New Publication: Targeting Cis-regulatory elements for CRISPR-mediated transcriptional activation of the human MIR503HG locus @edinuni-irr.bsky.social www.sciencedirect.com/science/arti...

New Publication: Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis @uoe-igc.bsky.social www.nature.com/articles/s41...

New Publication: Feline infectious peritonitis epizootic caused by a recombinant coronavirus @roslininstitute.bsky.social @thedickvet.bsky.social @edinuni-irr.bsky.social www.nature.com/articles/s41...

New Publication: Genetic determinants of testicular sperm extraction outcomes: insights from a large multicentre study of men with non-obstructive azoospermia @uoe-igc.bsky.social @jorisveltman.bsky.social academic.oup.com/hropen/artic...

New Publication: Efficient candidate drug target discovery through proteogenomics in a Scottish cohort @uoe-igc.bsky.social @roslininstitute.bsky.social www.nature.com/articles/s42...

New Publication: Genetic score omics regression and multitrait meta-analysis detect widespread cis-regulatory effects shaping bovine complex traits @uoe-igc.bsky.social @roslininstitute.bsky.social academic.oup.com/pnasnexus/ar...

New Publication: Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases @roslininstitute.bsky.social www.nature.com/articles/s41...

New Publication: Polygenic prediction of body mass index and obesity through the life course and across ancestries @uoe-igc.bsky.social www.nature.com/articles/s41...

New Publication: Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI @edinunilbc.bsky.social @edinunineuro.bsky.social @schoolofppls.bsky.social @ukdri.ac.uk @simonrcox.bsky.social www.nature.com/articles/s41...

New Publication: Polygenic Scores of Executive Function Provide Limited Support for Genetic Confounding With Socio-Economic Measures @schoolofppls.bsky.social @drmluciano.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

#GettingGenomeMe Genomics Researcher Profile Dr Amy Findlay is a Postdoctoral Research Associate at The Roslin Institute and Centre for Tropical Livestock Genetics and Health (CTLGH). @roslininstitute.bsky.social @ctlgh.bsky.social onehealthgenomics.ed.ac.uk/amy-findlay

Check out the latest One Health Genomics Edinburgh Newsletter here: mailings.ed.ac.uk/2MP1-22EU9-4...

#GettingGenomeMe Genomics Researcher Profile Dr Mosi Li and his research into the mechanisms of neurodegenerative disease using single cell sequencing and spatial transcriptomics at the Centre for Discovery Brain Sciences. @edinunineuro.bsky.social onehealthgenomics.ed.ac.uk/mosi-li

New Publication: Whole Genome Sequencing of "Mutation-Negative" Individuals With Cornelia de Lange Syndrome @uoe-igc.bsky.social doi.org/10.1155/humu...

New Publication: Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity @thedickvet.bsky.social @uoe-igc.bsky.social @roslininstitute.bsky.social @eduedinburghcrf.bsky.social doi.org/10.1038/s415...

New Publication: The Fortunes of Genomic Medicine: A Quarter Century of Promise @uoe-sps.bsky.social #GenomicMedicine #SociologyofMedicine doi.org/10.1111/ahg....

New Publication: Modeling host-pathway dynamics at the genome scale with machine learning @edinburghbiology.bsky.social #MachineLearning #KineticModels www.sciencedirect.com/science/arti...

New Publication: Combined genomic and molecular analysis defines prognostic markers of relapse in stage IA-IC1 clear cell ovarian carcinoma @uoe-igc.bsky.social #OvarianCarcinoma #MolecularProfiling www.gynecologiconcology-online.net/article/S009...

New Publication: Software Application Profile: TIDAL-Tool to Implement Developmental Analysis of Longitudinal data @edinunineuro.bsky.social #MultilevelGrowthCurveModelling #MillenniumCohortStudy doi.org/10.1093/ije/...

New Publication: Leveraging genome-wide association analyses with chip and imputed data emerges potential pleiotropic region for four duck growth traits @roslininstitute.bsky.social @thedickvet.bsky.social @srucnews.bsky.social doi.org/10.1038/s415...

New Publication: Genome-Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis @uoe-igc.bsky.social doi.org/10.1002/art....

New Publication: Modelling dynamic host-pathway interactions at the genome scale with machine learning @edinburghbiology.bsky.social #MachineLearning #KineticModels #GenomeScaleModels www.sciencedirect.com/science/arti...

New Publication: Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer @uoe-igc.bsky.social pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/...

New Publication: Epigenetic clocks and DNA methylation biomarkers of brain health and disease @uoe-igc.bsky.social @edinunilbc.bsky.social doi.org/10.1038/s415...

New Publication: Evolution and functioning of an X-A balance sex-determining system in hops @edinburghbiology.bsky.social doi.org/10.1038/s414...

