Our proposal for managing combination therapy while awaiting for susceptibility in Pseudomonas infections. Find out more: journals.plos.org/plosone/arti... #AMSsky #IDsky #PsWatch

Combined antipseudomonal therapy does not improve outcomes and may increase toxicity. Its main role is ensuring appropriate empirical therapy in severe infections, with no proven benefit once susceptibility is known. 📖 A systematic review: www.tandfonline.com/doi/full/10.... #AMSsky #IDsky #PsWatch

En infección urinaria, menos es más 👌🏻 Nuestro hilo sobre diagnóstico y tratamiento de la infección urinaria. ☝🏻 Bacteriuria asintomática #EAAD #WAAW #AMSsky #MedSky #UTIsky (🧵1/2) bsky.app/profile/hosp...

🩺La celulitis infecciosa puede ser difícil de distinguir de otras enfermedades no infecciosas. Estos diagnósticos motivan con frecuencia tratamientos antibióticos innecesarios desde consultas. José Pereyra, dermatólogo, nos da las claves para acertar. #EAAD #WAAW @guiaprioam.bsky.social

🤧💊Los antibióticos no te harán sentir mejor si tienes una infección por virus respiratorios como el COVID o la gripe. Marta Falcón, farmacéutica hospitalaria, nos recuerda los riesgos de la automedicación. #EAAD #WAAW #SomosHUVR @guiaprioam.bsky.social

#WinterIsComing 🥶 Un hilo con nuestras recomendaciones para acertar con tus tratamientos de consulta para las infecciones respiratorias. ☝🏻 Neumonías y EPOC reagudizado #EAAD #WAAW #AMSsky #MedSky #PharmSky (🧵1/4) bsky.app/profile/hosp...

🤧La mayoría de infecciones respiratorias en niños son producidas por virus, y los síntomas no mejorarán por prescribir antibióticos. Ángela Hurtado, pediatra, nos da las claves para un uso prudente de los antibióticos en Pediatría👍🏻#EAAD #WAAW #SomosHUVR

🫁Las infecciones bacterianas respiratorias serán un motivo de consulta frecuente durante el invierno.🩺 Esther Quintana, neumóloga, nos enseña a no fallar en la elección del antibiótico ni en su duración. #EAAD #WAAW #SomosHUVR @guiaprioam.bsky.social

¿Trabajas en consulta? ¡Te necesitamos! El uso prudente de los antibióticos es responsabilidad de todos. Durante toda esta semana, no te pierdas nuestros vídeos para hacer un uso prudente de los antibióticos. 💪🏻 ¡La lucha contra las resistencias empieza en tu consulta! #EAAD #WAAW #AMSsky

¿Trabajas en consulta? ¡Te necesitamos! Durante toda esta semana, no te pierdas nuestra serie de vídeos prácticos para hacer un uso prudente de los antibióticos en tus pacientes ambulatorios 👊🏻 La lucha contra las resistencias, empieza en tu consulta #EAAD #WAAW #AMSsky #MedSky #PharmSky #SomosHUVR

¡Ya tenemos todo listo para el Día Europeo para el Uso Prudente de los Antibióticos! Mantente atento a las redes de @hospitaluvrocio.bsky.social y @guiaprioam.bsky.social durante la semana que viene. Tenemos un mensaje para ti… 😉 #EAAD #WAAW #AMSsky #SomosHUVR

Recruitment for SHORTEN-2 is officially complete! Our team is now wrapping up follow-up and polishing databases. Hope to have results ready in the first half of 2026! Hats off to this awesome research team! 🥳 #AMSsky #IDsky @seimc.bsky.social @ciberisciii.bsky.social @ibis-investigacion.bsky.social

Is antimicrobial stewardship possible in transplant units? In our latest systematic review in @eclinicalmed.bsky.social, we discuss which interventions work, evidence gaps and future research priorities for SOT. 🔓 www.sciencedirect.com/science/arti... #IDSky #AMSsky #TxID Thread below! 🧵(1/6) 👇🏻

It’s encouraging to see new guidelines moving toward shorter and fully-oral treatments for BSIs. We are honoured to see some of our research cited to help shape these recommendations! 😃 #AMSsky #IDsky #UTIsky @hospitaluvrocio.bsky.social @ibis-investigacion.bsky.social bsky.app/profile/jose...

