Christopher Torrens
@christophertorrens.bsky.social
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📥 34
📝 62
Rhyming off physiology facts for everyone
That beta-adrenoceptors mediate dilatation. Does not mean that they’re inhibitory. Just like the rest, They’re linked to G alpha S, So result in more cyclic AMP.
3 months ago
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Trapped in the freshly laid osteoid, Some osteoblasts become osteocytes. There they sense load, Such that remodelling is slowed, In the immobile and also spaceflight.
4 months ago
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So that’s an end of this year’s daylight savings. It is not just an extra hour in bed. Disruption ensues, To your Zeitgeber cues, Increasing risk from chronic diseases instead.
4 months ago
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Smooth muscle is the best type of muscle, For all of the roles that it plays. From controlling blood flow, To when you must go, And your focus, peristalsis and airways.
4 months ago
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Isometric or isotonic contractions, Are used for muscle experimenting. Isometric depends, On being secured at both ends, And where tension’s developed but not shortening.
5 months ago
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The sacroplasmic reticulum, Is a skeletal muscle calcium store. Following depolarisation, The T-tubule migration, Stimulates ryanodine receptors and the outpour.
5 months ago
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The humble Valsalva manoeuvre, Can test autonomic control. The quickened pulse it reflects, The baroreceptor reflex, That’s triggered by the subject’s breath hold.
5 months ago
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With colds and with flu comes a fever, As pyrogens act from within. Your hypothalamus is told, That you’re actually cold, So physiological thermogenesis kicks in.
6 months ago
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Once acetylcholine binds to its receptor, And its target cell signal transduced. The cholinesterase, Ensure it never outstays, And what’s left in the cleft is reduced.
6 months ago
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Lactate ringers in hyperkalaemia, Was once contraindicated. As potassium it contains, A fear of adding fuel to the flames, So saline was preferred option instead.
6 months ago
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Intermittent claudication, A hallmark of arterial disease. From the pain you imply, Demand can’t be met by supply, But if you stop for a rest it will ease.
7 months ago
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The thing about catecholamines, Is their rank order of potency. Adrenaline it’s true, Binds both alpha and beta too, But it’s beta it’ll bind preferentially.
7 months ago
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Contusion or trauma to the testicles, Can be felt in the lower abdomen. That pain is referred, By the genitofemoral nerve, Which arises from the spinal lumbar region.
7 months ago
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Interactions between pure actin and myosin, Aren’t regulated but actually the norm. But on filaments that are thin, The tropomyosin, Regulates when cross bridges will form.
7 months ago
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The phenomenon of the pudding stomach, To squeeze in dessert even though you’re full. Having dined out on salty, And a helping of umami, Something sweet offers a tasty new pull.
7 months ago
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As temperatures climb in a heatwave, And you look for some protection. One way to keep cool, Put your feet in a basin or pool, As it increases heat loss by convection.
8 months ago
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A crucial survival mechanism, Is the flexor withdrawal reflex. Noxious sensory information, Has rapid spinal integration, And sharp withdrawal avoids harmful effects.
8 months ago
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The joys of small vessel myography, When you don’t know whether to cry or to laugh. When the vessel’s prepared, With the upmost of care, Only to disappear, without trace, in the bath.
8 months ago
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An osteoblast will lay down the osteoid, Within this freshly laid bone some remain. That’s not the end of its plight, It becomes an osteocyte, And relays signals of bone stress and strain.
8 months ago
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The ventricular action potential, Has a long phase of calcium plateau. Because it’s still depolarised, The heart can’t be tetanised, As the tension on its way to zero.
8 months ago
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Secondary hyperparathyroidism, Is a feature of chronic kidney disease. With the tissue depletion, There’s less 1 alpha hydroxylation, Resulting in vitamin D deficiencies.
9 months ago
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BNP is a marker of heart failure, That suggests excess fluid retention. Since the Frank-Starling curve, Says stroke volume’s preserved, By a RAS-induced volume expansion.
9 months ago
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Filtration along a capillary, Is not reversed at the venous ends. In the interstitium’s place, Sits the subglycocalyx space, That’s the gradient upon which filtration depends.
9 months ago
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A protection for cerebral perfusion, Alpha adrenoceptors are relatively rare. So when sympathetic activation, Produces peripheral constriction, The cerebral circulation is relatively spared.
9 months ago
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In the principal cells of the kidney, Are important for sodium reabsorption. But this comes at a cost, That is potassium loss, So you can’t control either in isolation.
10 months ago
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The mechanism of reactive hyperaemia, Increased flow after a drop in perfusion. As flow increase from its nadir, There’s an increase in shear, The results in more vasodilation.
10 months ago
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Glycine is a neurotransmitter, That results in an IPSP. Chloride influx will swell, Hyperpolarising the cell, And the further from the threshold it’ll be.
10 months ago
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A neuron is not like a muscle, Where it fires from each stimulation. The channels are voltage-gated, So stimuli must be summated, To build up enough excitation.
10 months ago
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Efficient gas exchange happens, When ventilation and perfusion align. Where ventilation is poor, Vasoconstriction occurs, Redistributing blood where it’s fine.
10 months ago
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Lead I and II should be positive, So if lead I has inverted on sight. The axis you see, Is not where it should be, As it has deviated off to the right.
11 months ago
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Current flows away from dead tissue, To healthy tissue from that that’s infarcted. So when the heart is at rest, The ECG trace is depressed, But when depolarised it appears that it’s elevated.
11 months ago
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Hypoxic pulmonary vasoconstriction; Important in development, not just disease. With the first breath after birth, Fetal shunts will reverse, As pulmonary resistance and pressure decrease.
11 months ago
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An eGFR is convenient, But if it’s accuracy you want, then alas. An interpretation of filtration, From a plasma creatinine concentration, Requires some assessment of mass.
11 months ago
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Poor perfusion occurs in angina, Where coronary arteries have been narrowed. Its treatment, as planned, Effects not supply but demand, