Jenn Orthmann Murphy
@jennoligomyelin.bsky.social
📤 259
đź“Ą 412
đź“ť 8
Fantastic session this morning at
#ANA2025
on 'Communicating your Science' with Drs. S. Andrew Josephson,
@rkchoi.bsky.social
, Sara Manning and Kelly Sloane
19 days ago
0
3
1
reposted by
Jenn Orthmann Murphy
Journal of General Physiology
4 months ago
Gong,
@jennoligomyelin.bsky.social
, Abrams et al. present two novel, disease-causing genetic variants of
#connexin
47. In vitro assays and MD simulations reveal unique mechanisms that relate connexin 47 mutations to severities of Pelizaeus–Merzbacher-like disease 1.
rupress.org/jgp/article/...
0
1
1
We had a beautiful day for the Philly WalkMS for
@nationalmssociety.bsky.social
. Team
#Gliadelphia
@pennmedicine.bsky.social
MS Division and
@pennngg.bsky.social
was there to support our friends, family and patients
5 months ago
0
10
2
Excited to Share FAST - a free and user-friendly way to segment and track cells in longitudinal in vivo imaging sets. We developed it for
#oligodendrocytes
but it also works for
#astrocytes
!
#Gliadelphia
@pennmedicine.bsky.social
www.eneuro.org/content/12/2...
loading . . .
FAST: Fast, Free, Consistent, and Unsupervised Oligodendrocyte Segmentation and Tracking System
To develop reparative therapies for neurological disorders like multiple sclerosis (MS), we need to better understand the physiology of loss and replacement of oligodendrocytes, the cells that make my...
https://www.eneuro.org/content/12/2/ENEURO.0025-24.2024
6 months ago
2
3
0
reposted by
Jenn Orthmann Murphy
Shane Liddelow
7 months ago
#GRCGlia25
#DwightBirdles
is hanging out with his family!
0
20
4
reposted by
Jenn Orthmann Murphy
Xilma Ortiz-Gonzalez MD PhD
7 months ago
Standing up for science by sharing this labor of ❤️ out today! What underlies selective neuronal vulnerability in rare 🧬 disorders when the gene is ubiquitously expressed? TBCK patient derived neurons have axonal predominant lysosomal and mRNA trafficking defects, 👇🏽
www.biorxiv.org/content/10.1...
loading . . .
TBCK-deficiency leads to compartment-specific mRNA and lysosomal trafficking defects in patient-derived neurons
Monogenic pediatric neurodegenerative disorders can reveal fundamental cellular mechanisms that underlie selective neuronal vulnerability. TBCK-Encephaloneuronopathy (TBCKE) is a rare autosomal recess...
https://www.biorxiv.org/content/10.1101/2025.03.02.641041v1
1
10
3
Today I was honored to represent the CSF1R-ALSP workgroup at the GLIA-CTN Scientific Conference here in
#Gliadelphia
and support Sisters' Hope Foundation and the CSF1R-ALSP community. Shown are workgroup members who were able to attend in person.
7 months ago
0
8
0
Congratulations to Hannah Loo, the first lab graduate, on her thesis defense and submission of her paper
10 months ago
1
16
0
you reached the end!!
feeds!
log in