The outpatient Global-PPS is a new, simple tool to measure antimicrobial prescribing in global outpatient settings doi.org/10.1093/jaca... #JACAMRNews #IDSky

As ID physicians, when asked about the importance of ASP, many of us may share the same answers How do we know that today's carbapenem use will lead to a superbug tomorrow? Why worry about resistance decades later, when I have a patient to worry about now. #IDSky academic.oup.com/cid/article/...

Is antimicrobial stewardship possible in transplant units? In our latest systematic review in @eclinicalmed.bsky.social, we discuss which interventions work, evidence gaps and future research priorities for SOT. 🔓 www.sciencedirect.com/science/arti... #IDSky #AMSsky #TxID Thread below! 🧵(1/6) 👇🏻

Today we celebrated our 3rd Annual Researchers’ Meeting at the XXVIII Congress of @seimc.bsky.social! Only 2️⃣4️⃣ patients left to complete the trial! An amazing team doing an amazing work! 🤩🔝 #IDSky #AMSsky #TeamPride

Thanks to @josemolinagb.bsky.social from Seville, Spain, for finding a great Shorter Is Better study from 2021 for bronchiectasis exacerbations! Updated tables attached, with link to website with citations. Had to shrink the font to fit so many RCTs in table! www.bradspellberg.com/shorter-is-b...

Caring for patients with bronchiectasis poses a challenge for both pulmonologists and #AMSky teams. Standard 14d treatments for exacerbations lack good evidence support. This small RCT favors shorter durations such as 8d 👉🏻 publications.ersnet.org/content/erj/... #IDsky @bradspellberg.bsky.social

Pediatric antimicrobial stewardship is catching up fast. Tailored strategies, rising implementation, and tools like "handshake stewardship" are key to optimizing antibiotic use and tackling #AMR in our tiniest patients. #PedsID #Stewardship karger.com/neo/article/... www.idse.net/Review-Artic...

SOT patients have been systematically excluded from most RCTs on treatment duration, leading to prolonged courses still being the standard of care in many centers, even for non-complicated infections. (🧵1/3) #AMSky #IDsky #TxID

Just 23% of patients received AMS support in transplant units. A lot to do for stewies in this field yet! Let’s get to work #AMSky & #TxID! 💪🏼

Not all aspirations need Abx ☺️ aspiration pneumonitis resolves in 24-48h; if symptoms persist >48h, treat aspiration pneumonia with CTX CTX covers key oral anaerobes (eg Peptostreptococcus) so extended anaerobe coverage is usually unnecessary avoid piptaz first-line & reserve for resistant cases

🎙️💊 Sensible y Resistente - Episodio 1 @micromunidad.bsky.social ¿Hasta qué punto importa la duración del tratamiento antibiótico? 🧐 open.spotify.com/episode/4yak31… Hilo con claves y artículos 📚👇#AMSskyk#IDskyky

Systematic review of antibiotic durations in @jac-amr.bsky.social n=315 RCTs 85% demonstrated equivalence or non-inferiority of shorter therapy Only 7% in ICU, 14% in LMIC, and 15% low risk of bias academic.oup.com/jacamr/artic...

Post-discharge prescriptions should be a key focus for #AMSsky! In her fantastic talk at #ESCMIDglobal, @valerievaughnmd.bsky.social showed how >90% of antibiotic duration excess occurs post-discharge! The ROADhome framework can be helpful for this task 👉🏻 academic.oup.com/cid/article/... #IDSky

Already listed in Antibiotic Stewards' Starterpack vol.2! 😉 #AMSsky #IDSky Vol. 1: go.bsky.app/7KcDc2n Vol. 2: go.bsky.app/2qsEveQ

link.springer.com/article/10.1... Short-term vs long term abx treatment for nocardia infections #OncID #idsky

Longer doesn't appear to be better when it comes to antibiotic duration in older adults. #AMSSky academic.oup.com/cid/advance-...

In this table you can find a summary with different antimicrobials’ penetration into the bile (and the peritoneum). Hope you find it useful! 🙂 #AMSsky #IDOnc #IDSky

One antibiotic PK table to rule them all. This is amazing 🙌 #medsky #pharmsky #AMSky #idsky #MedEd

Thx to @absteward.bsky.social for finding a new oral vs. IV osteo RCT! Primary endpoint was re surgery. But, 2nd endpoints = treatment failure, recurrence, and non-union. Similar oral vs. IV outcomes for all outcomes. So this is the 10th RCT now, added to table. bradspellberg.com/oral-antibio...

🆕🔥 systematic review and meta-analysis #CMIJournal 6 RCTs,10 adjusted cohorts& 22 unadjusted cohorts N=11,566 Early transition to oral antibiotics was noninferior to continued IV antibiotic treatment for bacteraemia & sepsis #idsky #medsky www.clinicalmicrobiologyandinfection.com/article/S119...

#idsky #IDSATLRgroup #antimicrobials #stewardship #antibiotic #failure how to think through when someone calls you for advice regarding antibiotic failure #idchalktalk by Drs Miller & Paras idsame.notion.site/ID-Chalk-Tal...

Only 58 patients to go! Recruitment is moving along as planned, and fingers crossed, we’ll be done before summer. Huge shoutout to the @shorten2trial.bsky.social team for keeping up the great work! #AMSsky #IDSky #ShorterIsBetter

For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc. jamanetwork.com/journals/jam...

🆕️🔥Article @thetxidjournal.bsky.social Not Just an Oxymoron: The Utilitarian's Guide to Antimicrobial Stewardship in Transplant Infectious Diseases Table ✨️2: TID ASP opportunities & initiatives #idsky #medsky #Txid onlinelibrary.wiley.com/doi/full/10....

New β-lactams allow treating Pseudomonas that were untreatable, but… are they better than previous options? This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019... 👐🏻 Use them wisely, make them last #PsWatch #AMSsky #IDsky

🌟 ABX Pearl of the Day: Duration of treatment in intra-abdominal infections (IAI)! 💊 💡 Q: How long should I treat IAI after source control? 🔍 A: While STOP-IT trial calls for 4 days post-source control, there are notable exceptions. See infographic for details 👇 #IDsky #AMSsky #MedSky #Pharmsky

It's not only how long, but also how much pressure. A key message to promote earlier de-escalations, especially in high-risk units (ICU, #IDOnc and #TxID). #AMSsky #IDSky

Locum tenens are often necessary at many rural and critical access hospitals. However, they pose significant challenges to healthcare quality and safety. Persuasion and nudge-based interventions are less effective as they practice based on what’s familiar to them rather than what’s appropriate.

What's the best duration for treating uncomplicated P. aeruginosa-BSI? This metaanalysis of observational studies (n=1746) found no differences in recurrence+mortality for short (<10d) compared to prolonged treatments. 📖 www.journalofhospitalinfection.com/article/S019... #PsWatch #AMSsky #IDsky

El capítulo más aterrador de Sensible y Resistente ya está aquí! 💀 Historias de terror y mitos en enfermedades infecciosas con el gran @jdelpoleo y @micromunidad.bsky.social ¿Te atreves a escucharlo? #IDSky #AMSSky Disponible 👇 campus.seimc.org/cursos/detal...

Our @shorten2trial.bsky.social aims to confirm that 7-day treatments are superior to 14-day courses for uncomplicated P. aeruginosa BSI. Check out our full protocol 👉🏻 journals.plos.org/plosone/arti... #AMSsky #IDSky

#ShorterIsBetter in immunocompromised hosts? Short treatments are feasible in early responders without source control issues. A significant number of observational studies serve as proof-of-concept on the feasibility of short courses in selected patients (see ⚠️) #AMSsky #IDOnc #TxID #IDsky

⭐ Excited to share our Clinical Decision Support (CDS) primer article in the Antibiotic Stewardship & Healthcare Epidemiology! 🔬 We featured practical case studies of a 1) Vancomycin advisory alert 2) C Diff order panel at Stanford. doi.org/10.1017/ash.... #MedSky #IDSky #clinicalinformatics #CDS

1/8 💊 Transition from IV to PO #antibiotics We've developed scaleable measures to identify opportunities to transition from IV to PO antibiotics. I will share details 🧵 & wonder whether & how #IDSky might implement these locally. 💊=enteral medication pmc.ncbi.nlm.nih.gov/articles/PMC... #IDSky

Great to see BALANCE trial published! Large RCT of >3,000 patients, >50% in ICU, 7 days non-inferior to 14 days for (mostly) GNR BSI. Solid-organ/stem-cell transplant & neutropenia were excluded. Note: 24% in 7d group received longer duration #IDSky #TxIDSky www.nejm.org/doi/full/10....

Further evidence suggests that adequately dosed oral beta-lactams may achieve results comparable to highly bioavailable antibiotics: www.clinicalmicrobiologyandinfection.com/article/S119.... I think these data are encouraging for expanding our options against uncomplicated BSI! 😀 #AMSsky #IDSky