Excited to share our preprint on spatial transcriptomics of human sympathetic chain ganglia and the effect of diabetes. We also compared sympathetic and dorsal root ganglia to identify ganglia-specific signatures. Work led by @marisolmancilla.bsky.social doi.org/10.1101/2025...

Our collaborative paper with Isaac Chiu's lab was published today: www.sciencedirect.com/science/arti... It is a really cool finding on how Staphylococcus V8 protease drives the itch-scratch cycle via PAR1 activation. We did the human DRG work. Huge congrats to Liwen Deng, who led this work.

We received positive reviews on our work on TMEM97 modulators for neuropathic pain and have now posted a revision to our paper on @biorxiv-neursci.bsky.social @biorxiv-bioinfo.bsky.social www.biorxiv.org/content/10.1... led by Saad Yousuf in my lab and Jim Sahn in Stephen Martin's lab at UT Austin