Join us for an educational webinar with Peripheral Nerve Society on April 29 (register below) “Metabolic Disease and Peripheral Neuropathy – Mechanistic Insights from Bench to Bedside” with me, Chris Gibbons (Harvard), and Brian Callaghan (UMichigan). 🧪https://tinyurl.com/mvjs5xjc

In a new Science study, researchers introduce DrugCLIP, a contrastive learning framework that virtually screens small molecules and protein pockets, analyzing protein-ligand interactions 10 million times faster than most standard molecular docking approaches. https://scim.ag/45FfSj2

Most beautiful science of 2025, from @nautil.us 🧪🧪 nautil.us/the-most-bea...

#Science2025-6 🧪🧪 Former Pepsico CEO Indra Nooyi: “Sometimes people say, “Oh, you flip-flop.” No, the environment changed. ... You cannot be dogmatic about your strategic direction. When the environment changes around you, you’ve got to zag a little bit." From @farnamstreet.bsky.social

Such a well-deserved recognition, and a discovery that continues to have huge impacts on research in the brain. Congrats!!

New forecasted R25 opportunities in research training. Research Experiences: simpler.grants.gov/opportunity/...

Non-competitive renewal awards. On a more or less normal curve but not catching up from the government shutdown-related delay. All ICs except for NIAAA and NCCIH have made some awards with NIAID having made the most at 579. 2/2

Quoted in New Scientist today, coverage by Linda Geddes, 2 articles reveal nuanced functions of adipose conferring health benefits around the body. Links below @newscientist.com 🧪🧪https://www.newscientist.com/article/2511715-body-fat-supports-your-health-in-surprisingly-complex-ways/

Only well-off AAAS fellows are "ok"; the rest of us aren't. If the science minibus passes, the decimation remains. Colette notes NIH ECRs are crushed. NCAR is not explicitly protected. Money won't arrive before a 5% grant success rate at NASA planetary forces more ECRs out after the 20% NASA RIF.

*not including NIH

2025 was the hottest year on record for ocean heat content. Unfortunately, we now say this every year. 🥹 "In addition to setting a new record in 2025, the global ocean continues to show sustained and intensified warming." + #OpenAccess Study: doi.org/10.1007/s003... + Data: www.ocean.iap.ac.cn

For anyone interested in the new Dietary Guidelines, here's a breakdown and my thoughts: kcklatt.substack.com/p/ambiguous-...

Doing tactile things has been helping my anxiety, and my genius sister-in-law made an app that prompts a daily doodle and I'm LOVING it. She just put out the beta. Main rule: NO AI. I'm 2/skwurlhat on there. Come draw with us. It's so nice. www.doodl.app/join-the-beta

Every. Single. Day.

What’s Entering the Public Domain in 2026: Faulkner’s As I Lay Dying, All Quiet on the Western Front, Betty Boop & More

This. And “I can speak loudly, I don’t need a mic” is also not considerate.

A reminder that applications for the MIT KSJ Fellowship close this Friday, January 9. So if you're applying this year, get those applications and references in. ksj.mit.edu/fellowships/...

And this is why I have literally SCHEDULED time to be able to do this in Jan.

Studies of goal setting reveal why it’s so hard to keep resolutions—and how to make ones that actually stick

We are hiring a new clinical research assistant for our NIH-funded clinical trial - learn more and link to apply here tinyurl.com/vbank9uz 🧪🧪

Another great line-up for the 2nd annual Adipose Biology Conference in Montreal in 2026! Organized by Kazak, Sung and Beaudry. Truly enjoyed the ABC in 2025, highly recommend! 🧪🧪

Ultimately, our graphics should tell a story about our research, whether it’s about changing media habits or shifting social norms. Here's a few of our favorite visuals from 2025, how we made them, and what makes them successful.

This really irks me. It's unethical to put other people's unpublished work into AI. Journals should not allow it, and reviewers should not do it.

