Excited to present our work at #GSA2025: 🧬 “TranslAGE: A Unified Platform to Build and Translate Aging Biomarkers into Clinical Surrogate Endpoints.” Join me at Hynes – Room 306 on Nov 13, 10:00–11:30 AM. Let’s connect and discuss translational aging research!

Presented our work on the bio vs tech reliability of clocks at Harvard’s Biomarkers of Aging Consortium — exploring how biological and technical factors shape aging biomarkers and their clinical use. #Longevity #AgingResearch #EpigeneticClocks #Geroscience

Before Longevity Biotech 2025 kicks off, I sat down with Monty Montano to talk about my journey in aging research and how bridging academia and industry can drive progress in longevity science. #LongevityBiotech #Aging #Epigenetics #Biotech #Healthspan #Research

Thrilled to announce I’ll be speaking at Longevity Biotech 2025 (Boston, Oct 22–23) — many thanks to Longevity Biotech for this opportunity. My session: “Biological vs. Technical Reliability of Epigenetic Clocks & Implications for Disease Prognosis & Intervention Response.”

New episode of Decoding Longevity lands tomorrow! 🧬 We talk to Dr. Iman Azimi about senescent cells, why they aren't all alike, and how his study might reshape how we approach aging with drugs like rapamycin. Hosts: @rvsehgal.bsky.social & Macsue Jacques #Senolytics #Longevity

Grateful to have spoken at #BTBA2025 last week! I shared our work on SystemsAge, which utilizes epigenetic biomarkers to quantify system-specific aging.

🧵 I was recently featured in the @yalecbb.bsky.social BIDS newsletter — sharing reflections on my PhD journey and work in aging science. Here’s a quick recap ⬇️

New drop from Decoding Longevity 🎙️ Peter Fedichev shares why reprogramming isn't enough. Catch it now via @decodinglongevity.bsky.social

Excited to be speaking at BTBA 2025 at Harvard, where I’ll share our recent work on SystemsAge—an AI-driven tool for measuring organ-level aging. #BTBA2025 #SystemsAge #LongevityScience #PrecisionAging #AIinBiotech #HealthyLongevity #HarvardEvents

🧬 New episode: “The Physics of Aging” Guest: Peter Fedichev Hosts: @rvsehgal.bsky.social & Macsue Jacques What if aging is better explained by thermodynamics than biology? 🧵

It’s a mind-expanding convo. Grateful to Peter for joining us 🙏 #LongevityScience #Gero #AgingResearch #Podcast #DecodingLongevity

The @xprize.org Healthspan Summit this week felt like the beginning of something big. Healthy Longevity Clinic (where I’m Director) presented our approach and was selected as one of 40 global semifinalists in the $101M Healthspan Competition.

🎉 We’re semi-finalists in the $101M XPRIZE Healthspan competition! 🚀 Proud to share that Healthy Longevity Clinic is one of just 40 global teams advancing to the next stage, with $250K awarded for a clinical trial to extend healthspan by 20 years. (Safety first!) 👇👇

🎓 After years of research, learning, and growth, I’m thrilled to share my thesis defense as I near the finish line of my PhD journey. Forever grateful to those who’ve supported me along the way. 💫 #YaleGrad #PhDJourney #NewBeginnings

🎙️ New episode! We’re joined by @nireynon.bsky.social ( @monashuniversity.bsky.social ), co-author of “Making sense of the ageing methylome”, to explore what your DNA methylation patterns say about your real biological age. Ep. 4 of Decoding Longevity is now live — don’t miss it!

Back from the A4LI Summit in D.C., where science, policy & innovation came together to reimagine aging. Dr. Mehmet Oz, Eric Verdin & Mike Roizen brought clarity & urgency to the case for healthspan medicine. #A4LI #Longevity #AgingScience

Just saw the new @forbes.com 30 Under 30 Europe list — congrats to all the brilliant minds featured! Grateful to be part of the North America 2025 list myself. Let’s keep raising the bar globally. 🌎✨ #ForbesUnder30 #FutureLeaders #Gratitude

Can we trust current biological age tests? In this reel, Dr. Jesse Poganik explains why most aging biomarkers aren't clinic-ready — and what it takes to get there. 🎧 From Ep. 3 of Decoding Longevity. Now streaming on all major platforms. #longevity #science #biomarkers

🚫 Spoiler: your biological age might not match your birth certificate. In Episode 3 of Decoding Longevity, we talk with Jesse Poganik about how aging biomarkers could help us track and slow the aging process — and why we’re not quite there yet. Now streaming 🎧 #biomarkers #healthspan

🎧 Episode 3 of Decoding Longevity — "How Biomarkers Could Help Us Slow Aging" — is out today! “If you cannot measure it, you cannot improve it.”

