🧬 CAR T cells demonstrate the power of engineered cells as therapeutics. But they fail for most patients. Can CRISPR help here? Our new paper in Nature (www.nature.com/articles/s41...) presents a screening platform to optimize immunotherapies & discover boosters of CAR T cell function. (1/13)

We’re thrilled to announce that the "High-Content CRISPR Screening" conference will take place on March 18–19, 2026, in Vienna, Austria. The registration is now open via the conference website: lnkd.in/d8KACZy5 Meet the Speaker: Christoph Bock @bocklab.bsky.social

🛡️How do macrophages tailor their defenses to different pathogens? Our new paper in @cp-cellsystems.bsky.social combines dense multi-omics time series with high‐content CRISPR screens (CROP-seq) to map the regulatory landscape underlying macrophage immune responses: www.cell.com/cell-systems... (1/9)

🧬How do #macrophages respond so quickly to pathogens? A new study by CeMM & @meduniwien.ac.at researchers, led by @bocklab.bsky.social & @mfarlik.bsky.social, reveals key regulators of immune responses using gene editing & machine learning. ➡️ More info: bit.ly/40p5ABe 🔗 Study: bit.ly/4lwEAIm

🔬 Toward histopathology 2.0: spatial transcriptomes inferred from routine diagnostic H&E images + a chat interface for cell-resolution histopathology through English language. (1/6)

POSTDOC OPPPORTUNITY: We are recruiting via the CeMM postdoc program. Looking for 3 types of candidates: 1. Bioinformatics & systems biology (e.g., immunology, neurobiology or cancer) 2. ML/AI methods for biology & precision medicine 3. Technology development & bioengineering Details below (1/3)

AI in medicine ready for takeoff 🤖🚁 We flew a drone through the Institute of Artificial Intelligence @MedUniWien. Join us for the trip and watch our team at "work". #AI #biomedicine #innovation #makingof (1/2)

AI in medicine ready for takeoff 🤖🚁 We flew a drone through the Institute of Artificial Intelligence @MedUniWien. Join us for the trip and watch our team at "work". #AI #biomedicine #innovation #makingof (1/2)

CeMM's new Research Report is online - a piece of art as always (link below). Each research group selected a mathematical formula that symbolizes their research and visualized it in a live-staged group picture. We picked Shannon entropy, as biomedicine is all about information (and sometimes messy)

Job Posting: Senior NGS Technology & Deputy Head of the Biomedical Sequencing Facility (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences & Medical University of Vienna)

Could a CRISPR screen help you discover new biology? Should you consider high-content readouts such as single-cell or spatial profiling? Check out our methods primer for a hands-on guide (www.nature.com/articles/s43...), co-authored by many experts in the field & now over 225,000 views/downloads.

LAST CHANCE TO APPLY - DEADLINE 21 January 2025

Thrilled to see our work with the @bocklab.bsky.social featured in 'The Scientist'! It's a really great read and builds on an interview I had with the @kamalnahas.bsky.social. www.the-scientist.com/an-ai-lab-pa...

HIRING: We offer several PhD student positions in the CeMM PhD Program. Looking for 3 types of candidates: experimental systems biology in cancer & immunity; bioinformatics & biomedical ML/AI; tech-dev & bioengineering. Join an a highly collaborative lab in molecular medicine. Details below (1/4)

We are recruiting a Tenure-track Assistant Professor "Machine Learning in the Life Sciences" at the Medical University of Vienna. We will nominate the top candidate for a € 1.8 million starting grant by a Viennese foundation. Deadline: Dec 31st. Details: medical-epigenomics.org/files/Tenure...

🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)

We are recruiting a PhD student in ML/AI methods and biomedical applications, within @ELLISforEurope & @humancellatlas. Keywords: Perturbation modeling, generative AI, synthetic biology, cancer immunotherapy, precision medicine. Great environment in Vienna. medical-epigenomics.org/files/PhD_St...

Ready for an expedition into the unknown? We are recruiting two postdocs through the CeMM Postdoc Program. Our group combines ML/AI in bioinformatics, CRISPR & single-cell technology development, and biomedical applications in cancer & immunity. Details: www.cemm.at/fileadmin/us...

Thanks Nature Immunology for highlighting our paper with a Research Briefing, explaining the broader relevance with a bit of backstory and quotes from a reviewer and the editor. The paper is open access, but the Research Briefing is not – please use the following link for free access: rdcu.be/dGnH0

🧬 WHAT KEEPS IMMUNE CELLS AWAKE & ATTENTIVE? It’s their neighbors – stimulation from the tissue environment. We profiled epigenomes & transcriptomes of 12 JAK-STAT mutant mice and found surprisingly strong effects at homeostasis. Paper just out in Nature Immunology: www.nature.com/articles/s41...

Would CRISPR screening help you discover new biology? Check out our methods primer for a hands-on guide (www.nature.com/articles/s43...), co-authored by many experts in the field. Published in 2022, this review has already >150,000 views/downloads (according to the journal). Thank you!

DEADLINE APPROACHING: We are recruiting a Senior Bioinformatician / Biomedical Data Scientist for our research group at the CeMM Research Center for Molecular Medicine & the Institute of Artificial Intelligence of the Medical University of Vienna. Details: cemm.onlyfy.jobs/job/qy9y9wl6

Congratulations @TKrausgruber for the 2023 Science Award of the Austrian Society of Dermatology and Venereology, recognizing our @ImmunityCP paper on sarcoidosis (with Georg Stary): doi.org/10.1016/j.im.... The prize was shared with Harald Kittler for great work on ML-based melanoma diagnostics.

🧬[1/7] Vaccines educate our adaptive immune system, but some also boost innate immunity. We investigated who profits from this “wake-up call” to the immune system, in a prospective clinical study with 323 volunteers. Check out our new paper in @ImmunityCP doi.org/10.1016/j.im...

My pleasure to share the talk videos of the "Convergence? Interfaces of the Digital and the Living" event, exploring five areas: 1 BODIES: Cyborgs abound? 2 BRAINS: Connected mind? 3 CELLS: Homo sapiens 2.0? 4 INTERACTIONS: I you we? 5 CULTURES: For peace and prosperity? tinyurl.com/ConvergenceV...

We are recruiting a Tenure-track Assistant Professor in AI/ML research at the AI Institute at the Medical University of Vienna. We will nominate the top candidate for a € 1.6 million Vienna startup grant. Extra support earmarked for female candidates. Ad: www.medical-epigenomics.org/files/MedUni...

We are recruiting a PhD student for deep learning methods and biomedical applications, within the ELLIS PhD Program & the Human Cell Atlas. Keywords: Causality, perturbation, synthetic biology, cancer, immunotherapy precision medicine. Great environment in Vienna bocklab.org

We are hiring a Senior Biomedical Data Scientist for our lab at CeMM & the Medical University of Vienna. This is a senior staff position within the Bock Lab (bioinformatics, single-cell, CRISPR, cancer), with tenure-track option via @MedUni_Wien . Details: medical-epigenomics.org/files/Senior...

⭕#Convergence? Interfaces of the Digital and the Living The Symposium & Workshop on 17-18 October will explore the links between #informatics and the #lifesciences that are expected to change the way we live and die in the 21st century. Read more! bit.ly/3taVndS

We study cancer and immunology, combining experimental biology with high-throughput technology, bioinformatic methods and machine learning. Our work is interdisciplinary and collaborative. We are equally committed to biological discovery and to advancing medicine.