Print version out now in @science.org Microtubule dynamics control the direction of cardiomyocyte growth | Science www.science.org/doi/10.1126/...

A sweeping analysis of sleep duration and signs of ageing in half a million adults has pinpointed a sweet spot that is linked to a lower risk of early death and disease go.nature.com/4uLh8eE

A sweeping analysis of sleep duration and signs of ageing in half a million adults has pinpointed a sweet spot that is linked to a lower risk of early death and disease go.nature.com/49wfQMl

Team Ait-Oufella and Empana showed that in people without personal history of cardiovascular disease (CVD), higher concentration of triggering receptor expressed on myeloid cells 1 was associated with a higher risk for CVD occurrence. Read more: academic.oup.com/eurjpc/advan...

Book review 📚 The sleep paradox: why do humans sleep so little when we need it so much? go.nature.com/4uN92lY

Experienced researchers are less likely to produce ‘disruptive’ science than are those just starting their careers, finds an analysis of the scientific papers published by 12.5 million researchers over 60 years. go.nature.com/4uUvMk3

An audit of 2.5 million academic papers has identified nearly 3,000 biomedical-science papers that contain fake references. go.nature.com/42iMcX4

Diabetic kidney disease is the leading cause of kidney failure worldwide go.nature.com/4cZDoKx

Menasché team @PARCC evaluate whether using CAR-T cells to target the protein FAP can eliminate cardiac fibrosis in Duchenne Muscular Dystrophy, potentially overcoming a major barrier to the efficacy of traditional gene-correction therapies. Read more: link.springer.com/article/10.1...

Red blood cells modified with Nobel-prizewinning chemistry can snap together to form clots that staunch bleeding in seconds go.nature.com/4ddMOTZ

🚨 How do mechanical forces shape a developing organ? Our new #ScienceAdvances @science.org study, led by the amazing @cvagenapantoula.bsky.social, reveals a Piezo1-driven hydraulic mechanism, where mechanical cues control cell volume to guide cardiac formation ❤️🐟 🔗 www.science.org/doi/10.1126/...

Team Loupy @PARCC tested how 10 different data normalization methods affect the performance of the Banff Human Organ Transplant (B-HOT) gene panel for diagnosing kidney transplant rejection. Read more: journals.lww.com/jasn/abstrac...

Almost all organs and tissues in the body can develop tumours, but those that affect the heart are seldom observed go.nature.com/4e7vn8K

Redefining Healthcare in the Age of AI, a Nature Conference, will explore the transformative impact of AI on modern medicine To register: www.nature.com/naturecareer...

Pour la première fois, l'Inserm a réalisé une expertise collective sur le dopage, à partir des données scientifiques les plus récentes pour analyser et mesurer l'ampleur du phénomène. Lire le dossier de presse : presse.inserm.fr/expertise-co...

Failure is part and parcel of research, but discussing it sometimes seems to be taboo in science. It doesn’t need to be go.nature.com/3QHXZvk

The Loupy Team @PARCC has developed and externally validated a high-precision prediction model for mortality in kidney transplant recipients. The model provides accurate risk stratification that enables clinicians to make more informed, personalized medical decisions. jamanetwork.com/journals/jam...

Ageing remodels the immune system differently in men and women — with a shift in women towards immune cells that are linked to autoimmune conditions go.nature.com/4mCfcCu

"France's leadership could trigger the beginning of a renaissance in political commitment, partnership, and science-based decision making for health." Richard Horton reflects on the International Summit on One Health held in Lyon earlier this month: tinyurl.com/2nht6xvy

The Spontaneous Coronary Artery Dissection risk at ZNF827 (rs13128814) is driven by NF1 binding in vascular cells. ZNF827 regulates gene expression in smooth muscle cells and fibroblasts, linking it to arterial fragility and cardiovascular traits. Read more: portlandpress.com/clinsci/arti...

New online! Extremes of temperature and cardiovascular mortality #CardioSky

🌐 One Health is on the agenda. Join The Lancet’s Richard Horton live at the One Health Summit High-level Session. Tomorrow, global leaders meet in Lyon & online to accelerate action—and The Lancet is part of it. Learn more: spkl.io/63321A2ZrU

H Ait-Oufella and Colleagues @PARCC reveal a detrimental role for NK cells following acute myocardial infarction and highlight NK cells as potential therapeutic targets to limit adverse cardiac remodeling. Read more: www.nature.com/articles/s41...

