Great opportunity from the @alzassociation.bsky.social and the Michael J Fox Foundation for early stage investigators whose NIH funding has been disrupted: www.alz.org/research/for... Bravo!

Post your last photo of DC to show what a hellhole it is (Looking down on the carnage)

3. The POs for NIGMS and NIA have been phenomenal (as well as NIBIB, which is an aspiration for us). They have been very calm and reassuring, even as I know that their individual lives are very challenging. We are very lucky to have these staff and should be fighting for them whenever possible. 4/n

As a member of @model-ad.bsky.social it pains me to acknowledge that @niagads.bsky.social won the #AAIC25 swag battle. Well played!

Congratulations to Bruce, wearer of an extra snazzy purple tie today! #EndALZ

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My commitment to equity, diversity and inclusion remains and I hope many will continue to follow regardless of the times

Ok Teams is a disaster but honestly I really like the new Factor 1/Factor 2 review rubric. Much cleaner discussions, more focused on the science and outcomes, and clear boundaries for the SRO/chair to enforce.

The way NIH's Teams meetings sporadically mute audio between random pairs of participants is a marvel of government efficiency. Bravo on the move away from a reliable videoconf platform, a decision I'm sure was made after consulting with the affected CSR staff.

Surprisingly solid pronunciation of Washougal by Phil Liggett #tdf #analysis

The important genetic effects act in trans academic.oup.com/genetics/art...

mad now

Anyone know the appropriate ceremony for the death of a spider that has been living in your sink for the past six weeks? RIP, you

I was just sent this picture of me explaining something to one of the staffers of Representative Suzanne Bonamici (Oregon's 1st congressional district). The thing that impressed me about these congressional staffers is how smart and dedicated they are. I wish we could remove partisan politics.

I taught these cows how to change a flat bike tire. They were very polite.

Rain and fog almost every day in May but at least the granite isn't bare

Met two new calves today, that was nice

Put more effort into making things easier for those below you in the hierarchy than you do for those above you

Flying Delta tomorrow, so excited to see the inside of one of these

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Heritability is easy to systematically underestimate and systematically overestimate, but difficult to pin down. www.medrxiv.org/content/10.1...

TIL I am eligible to become pope. Headed over to Linkedin to start my campaign!

All of the interviews from people who got their jobs in the 1950s-1970s: "My advisor had lunch with his former roommate and said 'Toby's a good fellow.' The next week I packed my bags for New Haven."

🧠 WORKSHOP: Improve the design, execution and analysis of your pharmacokinetic, pharmacodynamic and preclinical efficacy experiments to help #EndALZ. ➡️ Join us in Bar Harbor, Maine, or virtually from May 19 – 23: www.jax.org/education-an...

Me to the IT dept whenever they try to sell me on Copilot

Post a photo you took with no context to bring some zen to the timeline

Punishing the recipients of these awards is of course the intention, and it sucks. What is maybe not so obvious is how damaging this will be to the scientific enterprise.

Be refreshed by this windswept dog on a frozen pond

DEI is the most popular thing in this list lmao

“The connections between Earth science and genomics lie in their shared goal of understanding and unraveling complex systems," says 2023 Raskin Scholar @alexisgarretson.bsky.social. ➡️ Read more about her work in the @jacksonlab.bsky.social: www.esipfed.org/raskin-schol...

2 more open faculty positions (1 TT Asst., 1 TT Assoc./Full) - in Border Studies @sandiegostate.bsky.social, potentially in biology - e.g. cross-border land, resource management, binational biodiversity, transborder ecologies, built environments, sustainable ag, etc.! Links below. Please share!

It was genuinely nice to see familiar NIH program faces on a call today. Weird sentiments for weird times, I guess. 😉

It became clear in the discussion that investing energy in more biologically meaningful ways to embed the data (compared to existing approaches) is likely where comp biologists can have a huge impact with these models. 2/n

Good reminder that although we have fantastic technologies to measure RNA expression, that doesn't mean it's the best indicator of function. www.nature.com/articles/d41...

💡 SPOTLIGHT: Sonal Kumar, a Tufts GSBS Ph.D. candidate in the @gwcarter.bsky.social lab, shares details on her #Alzheimers research, integrating into the research community at @jacksonlab.bsky.social and her future plans. Read more in the Q&A w/ @sonalllk.bsky.social: gsbs.tufts.edu/news-events/...

Want to be more effective in your #Alzheimers Disease (AD) research? Join @model-ad.bsky.social & Sage Bionetworks faculty at @jacksonlab.bsky.social's hands-on Workshop on Computational Techniques for Translational Research in AD to enhance your studies: www.jax.org/education-an... #alzsky

My problem with the Piller article is that by seriously overinflating the consequences of fraud for the field as a whole, the Op-ed becomes nearly as corrosive to science as would understating and covering up the fraud and its consequences.

In my diversity supplement-funded graduate research, I used different types of mice to find DNA regions that alter susceptibility to air pollution. One of these regions is also found in humans and likely influences how severely people with lung diseases are affected by breathing polluted air.

Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-driven β-cell gene expression defects https://www.biorxiv.org/content/10.1101/2025.01.17.633590v1

My avatar was made for David Lynch, who was "hugely American, obsessed with cheese." From Max Evry''s oral history of Lynch's Dune:

Easily the greatest film about cabbages ever made

Wanted my first post to be this work🎉! My break into the single cell🧬 world to understand how anti-ABs affect the brain! What you dont see: the full year of submissions and edits that went into publishing this😅 Thank you @wilcocklab.bsky.social for your support! www.jneurosci.org/content/earl...

My first 2025 opinion is that Africa is the continent with the most appealing shape.

Do you know how to effectively apply multi-scale data to your #AlzheimersDisease research? May 5 – 8, 2025 Gain knowledge & computational techniques at @jacksonlab.bsky.social's workshop: www.jax.org/education-and-learning/education-calendar/2025/05-may/comp-ad?utm_source=bluesky&utm_medium=social

Messing around with an old wheelset and was reminded how much fun it was to keep track of these spacers

Fun problem! Start from Penzance at a heading of 210° and you'll hit NZ after about 20,600 km, just past the antipode.

snowball fight, italy, ca. 1400

Yes but why