New paper out in J Med Chem showing that covalent targeting of C775 has the potential to treat osimertinib resistant lung cancer. Really proud of this work and the team that did it! @nudrugdiscovery.bsky.social @nucancer.bsky.social @crhorizons.bsky.social pubs.acs.org/doi/10.1021/...

New paper: We've always used TPGS in our micellar #DEL synthesis. This paper shows you can find better ones using @baonguyengroup.bsky.social surfactant map. Great work from Jake Odger et al pubs.rsc.org/en/Content/A...

Something makes me think that this invite might have been autogenerated...

It's official, our med chem Senior Research Associate @hannahstewart92.bsky.social is the world's fastest scientist @guinnessworldrecords.com guinnessworldrecords.com/world-record...

Starting the @mosmedcdt.bsky.social conference. It will get better from here!

Group trip to the pub / watch the bins being emptied.

New paper published today describing some SAR on EGFR inhibitors including an interesting effect of a pair of enantiomers on covalent biinding www.nature.com/articles/s42...

Prof. Mike Waring (@mikewaring.bsky.social), Chair of Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky

Nikol Zografou Barredo, PhD Student (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

Dr Hannah Stewart (@hannahstewart92.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

Dr Harriet Stanway-Gordon (@harrietsg.bsky.social), Research Fellow (Medicinal Chemistry/Chemical Biology), Newcastle University #facesofscience #chemsky #sciencesky

Highlighting scientists and the possibility that they may also be humans, give them a follow bsky.app/profile/face...

COMING SOON! Sneak preview of the selection of people we're showcasing this month 🧪

Dr Celine Cano, Reader in Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky

Dr Grace Roper, PDRA (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

Dr Suzannah Harnor (@sjharnor.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky

We have a PhD studentship in the @nudrugdiscovery.bsky.social @chemistryncl.bsky.social with me and @hannahstewart92.bsky.social to develop methods of making macrocycles as a new class of antimicrobial agents. Apply at the link and contact us if you have questions. www.findaphd.com/phds/project...

Check out RSC Medicinal Chemistry now on Bluesky @rscmedchem.rsc.org

Yesterday Julian Knight officially retired from @chemistryncl.bsky.social Julian is a brilliant organic chemistry lecturer and will be sorely missed

Congratulations to Dr Matt Anderson on passing his PhD viva yesterday. @chemistryncl.bsky.social @nudrugdiscovery.bsky.social

We have a #PhDstudentship starting in Sept with me and @hannahstewart92.bsky.social ideal for candidates with interest in research in #medicinalchemistry and #organicsynthesis Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...

Read about our potential breakthrough in oncology - restoring wild type p53 function with ASTX295. This molecule was co-developed with Astex Pharmaceuticals, and is currently showing great phase I trial readout! #cancer #medchem #clinicaltrials www.linkedin.com/posts/cancer...

Our research is critically dependent on funding we receive from @cancerresearchuk.org and we are also willing to do our bit towards fundraising. In 2024: Funds Raised: £6,440 (+£1,031 gift aid) Online Donations: 283 Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz

Exciting collaboration from our @nudrugdiscovery.bsky.social team @newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌

Looking forward to speaking at the #scireviewmeeting next week. Some interesting topics...

@utejungwirth.bsky.social and Kleopatra Papa spoke at this week's BACR New Developments in #BreastCancer Research conference, highlighting their work on the effect of chemotherapy on cancer associated fibroblasts and drug resistance 🧫 @nucancer.bsky.social @crhorizons.bsky.social #cancer #cansky

Our multidisciplinary team, with strong industry links, specialises in structural fragment-based approaches for class-leading cancer drug discovery complemented by our strengths in synthetic chemistry, innovative target validation technologies & hit matter finding. research.ncl.ac.uk/drugdiscovery/

Newcastle Drug Discovery Group arrives on Bluesky bsky.app/profile/nudr...

Looking forward to speaking at this on Tuesday. Apparently they are keen to hear about #fraglites and #dels - we will see www.nepic.co.uk/event/nepic-...

If you or someone you know has stage 4 cancer please take a look at my story and the free resources on www.StriveForFive.org Loads of tips, videos and podcasts. Hope it’s helpful. #stage4 #cancer #RepresentingPatients #Hope

Today's must read from my @cancerresearchuk.org colleague Annalisa Belloni👇 The cost of cancer: what does it mean for the UK economy? news.cancerresearchuk.org/2024/11/21/t...

Thinking of applying to Newcastle for postgraduate study? See details below of an upcoming Postgraduate Virtual Open Day on Wed 27th Nov: www.ncl.ac.uk/study/meet/p...

The Molecular Sciences for Medicine Centre for Doctoral Training is now on Bluesky! We are an EPSRC funded joint venture between Newcastle and Durham Universities aiming to train the next generation of scientists at the interface between chemistry and medicine. 👩‍🔬👨‍🔬🥼🔬🧪 research.ncl.ac.uk/mosmed/