Sarah Alexander
@sarah1alexander.bsky.social
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📥 286
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Mum, Scientist, STI microbiologist, European and Slow runner. All views are my own!
reposted by
Sarah Alexander
British Association for Sexual Health and HIV (BASHH)
about 13 hours ago
Lizzie Dale, the STASHH BSIG Representative, has given an insightful run-down of BSIG's new competencies assessment tool for microscopy in a newly published blog. 🔬 Read Lizzie's full blog via our LinkedIn page:
bit.ly/47wsf2t
to find out more about the new tool and how to access it.
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reposted by
Sarah Alexander
Gwen Pearson
3 days ago
And now for something completely different:
#EntSoc25
Entomologists! Please contribute to the iNaturalist collection of pubic lice! It's mostly from the EU at the moment.
www.inaturalist.org/taxa/395978-...
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Crab Louse (Pthirus pubis)
The crab louse or pubic louse (Pthirus pubis) is an insect that is an obligate ectoparasite of humans, feeding exclusively on blood. The crab louse usually is found in the person's pubic hair. Althoug...
https://www.inaturalist.org/taxa/395978-Pthirus-pubis#map-tab
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Surely every case of congenital syphilis could be prevented with tests and treatment but important message never the less....
add a skeleton here at some point
11 days ago
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reposted by
Sarah Alexander
Zamin Iqbal
22 days ago
Podcast with me and
@turiking.bsky.social
for the
@milnerevolution.bsky.social
series, on plasmid evolution over the last 100 years, talking about our (
@cazares-adr.bsky.social
, Nick Thomson,
@sarah1alexander.bsky.social
& co) recent paper
www.science.org/doi/10.1126/...
youtu.be/Mzr3TD4ijs0?...
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How the Vectors of Antibiotic Resistance Have Evolved - Professor Zamin Iqbal
YouTube video by Milner Centre for Evolution
https://youtu.be/Mzr3TD4ijs0?si=jq6x4oG4ZTNEP3YO
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100% of Penile cancer is preventable!
28 days ago
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Next up - interesctionality and inequalities. IUSTI2025
28 days ago
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Very informative presentation by Kate Nambiar - common presentations in trans men accessing sexual health services
#IUSTI
28 days ago
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Fabulous presentation by Dr. Janet Wilson at IUSTI2025. We should treat BV as a neglected condition
28 days ago
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Why does BV not resolve? Because of biofilms!
#IUSTI
28 days ago
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Partner treatment for BV works and is well tolerated
#IUSTI25
28 days ago
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With regards to BV there is correlation between male and female microbiomes.
#IUSTI25
28 days ago
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Serious adverse events associated with BV. However treatment has not changed or improved for 30 years.
#IUSTI25
28 days ago
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reposted by
Sarah Alexander
Alt CDC (they/them)
28 days ago
Good night, friends. Tonight was deeply painful. We at CDC do this work because we care. It’s long hours, often feeling overworked and not enough pay, but we do it because we want to make the world a better place.
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reposted by
Sarah Alexander
Sheryl Gay Stolberg
28 days ago
BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:
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reposted by
Sarah Alexander
Dr John Gilmore
29 days ago
Great to be in Athens for the 38th Annual IUSTI Europe Congress (International Union Against Sexually Transmitted Infection). I’m presenting our work on Awareness, Attitudes and early Use of DoxyPEP in Ireland!
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Regulatory barriers prevent good quality tests getting to market! The system needs to be reformed
#IUSTI2025
29 days ago
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We need to reduce the incidence of GC why we have drugs that work: in MGEN we need to reduce testing, and preserve the drugs that we have. IUSTI25 - amazing presentation by David Lewis
29 days ago
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Cephalosporin resistance in Ng globally is a worry and there are lots of areas which we do not know what is going on
#IUSTI25
29 days ago
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We need regulatory reform for tests! IUSTI25
29 days ago
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Tests are getting smaller, better, faster
29 days ago
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Our lab tests are too sensitive and detect exposure and not infection
#IUSTI25
29 days ago
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Not every bug causes an infection! We don’t need hyper sensitive tests
29 days ago
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What do we need for diagnostics? Tools to detect for resistance! The STI bugs travel together
#IUSTI25
29 days ago
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Fabulous session organised by
#BASHH
meeting the
#IUSTI25
scholars
29 days ago
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Fabulous to be at the WHO workshop STI control in difficult times
#IUSTI25
29 days ago
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reposted by
Sarah Alexander
Onisillos
about 1 month ago
I made another attempt at providing some insight into the journals process (To prevent procrastination, I didn’t proofread it. So don’t judge it too harshly)
open.substack.com/pub/onisillo...