Episode 3 of Decoding Longevity drops tomorrow! 🎧 We explore aging biomarkers with our special guest Dr. Jesse Poganik (Harvard Medical School, Biomarkers of Aging Consortium). Big thanks to Jesse for joining us and to the full author team! #Longevity #Biomarkers #AgingResearch>

As the body’s repair systems slow, aging speeds up. These are the final stages: stem cell loss, waste buildup, and gut imbalance. 🎧 Dive into the episode: What is Aging? – Hallmarks of Aging #healthspan #hallmarksofaging #longevity

Aging isn’t always breakdown — sometimes it’s overreaction. This post explains 4 internal changes that go from helpful to harmful. 🎧 Learn more in: What is Aging? – Hallmarks of Aging #longevity #hallmarks #cellularaging

This one explains how aging begins deep inside our cells — in a way that’s easy to understand. 🎧 Listen to the full episode: What is Aging? #longevity #hallmarksofaging #science

Aging starts deep in your cells — long before you see the signs. In our new episode, we explore 3 stages of biological aging: 1️⃣ Primary 2️⃣ Antagonistic 3️⃣ Integrative Start understanding your body on a whole new level. 🎧 Listen to: What is Aging?

What if aging isn’t about “getting old”—but about your body’s systems breaking down over time? In Episode 2 of Decoding Longevity, we unpack the Hallmarks of Aging—updated from 9 to 12 in 2023—and ask: If we know what’s failing, can we fix it? 🎧 Full episode live now! #Longevity #AgingBiology

🎧 Our new episode is live! Raghav & Macsue dive into the Hallmarks of Aging—from the 9 hallmarks described in 2013 to the expanded list of 12 in 2023. What do these updates reveal about how we age? Listen now & share your thoughts in our Spotify poll! #DecodingLongevity #HallmarksOfAging

Can aging smarter fuel a stronger economy? 💡 This week’s podcast dives into how targeting the biology of aging could be the most valuable innovation of our time. 🎧 Now streaming on Spotify. Save it. Share it. Let’s rethink what it means to grow older. #Longevity #Podcast

🎙️ Haven’t listened to Decoding Longevity yet? If you have questions about aging, we’ve got answers! Dive into the science, economics & future of longevity in our first episode. 🔗 Listen now—link in bio! #AgingScience #LongevityPodcast #Healthspan

🎙️ The first episode of Decoding Longevity is now available. ✨ In this episode, Raghav Sehgal and Macsue Jaques discuss the fundamentals of aging and its economic value, breaking down key insights from Scott, Ellison, & Sinclair’s paper, "The Economic Value of Targeting Aging"

🚀 Big news! Our Decoding Longevity podcast launches TOMORROW! 🎙️ We’ll explore how aging science impacts health, economy & the future of longevity research. Get ready for deep insights & expert analysis—don’t miss it! 🔬 #AgingScience #LongevityPodcast #Healthspan

Attending ICFSR 2025 in Toulouse was an inspiring experience! 🌍🔬 Discussing frailty, sarcopenia, and cognitive aging reinforced the importance of early intervention and precision medicine in extending health span. Grateful to Yuta Lee for the photos & Benedicte Clemens for the invite! #ICFSR2025

Heading to ICFSR 2025! I’ll be presenting how epigenetic biomarkers respond to longevity interventions, shedding light on new strategies for frailty & sarcopenia prevention. Looking forward to insightful discussions! #Frailty #Sarcopenia #HealthyAging #Biomarkers #Geroscience

Excited to join the Pre-Clinical & Clinical Geroscience Task Force in 🇫🇷 Toulouse on March 11, 2025! I'll present: 🧬 Mapping the Responsiveness of 100+ Epigenetic Biomarkers Across 50+ Anti-Aging Interventions Looking forward to great discussions on translational geroscience! #Longevity

Proud to officially be Dr. Sehgal! 🎓 After years of research and dedication, I successfully defended my PhD thesis on Translating Geroscience to Clinic. Grateful to my mentors and colleagues for their support. Excited for the next chapter in longevity science! 🚀 #PhDDefense

Saying hello to Bluesky with an exciting milestone! On Feb 27, I’ll be defending my PhD thesis: Translating Geroscience to Clinic - Using ML for Aging Biomarkers. Excited to discuss how biomarker-driven strategies can bridge aging research & clinical applications! #Geroscience #ML #AgingResearch