Beatrice Borsari
@beaborsari.bsky.social
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Assistant Professor of Genetics @ Universitat de Barcelona Serra-Hunter Fellow
reposted by
Beatrice Borsari
4 months ago
New
@natcomms.nature.com
paper led by
@beaborsari.bsky.social
& Mor Frank. Also thanks to co-authors Eve Wattenberg,
@xuke0828.bsky.social
, Susanna Liu, Xuezhu Yu &
@markgerstein.bsky.social
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reposted by
Beatrice Borsari
4 months ago
Curious how your favorite gene changes when and how during a biological process? Want to dive into the kinetics of chromatin + gene expression? Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...
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The chronODE framework for modelling multi-omic time series with ordinary differential equations and machine learning - Nature Communications
Here, the authors use a simple equation to study how genes and their regulators switch on/off over time, across the whole genome in tissues and cells. Most changes are gradual, but some genes switch q...
https://doi.org/10.1038/s41467-025-61921-9
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