@slimfourati.bsky.social
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Fantastic Flavivirus meeting ! Great science and great networking
8 days ago
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Happy to share our preprint “ICU patients with influenza during 2025–26 : a French nationwide cohort study”, conducted within the SEVARVIR consortium, supported and funded by ANRS-MIE. Severe H3N2 in 25–26 (subclade K) did not worsen outcomes in ICU patients.
www.medrxiv.org/content/10.6...
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Clinical and virological characteristics of critically ill patients with influenza in France during the 2025/26 season, marked by the emergence of influenza A(H3N2) clade K
Importance: Recent reports have highlighted an intense influenza activity related to the circulation of the influenza A(H3N2) subclade k variant. There is no data available on the impact of the emerge...
https://www.medrxiv.org/content/10.64898/2026.02.20.26346693v1
about 2 months ago
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reposted by
Eric Topol
6 months ago
How do mRNA vaccines help fight cancer? A
@nature.com
paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
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How mRNA Vaccines Can Help Fight Cancer
Turning "cold" tumors "hot"
https://erictopol.substack.com/p/how-mrna-vaccines-can-help-fight
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reposted by
Eric Topol
10 months ago
Not just shingles vaccine, but also RSV vaccine reduces the risk of dementia, which highlights the benefit of revving up the immune system in older individuals
www.nature.com/articles/s41...
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Lower risk of dementia with AS01-adjuvanted vaccination against shingles and respiratory syncytial virus infections - npj Vaccines
npj Vaccines - Lower risk of dementia with AS01-adjuvanted vaccination against shingles and respiratory syncytial virus infections
https://www.nature.com/articles/s41541-025-01172-3
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reposted by
Edward Nirenberg
10 months ago
In some good news- this is an interesting idea. Lencapavirification (yes I made that term up) of flu antivirals:
www.science.org/content/arti...
Details on the drug here.
www.nature.com/articles/s41...
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A single shot of a flu drug could outperform vaccines—and protect for an entire season
One injection of a long-lasting drug showed up to 76% efficacy in a large trial
https://www.science.org/content/article/single-shot-flu-drug-could-outperform-vaccines-and-protect-entire-season
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reposted by
The Journal of Infectious Diseases
about 1 year ago
Molecular characterization of RSV infections in elderly patients during the 2023/2024 season in the era of nirsevimab introduction âś… Just Accepted
#IDSky
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Molecular characterization of RSV infections in elderly patients during the 2023/2024 season in the era of nirsevimab introduction
RSV can cause severe infections in the elderly. Nirsevimab is a novel prophylactic monoclonal antibody, widely used in infants in France during the 2023/2024 season. It may select for resistant RSV variants that, if transmitted in the community, could compromise vaccine efficacy in the elderly.
https://buff.ly/4gv0N6r
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