Gene-edited pig kidneys are finally moving the long-stymied field of xenotransplantation forward. #NIHCMAwardsJournalism scim.ag/4sHbs4C

Bioprothèses valvulaires cardiaques : un mécanisme clé identifié pour expliquer leur compatibilité avec le sang et leur résistance à la calcification Lire le communiqué : presse.inserm.fr/bioprotheses...

New online! Cardiovascular stent technologies for coronary and valvular heart disease: the potential of 3D printing for stent fabrication #CardioSky

After 20 years, 58 generations and more than 30,000 cloning attempts, a team of researchers has hit the limit on the number of times a single mouse can be serially re-cloned go.nature.com/4sDtyET

B Gaye, E Marijon @PARCC showed that African countries are profoundly underrepresented in randomized clinical trials published in the world’s most influential medical and cardiovascular journals. Read more: www.jacc.org/doi/10.1016/...

#seminar on April 9 at noon by Coraline Héron from @parcc-inserm.bsky.social : Impact of Intermittent Hyperglycemia on #Inflammation, Gut #Microbiota, and #Atherosclerosis institutcochin.fr/en/agenda/im... @parispostdocs.bsky.social

D Smadja and colleagues @PARCC showed that endothelial coverage enhances hemocompatibility and prevents calcification in bioprosthetic valve tissue. link.springer.com/article/10.1...

An injectable fluid has been used to close off part of the heart in animals, a potentially improved prevention of stroke in people with irregular heartbeats go.nature.com/4ucNsrs

Retractions, which have long been associated with misconduct or poor scientific practice, can carry a lot of stigma Some in the research community want that to change go.nature.com/46R3tJF

L’attirance contrariée de la recherche française pour la Chine : « On ne joue pas dans la même cour »

P Breillat and B Terrier from PL Tharaux team @PARCC reveal a pathogenic axis in VEXAS syndrome linking UBA1 loss of function and defective ubiquitination to RIPK1-mediated inflammatory cell death, impaired antimicrobial signaling, and defective resolution mechanisms.

The Jouven Team at PARCC has developed an artificial intelligence-based prediction model to identify individuals in the general population at high risk of sudden cardiac death. Read more: academic.oup.com/eurjpc/advan...

JP Empana and X Jouven team @PARCC showed that arteriosclerosis and atherosclerosis compared to healthy vascular aging clusters are independent predictors of CVD, and improve risk stratification for stroke among those at intermediate risk. Read more: www.nature.com/articles/s41...

To support Rare Disease Day today and @medicsforrare.bsky.social, we've launched a Collection of our articles on rare cardiovascular diseases: nature.com/collections/...

Regenerative medicines are headed for people with Parkinson’s disease or severe heart failure — but researchers are concerned about minimal clinical-trial data go.nature.com/4kWN2kJ

Which science jobs are most at risk from AI? To find out, Nature spoke to more than four dozen researchers across academia and industry who use AI in their work. go.nature.com/4cFPvxH

Our March issue is now live, with Reviews on: -Atlases of variant effects to resolve variants of uncertain significance in CVD -AI-enhanced echocardiography -Transcriptional regulation in heart development, disease and regeneration -Arrhythmia-induced cardiomyopathy www.nature.com/nrcardio/vol...

Newly released files from the investigation of convicted sex offender Jeffrey Epstein reveal that his ties to the scientific community were deeper than previously known go.nature.com/4tFtHbT

This platform allows people - or 'meatspace workers' - to advertise their time and skills to AI agents go.nature.com/4aWLVxZ

Massive cuts to global health-care funding have had a huge impact on Africa, but a more resilient system can be built from within go.nature.com/46RnW0G

New online! Vagal mechanoreceptors in the heart sense changes in blood volume #CardioSky

Almost all of the scientists were previously at US institutions go.nature.com/4qMlrUR

Pr Jouven and Dr JP Empana Team @PARCC show that while the incidence of SCA is low, male athletes face a higher risk, especially due to a dangerous final kilometer sprint !! Learn more: academic.oup.com/europace/art...

Don’t overlook the kidney in SARS-CoV-2 pneumonia—even in the absence of overt acute kidney injury @olilen.bsky.social, Pierre-Louis Tharaux & team report on a strong association between kidney-derived proteins and IL-10 levels and mortality: doi.org/10.1172/jci....

ercsg2026.com A stimulating scientific event to present and discuss #kidneydisease #science4health #pathomechanisms #translationalresearch #emergingtherapies and more! The European kidney community will convene in Paris from April 9-12

Une nouvelle étude menée par des scientifiques de l’Inserm montre que le feedback pourrait augmenter la prise de risque sans rendre les décisions plus optimales. Lire le communiqué : presse.inserm.fr/prise-de-ris...