Gene-edited pig kidneys are finally moving the long-stymied field of xenotransplantation forward. #NIHCMAwardsJournalism scim.ag/4sHbs4C

Bioprothèses valvulaires cardiaques : un mécanisme clé identifié pour expliquer leur compatibilité avec le sang et leur résistance à la calcification Lire le communiqué : presse.inserm.fr/bioprotheses...

New online! Cardiovascular stent technologies for coronary and valvular heart disease: the potential of 3D printing for stent fabrication #CardioSky

After 20 years, 58 generations and more than 30,000 cloning attempts, a team of researchers has hit the limit on the number of times a single mouse can be serially re-cloned go.nature.com/4sDtyET

B Gaye, E Marijon @PARCC showed that African countries are profoundly underrepresented in randomized clinical trials published in the world’s most influential medical and cardiovascular journals. Read more: www.jacc.org/doi/10.1016/...

#seminar on April 9 at noon by Coraline Héron from @parcc-inserm.bsky.social : Impact of Intermittent Hyperglycemia on #Inflammation, Gut #Microbiota, and #Atherosclerosis institutcochin.fr/en/agenda/im... @parispostdocs.bsky.social

D Smadja and colleagues @PARCC showed that endothelial coverage enhances hemocompatibility and prevents calcification in bioprosthetic valve tissue. link.springer.com/article/10.1...

An injectable fluid has been used to close off part of the heart in animals, a potentially improved prevention of stroke in people with irregular heartbeats go.nature.com/4ucNsrs

Retractions, which have long been associated with misconduct or poor scientific practice, can carry a lot of stigma Some in the research community want that to change go.nature.com/46R3tJF

L’attirance contrariée de la recherche française pour la Chine : « On ne joue pas dans la même cour »

P Breillat and B Terrier from PL Tharaux team @PARCC reveal a pathogenic axis in VEXAS syndrome linking UBA1 loss of function and defective ubiquitination to RIPK1-mediated inflammatory cell death, impaired antimicrobial signaling, and defective resolution mechanisms.

The Jouven Team at PARCC has developed an artificial intelligence-based prediction model to identify individuals in the general population at high risk of sudden cardiac death. Read more: academic.oup.com/eurjpc/advan...

JP Empana and X Jouven team @PARCC showed that arteriosclerosis and atherosclerosis compared to healthy vascular aging clusters are independent predictors of CVD, and improve risk stratification for stroke among those at intermediate risk. Read more: www.nature.com/articles/s41...

To support Rare Disease Day today and @medicsforrare.bsky.social, we've launched a Collection of our articles on rare cardiovascular diseases: nature.com/collections/...

Regenerative medicines are headed for people with Parkinson’s disease or severe heart failure — but researchers are concerned about minimal clinical-trial data go.nature.com/4kWN2kJ

Which science jobs are most at risk from AI? To find out, Nature spoke to more than four dozen researchers across academia and industry who use AI in their work. go.nature.com/4cFPvxH

Our March issue is now live, with Reviews on: -Atlases of variant effects to resolve variants of uncertain significance in CVD -AI-enhanced echocardiography -Transcriptional regulation in heart development, disease and regeneration -Arrhythmia-induced cardiomyopathy www.nature.com/nrcardio/vol...

Newly released files from the investigation of convicted sex offender Jeffrey Epstein reveal that his ties to the scientific community were deeper than previously known go.nature.com/4tFtHbT

This platform allows people - or 'meatspace workers' - to advertise their time and skills to AI agents go.nature.com/4aWLVxZ

Massive cuts to global health-care funding have had a huge impact on Africa, but a more resilient system can be built from within go.nature.com/46RnW0G

New online! Vagal mechanoreceptors in the heart sense changes in blood volume #CardioSky

Almost all of the scientists were previously at US institutions go.nature.com/4qMlrUR

Pr Jouven and Dr JP Empana Team @PARCC show that while the incidence of SCA is low, male athletes face a higher risk, especially due to a dangerous final kilometer sprint !! Learn more: academic.oup.com/europace/art...

Don’t overlook the kidney in SARS-CoV-2 pneumonia—even in the absence of overt acute kidney injury @olilen.bsky.social, Pierre-Louis Tharaux & team report on a strong association between kidney-derived proteins and IL-10 levels and mortality: doi.org/10.1172/jci....

ercsg2026.com A stimulating scientific event to present and discuss #kidneydisease #science4health #pathomechanisms #translationalresearch #emergingtherapies and more! The European kidney community will convene in Paris from April 9-12

Une nouvelle étude menée par des scientifiques de l’Inserm montre que le feedback pourrait augmenter la prise de risque sans rendre les décisions plus optimales. Lire le communiqué : presse.inserm.fr/prise-de-ris...