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Rejection doesn't mean your paper was bad
It's disappointing, but try to not take it personally.
https://open.substack.com/pub/onisillos/p/rejection-doesnt-mean-your-paper?r=d2ge1&utm_medium=ios
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reposted by
Sarah Alexander
Wellcome Sanger Institute
about 1 month ago
Samples from 1917 have helped identify the genetic culprits responsible for the spread of treatment-resistant infections 🔎 By mapping plasmid evolution since the pre-antibiotic era, experts found that a minority of plasmids cause most of the multidrug resistance in the world 🧵
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reposted by
Sarah Alexander
Roland Pease
about 1 month ago
Talking to
@zaminiqbal.bsky.social
about plasmids and bacterial adaptability was a delight. A brilliant metaphor every other sentence, almost.
add a skeleton here at some point
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reposted by
Sarah Alexander
Zamin Iqbal
about 1 month ago
If you can't face reading War and Peace or my massive thread, I was interviewed on BBC Science in Action, you can hear me 12 mins into this episode (we are not the headline paper, which was on autism):
www.bbc.co.uk/sounds/play/...
add a skeleton here at some point
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reposted by
Sarah Alexander
British Association for Sexual Health and HIV (BASHH)
about 1 month ago
Happy
#WorldContraceptionDay
! BASHH believes in the importance of non-judgemental access to a wide range of contraception options, and improving access to effective education and services. Access Brook's advice on contraception:
bit.ly/47dc20p
#WCD2025
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The quote of the day about griffins! Brilliant tread- about plasmid evolution- Game oF Thrones at a molecular biology level
add a skeleton here at some point
about 1 month ago
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reposted by
Sarah Alexander
Alex Merz 🇺🇸🇨🇦🇺🇦
about 1 month ago
Much improved over the preprint, and the preprint was awesome.
add a skeleton here at some point
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please read this thread - even if you don;t get time to read the paper!!!!! just the best - great work, really really great.
add a skeleton here at some point
about 1 month ago
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reposted by
Sarah Alexander
Kate Baker
about 2 months ago
(Alluding to what happened for chlamydia in Sweden 🇸🇪 for those new to the area
sti.bmj.com/content/96/5...
)
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Rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study
Objectives A new variant of Chlamydia trachomatis (nvCT) was discovered in Sweden in 2006. The nvCT has a plasmid deletion, which escaped detection by two nucleic acid amplification tests (Abbott-Roch...
https://sti.bmj.com/content/96/5/375
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reposted by
Sarah Alexander
Kate Baker
about 2 months ago
History repeats itself: more disappearing STIs from molecular target mutation 😬 Great 🕵️ work by
@sarah1alexander.bsky.social
and colleagues!
add a skeleton here at some point
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reposted by
Sarah Alexander
Lewis C. E. Mason
2 months ago
How should
#XDR
#shigellosis
cases be treated? Our new education piece at
#BMJ
#SexuallyTransmittedInfections
explores specific empirical treatment. Our recommendations are subsequent to our microbial genomic, phenotypic
#AMR
, and clinical/pharmacological analyses.
sti.bmj.com/content/earl...
🧫💻🛟🧪🧬🦠
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Antimicrobial treatment options for extensively drug-resistant (XDR) shigellosis in men who have sex with men
The sexual transmission of Shigella s onnei and Shigella flexneri has been observed since the 1970s between men who have sex with men (MSM) associated with living with HIV, sexually transmitted infect...
https://sti.bmj.com/content/early/2025/08/27/sextrans-2025-056612
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reposted by
Sarah Alexander
Eurosurveillance journal
about 2 months ago
This week's rapid communications describe ➡️A strain of Neisseria gonorrhoeae producing false negative results on Xpert CT/NG assay in England 🔎An atypical sixfold rise in
#influenza
A(H1N1)pdm09 cases in Denmark during summer Full issue here 👉
bit.ly/eus2036
#EpiSky
#IDSky
#MedSky
#STISky
🛟🦠🧫⚕️
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The
@ukhsa.bsky.social
STI Reference Lab has identified a strain of Neisseria gonorrhoeae which evades detection on the Cepheid Xpert CT/GC Assay. Read more in our eurosurveillance article
www.eurosurveillance.org/content/10.2...