New Publication: Environment ensemble models for genomic prediction in common bean (Phaseolus vulgaris L.) doi.org/10.1002/tpg2...

New Publication: Faster adaptation but slower divergence of X chromosomes under paternal genome elimination @edinburghbiology.bsky.social doi.org/10.1038/s414...

New Publication: Microsampling with dried blood spots and mass spectrometry enables PK/PD profiling of responses to praziquantel in a Schistosoma haematobium-exposed Zimbabwean population @uoe-igc.bsky.social @edinburghbiology.bsky.social doi.org/10.1097/fpc....

New Publication: Association between methylation quantitative trait loci and colorectal cancer risk, survival and cancer recurrence @uoe-igc.bsky.social doi.org/10.1038/s414...

New Publication: The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2 @edinburghbiology.bsky.social www.sciencedirect.com/science/arti...

New Publication: Genomics reveals zoonotic and sustained human Mpox spread in West Africa @edinburghbiology.bsky.social @arambaut.bsky.social @aineotoole.bsky.social @ifeanyiomah.bsky.social doi.org/10.1038/s415...

New Publication: Contrasting Evolutionary Trajectories Under Paternal Genome Elimination in Male and Female Citrus Mealybugs @edinburghbiology.bsky.social doi.org/10.1111/mec....

New Publication: A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma @uoe-igc.bsky.social @gerrybrien.bsky.social www.sciencedirect.com/science/arti...

New Publication: Scalable inference of transcriptional variability with BASiCS @uoe-igc.bsky.social @catavallejos.bsky.social www.sciencedirect.com/science/arti...

New Publication: Inherited chromosomally integrated human herpesvirus 6: regional variation in prevalence, association with angina, and identification of ancestral viral lineages in two large UK studies @uoe-igc.bsky.social @genscot.bsky.social @eduedinburghcrf.bsky.social doi.org/10.1128/jvi....

Check out the latest One Health Genomics Edinburgh Newsletter here: mailings.ed.ac.uk/2MP1-229K9-4...

New Publication: Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies @uoe-igc.bsky.social doi.org/10.1111/all....

New Publication: Genomic Analysis of Hair Sheep From West/Central Africa Reveals Unique Genetic Diversity and Ancestral Links to Breed Formation in the Caribbean @thedickvet.bsky.social @roslininstitute.bsky.social doi.org/10.1111/mec....

New Publication: Genome-scale meta-analysis of host responses to Staphylococcus aureus identifies pathways for host-directed therapeutic targeting @edinuni-irr.bsky.social @roslininstitute.bsky.social doi.org/10.1093/infd...

New Publication: Clinical and pharmacogenomic predictors of survival in tamoxifen treated breast cancer female patients: a real-world study @uoe-igc.bsky.social @genscot.bsky.social doi.org/10.1186/s128...

New Publication: The genetic structure and diversity of smallholder dairy cattle in Rwanda @thedickvet.bsky.social @ctlgh.bsky.social @roslininstitute.bsky.social @srucnews.bsky.social @ilri.org doi.org/10.1186/s128...

New Publication: Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification @uoe-igc.bsky.social doi.org/10.1038/s414...

New Publication: Genomics-led approach to drug testing in models of undifferentiated pleomorphic sarcoma @uoe-igc.bsky.social doi.org/10.1002/1878...

New Publication: Understanding Atopic Dermatitis in Asian and European Population Cohorts Using Complementary Omics Techniques @uoe-igc.bsky.social www.sciencedirect.com/science/arti...

New Publication: Evaluating regional heritability mapping methods for identifying QTLs in a wild population of Soay sheep @srucnews.bsky.social @roslininstitute.bsky.social @thedickvet.bsky.social @uoe-igc.bsky.social doi.org/10.1038/s414...

New Publication: Multiomic analysis of human kidney disease identifies a tractable inflammatory and pro-fibrotic tubular cell phenotype @edinuni-irr.bsky.social @uoe-igc.bsky.social doi.org/10.1038/s414...

New Publication: The evolution and convergence of mutation spectra across mammals @roslininstitute.bsky.social @thedickvet.bsky.social @jprendergast.bsky.social doi.org/10.1038/s420...

New Publication: Genetic regulation of gene expression across multiple tissues in chickens @uoe-igc.bsky.social @roslininstitute.bsky.social @thedickvet.bsky.social Read more here: doi.org/10.1038/s415...

#GettingGenomeMe Genomics Researcher Profile Click the link below to find out more about Dr Melissa Marr (@melissamarr.bsky.social) and her research into livestock and endangered species genomics at The Roslin Institute (@roslininstitute.bsky.social‬). onehealthgenomics.ed.ac.uk/melissa-marr

Check out the latest edition of our monthly newsletter for news, events, vacancies and publications from the genomics community at the University of Edinburgh mailings.ed.ac.uk/2MP1-22412-4...