Perhaps I'm late to the party, but you can now feature up to 5 publications on your @orcid.org record 🤩 How to do it: support.orcid.org/hc/en-us/art...

The power of executive coaches in academic medicine career trajectories: hearing from #HeatherBrod heatherbrod.com for our research accelerator (RAPTIC) today tinyurl.com/y58kpdx3 #researchinnovation #coaching #academicmedicine 🧪🧪

Huge congratulations to Gargi Mishra who did a phenomenal job defending her PhD today! Very proud of her many accomplishments in our lab. 🧪🧪

The diversity of adipose functions in health - including nervous system involvement and “adipose neuropathy” - gaining traction in the lay press. Quoted Seely, P Cohen, Me, & Bluher. Great coverage by @newscientist.com #adipose www.newscientist.com/article/2503... 🧪🧪

Great having @drnancypadilla.bsky.social contribute to the series! #neuroskyence

Great piece on #interoception and brain body interactions by @carlzimmer.com in the @nytimes.com www.nytimes.com/2025/11/25/s... What an exciting time to work on this. Join us @cshlmeetings.bsky.social to learn more about the this exciting field meetings.cshl.edu/meetings.asp...

Ohhhh that feeling right before a holiday break when a bunch of papers make it out the lab door, but you also have a stack to peer review yourself, and you just know this universe is connected…. #peerreview #doingmypart 🧪🧪

Big new paper from us published yesterday: The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain www.science.org/doi/10.1126/... Led by @hajisciencebaji.bsky.social in my lab and a wonderful collaboration with Matthew Dalva's lab at Tulane

A great collaborative effort with @zeltserlab.bsky.social and colleagues, now in press, thank you NIDDK! academic.oup.com/edrv/advance...

From your friendly neighborhood SRO: thanks to everyone for their patience while we work to make these rescheduled meetings happen.

Truly enjoyed my time at the Berry Diabetes Center at Columbia this week, delivering a seminar and meeting with colleagues. Great conversations! Thank you to my host @zeltserlab.bsky.social and her lab!

Gotta say, I’m not so confident that you do

Flying Squirrel Loves It Every Time

The world’s coldest microbes are waking up. Warming across the cryosphere — from melting glaciers to thawing permafrost — is accelerating microbial activity, reshaping carbon and nutrient fluxes, and amplifying climate feedbacks (review) www.nature.com/articles/s41...

Found this relic on the “free” table today. Wow would my students laugh to know I used these overhead sheets to complete my PhD comprehensive exam defense. No more “slides” on slide projectors, but we didn’t apparently allow PPT either. 😂😂 The end of an era! 🧪🧪

Another great meeting of the metabolism, obesity, nutrition and diabetes symposium (CDI-MOD) at Michigan this year! Always a friendly crowd and great mix of superb talks. 6 members of our lab, 3 did posters. 🧪🧪

Re-upping link to the starter pack for any who want to follow or be added! #NeuroMetabolism 🧪🧪 go.bsky.app/4nbSbNR

Welcome to Bluesky @zeltserlab.bsky.social !! an important addition to our neurometabolism starter pack

Neuropathy research is essential to reach a cure in our lifetimes. FPN supports research and so much more for the 30mil Americans and 130mil worldwide with this devastating disease. 🧪🧪

Very ready for a long weekend fully UNplugged starting tonight. Let the emails pile up!! My brain needs to blissfully avoid the inbox for a bit. This is your sign to do the same ;) 🧪🧪

Congratulations to Fred Ramsdell, Mary Brunkow and Shimon Sakaguchi - the 2025 Winners of the Nobel Prize in Physiology or Medicine. #Treg_cells #Foxp3 #Immune_regulation

#Throwback 🧪 COMMENT | A brief guide to studying extracellular vesicle function in the context of metabolism C Crewe et al

So well said, both. 🤩

Hahaha yes! But when we don’t have enough food and not obese, a great physiology hack! 🧪

But but. Aren’t ALL these qualities a Type A?

This only happens to you once