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Detection and characterisation of Xpert CT/NG assay Neisseria gonorrhoeae diagnostic escape mutants, England, June 2025
We report the timely detection of a strain of Neisseria gonorrhoeae which was confirmed as a diagnostic escape mutant on the Cepheid Xpert CT/NG assay in England in June 2025. The reason for assay failure was a likely recombination event with Neisseria meningitidis, which removed both assay target sites. Seven historical putative Xpert CT/NG assay diagnostic escape mutants were also identified following subsequent in silico screening of gonococcal genome collections, but currently there is no evidence of widespread circulation.
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.36.2500673
about 2 months ago
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reposted by
Sarah Alexander
Alt CDC (they/them)
2 months ago
Our veterans put their bodies on the line for our freedoms. And in return, we demand even more control over their bodies? Abortion is a medical decision to be made by the patient and their medical providers. Limiting abortion access increases maternal mortality. We are seeing that in Texas already
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reposted by
Sarah Alexander
WHO
3 months ago
Access to safe abortion protects the health of women and girls. As with all other health services, women and girls should be able to access safe and respectful abortion care, when they need it, without fear of harm, punishment or recrimination.
#HealthForAll
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reposted by
Sarah Alexander
Nicola Low
3 months ago
#stihiv2025
🧪 Closing plenary
@drjeannem.bsky.social
on
#DoxyPEP
Clearly reduces
#syphilis
#chlamydia
But
#gonorrhoea
… Staph. aureus resistance and group A Strep increases Potential to drive ceftriaxone resistance in N. gonorrhoeae - which will be a *real problem
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reposted by
Sarah Alexander
Nicola Low
3 months ago
#stihiv2025
🧪 Closing plenary
@drjeannem.bsky.social
Great promise of long-acting HIV PrEP, if available, accessible, in a functioning health system All it takes is a disaster… Like withdrawal of PEPFAR - a humanitarian crisis 👇
@avac.org
counter of preventable deaths
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reposted by
Sarah Alexander
AVAC
3 months ago
“Silence equals death. We cannot go back there. We must resist erasure and rebuild trust with communities we’ve abandoned.” — Jeanne Marrazzo at the
#STIHIV2025
closing, calling for renewed
#STI
&
#HIV
activism, diversified funding & unapologetic advocacy.
@stihiv2025.org
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Always an inspiration Dr. Marrazzo - provides loads of hope, keep passionately advocating! We need honest conversations, work with our community partners and don’t lose ground - fantastic
#STIHIV2025
3 months ago
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reposted by
Sarah Alexander
Trish Greenhalgh
3 months ago
In Oxford? Got kids? There’s a great exhibition of stunning blown-up photos of insects (plus lots more) at the Museum of Natural History
www.oumnh.ox.ac.uk/event/micros...
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Microsculpture
Over the coming months, as we work on their new, permanent displays, our 6 latest display cases will feature an exhibition of work by British photographer Levon Biss.
https://www.oumnh.ox.ac.uk/event/microsculpture
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Adolescent girls x6 more likely than boys in eastern and Southern Africa to acquire HIV
3 months ago
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What about the women???? No good news for women.... again "Dr Marrazzo"
3 months ago
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chlamydia manipulates neutrophils and host cells! master manipulator
#STIHIV2025
3 months ago
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Vaccines for STIs - good start
3 months ago
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reposted by
Sarah Alexander
Nicola Low
3 months ago
#stihiv2025
🧪 day 3 Helen Rees on STI vaccines 💉 Vaccine hesitancy a growing problem to address if we want STI vaccines 💉 to be successful Confidence Complacency Convenience Context
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