+ are creating a searchable database of tangible science benefits, and they need you. publicusaresearchbenefits.com They are asking for suggestions - from brief to lengthy. The database is state-searchable, so all 50 states. Please spread the word!

Happy to share our new paper exploring how the brain might represent decision confidence. A population representation of the confidence in a decision in the parietal cortex: Cell Reports www.cell.com/cell-reports...

Excited to share my latest work just out in @pnas.org! This NIH MOSAIC K99-funded project identifies a top-down cortical circuit—from cingulate to auditory cortex—that supports auditory perceptual performance in challenging listening conditions: www.pnas.org/doi/10.1073/...

A preprint from our lab. Trying something new. "Object categorization based on abstract concepts by monkeys, humans, and vision models" www.biorxiv.org/content/10.1...

We are hiring a PhD student to study the neural mechanisms underlying flexible decision-making and individual variability. Please apply and spread the word!

We are presenting two exciting projects tonight at #Cosyne2025! 🧠🧑‍🔬 [1-032] Changes in tuning curves, not neural population covariance, improve category separability in the primate ventral visual pathway [1-112] Comparing image representations in terms of sensitivities to local distortions

A landmark Computational Neuroscience book for our times, from basic principles to whole-cortex modelling of cognition, NeuroAI and Computational Psychiatry. This is one of Xiao-Jing's major achievements. Years of dedicated work from a master of the field.

This is very interesting, NHP doing a drawing task. Neural representation of action symbols in primate frontal cortex www.biorxiv.org/content/10.1...

Please spread the word!! We are accepting applications for the Cold Spring Harbor Asia Computational and Cognitive Summer School in Suzhou, China. Dates: June 29 to July 20 of 2025. Application deadline: March 31. #computationalneuroscience. For the top three reasons to attend, see thread below:

Latency of vlPFC face selectivity is 30-40ms! Fast face-selective responses in prefrontal face patches of the macaque www.cell.com/cell-reports...

Task structure tailors the geometry of neural representations in human lateral prefrontal cortex www.biorxiv.org/content/10.1...

Robust encoding of stimulus–response mapping by neurons in visual cortex www.pnas.org/doi/10.1073/...

"Beginning February 2025, JNeurosci will permit submission of supplemental materials."😮 www.jneurosci.org/content/info...

I was wondering what's a good review of evidence accumulation/DDM as a primer for students with no background and found this would be very good. www.annualreviews.org/content/jour...

Finally moved here. Hope to enjoy science news and chat in a warm community again.