Scientists have developed rearrangeable robotic modules that can “bloom” like flowers to shade a sunlit room by sensing light levels and adapting collectively. Learn more in #ScienceRobotics: https://scim.ag/4jMQais

Thank you Irene Fernandez-Ruiz for this great piece of commentary in @natrevcardiol.nature.com on the IVORY trial published in @natmed.nature.com Main paper can be found here: rdcu.be/eX8W3 @ziadmallat.bsky.social @18fdg.bsky.social @vpd-hlri.bsky.social @medcambridge.bsky.social

"Research is messy. … Trying to protect students from that reality does them a disservice." On #InternationalDayOfEducation, take a look back at this Working Life essay on teaching students about scientific failure. https://scim.ag/4sTaQcH

Dr O. Lenoir, Dr PL. Tharaux @PARCC and colleagues reveal that levels of circulating kidney injury markers and IL-10 identify non-critically ill patients with COVID-19 at risk of death. Learn More: insight.jci.org/articles/vie...

"One email at a time, one informational interview after another, I became comfortable, confident, and strategic in building my network of mentors." One mentor isn’t enough, wrote Erika Moore in this 2021 Working Life essay. https://scim.ag/3Zfm0e8 #NationalMentoringMonth

Are you a grad student struggling with a blank page? These strategies could help go.nature.com/4jGEmhO

Nature research paper: Artificial intelligence tools expand scientists’ impact but contract science’s focus go.nature.com/4pA9hNZ

Dr JP Empana and colleagues @PARCC investigated the prevalence, temporal trends and associated factors of overweight and obesity among adults in the WHO African region. Read more: gh.bmj.com/content/11/1...

Excited to share our latest work published in @pnas.org! 🎉 Our study shows that blood-borne S1P actively maintains vascular resistance, systemic BP and heart function in mice, with distinct contributions from different circulating S1P pools www.pnas.org/doi/10.1073/... @parcc-inserm.bsky.social

Dans un essai clinique de phase 2, une équipe de l'Inserm montre l’efficacité d’un nouveau traitement pour réduire l'inflammation chronique ou résiduelle qui peut être observée après un syndrome coronaire aigu (SCA). Lire le communiqué : presse.inserm.fr/syndrome-cor...

📢Candidatez à la prochaine édition du Challenge Starthèse qui accompagne les doctorants & jeunes chercheurs dans la valorisation de leurs expérience de thèse, compétences doctorales et travaux de recherche 📆Fermeture des candidatures : 09/02 👉 swll.to/iZT4L

Dr E Camerer and colleagues @PARCC uncover an essential role for circulating S1P in maintaining blood pressure and left ventricular systolic function. They also highlight distinct functions for the pools of S1P bound to HDL or to albumin. www.pnas.org/doi/10.1073/...

Pr Z Mallat @PARCC and colleagues show that, in patients with acute coronary syndromes, low-dose IL-2 safely increases Treg cell levels and reduces arterial inflammation. Learn More: www.nature.com/articles/s41...

A 3D printed guide that reconnects right vagus nerve and heart preserved cardiac function and helped regrow resected nerve in minipigs, with therapeutic potential for thoracic surgery and transplantation. Learn more in #ScienceTranslationalMedicine: https://scim.ag/49eworw

B. Gaye and E. Marijon @PARCC, in collaboration with colleagues from the ERADICATE Consortium (Ending Rheumatic Heart Disease through Advanced Diagnosis, Intervention, Care, Access, Treatment, and Equity), are leading a strategy aimed at eradicating rheumatic heart disease. doi.org/10.1093/eurh...

A Eichmann and Colleagues @PARCC showed that endothelial ROCK1 and 2 maintain junctional integrity and ensure proper angiogenesis and lumen formation. These data also indicate the need for careful consideration when using ROCK inhibitors in disease settings. doi.org/10.1093/cvr/...

Pr D Smadja @PARCC calls to action for Health desinformation. the next battle for public health will be waged not only in hospitals and laboratories but also in the information spaces where truth competes with virality. It is time for science to go viral—for the right reason!

Dans une nouvelle étude des scientifiques de l'Inserm ont analysé comment le système lymphatique se dérègle dans l’insuffisance cardiaque. Ils ont, pour la première fois, identifié les mécanismes responsables de ce dysfonctionnement. Lire le communiqué : presse.inserm.fr/decouverte-d...

Pr D Smadja @PARCC and colleagues confirmed the absence of vascular benefit of Hydroxychloroquine (HCQ) treatment, reinforcing evidence against HCQ’s clinical utility in COVID-19 and underscoring the need for alternative endothelial-targeted approaches. link.springer.com/article/10.1...

L’ANR participe au nouvel appel à projets transnational du partenariat européen pour la médecine personnalisée, EP PerMed : "Médecine Personnalisée pour les maladies #cardiovasculaires, #métaboliques et #rénales" #CARMEN2026 📆 10/02/2026 (pré-propositions) ➡ anr.fr/CARMEN2026

Susan Monarez was fired after less than a month as Director of the CDC for holding the line on scientific integrity She is part of Nature's 10 - our list of people who shaped science in 2025 go.nature.com/48FnHpx