Ana Deutsch
@anadeutsch.bsky.social
π€ 209
π₯ 169
π 5
PhD student at University of Calgary studying psychedelics
@pact-lab.bsky.social
π§ π
reposted by
Ana Deutsch
Leah Mayo
about 1 month ago
Congrats to
@pact-lab.bsky.social
PhD student
@anadeutsch.bsky.social
on her 1st first-author paper from the lab! π She explored how MDMA & methamphetamine impact cortisol, endocannabinoids, & BDNF levels in healthy humans and how this relates to the subjective drug experience ππ
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The effect of methamphetamine and 3,4-methylenedioxymethamphetamine on peripheral endocannabinoid concentrations: a study in healthy adults - Psychopharmacology
Rationale Stimulant drugs such as methamphetamine (MA) and 3,4-methylenedioxymethamphetamine (MDMA) can impact neurobiological systems implicated in stress, reward processing, and drug use. Although recent preclinical evidence implicates the endocannabinoid (eCB) system in these processes, little is known about the acute effects of stimulants on eCB levels in humans. Objectives The aim of the present study was to investigate the effects of acute administration of the prototypical psychostimulant MA and the psychostimulant-empathogen MDMA on circulating eCB levels in healthy adults. Methods Using a within-subject, double-blind design, this study assessed the acute effects of MA (20 mg), MDMA (100 mg), and placebo on plasma eCB levels in healthy human participants (Nβ=β22) during three separate sessions. Blood samples assessing concentrations of the eCBs anandamide (AEA) and 2-Arachidonoylglycerol (2-AG) were collected between 150- and 180-minutes post-drug administration, and subjective measures of drug effects were collected at regular intervals. Results MA, but not MDMA, was associated with significantly lower 2-AG plasma concentrations compared to placebo. Neither drug impacted AEA concentrations. However, during the placebo condition, higher AEA concentrations were correlated with disliking the βdrug effectsβ, suggesting a possible relationship between AEA levels and negative expectations of subjective drug effects. Conclusions These findings provide novel insights into how stimulant drugs act on the eCB system and may help to develop treatments for SUDs.
https://link.springer.com/article/10.1007/s00213-025-06888-7
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Keira Aubin
about 2 months ago
@anadeutsch.bsky.social
lead her first symposium on stress and psychedelics at
#ebps2025
including her own talk alongside Dr. Gibson Cook and Dr. Helena Aicher. Go Ana π₯³
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Keira Aubin
about 2 months ago
A great EBPS IDEA panel featuring panelists
@anadeutsch.bsky.social
, PhD student Luis Contreras, Dr. Tania Romacho, Dr. Stephanie Garnier, and Dr. Marianne JoΓ«ls
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So happy I got to attend the first
#GRCPsychedelics
conference. Such an amazing opportunity to connect with other researchers & learn about the newest findings in the field.
4 months ago
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Alex Kwan
4 months ago
Science together climb together - sneaked out with fellow
#GRCPsychedelics
attendees for a quick session πͺ
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Ana Deutsch
European Behavioural Pharmacology Society
7 months ago
Parallel Session 6 includes a symposium chaired by
@anadeutsch.bsky.social
exploring how psychedelic trips interact with stress response
#EBPS2025
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So grateful for my lab
add a skeleton here at some point
11 months ago
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Ana Deutsch
Susanne Ahmari
11 months ago
@cerogers.bsky.social
with my favorite comment of the day: "The benefit of aging- really, the only benefitβ is that you care less what other people think of you" πππ π΅
#ACNP2024
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Dr. Connor Haggarty
11 months ago
Interested in
#Cannabinoids
and
#PTSD
? Come see my poster T186, where iβm presenting a study on the effects of
#THC
on emotion regulation in a PTSD population
#ACNP
.
@anadeutsch.bsky.social
is also two spots away, presenting some data on endocannabinoids from an MDMA/MA study I ran in Chicago.
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Ryann Tansey
11 months ago
#ACNP2024
karaoke night!!
@connorhaggarty.bsky.social
@anadeutsch.bsky.social
@hannamolla.bsky.social
@hannahmdouglass.bsky.social
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Ana Deutsch
Dr. Connor Haggarty
11 months ago
A session on my favourite topic
#Cannabis
and a room full of
#Cannabinerds
. Excellent symposium organized by
@mayoonthebrain.bsky.social
and
@jaymemcreynolds.bsky.social
#ACNP2024
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Ana Deutsch
Psychedelic and Cannabinoid Therapeutics (PaCT) Lab
11 months ago
Our postdoc
@ryanntansey.bsky.social
and PhD student
@anadeutsch.bsky.social
take on their first ACNP!
#ACNP2024
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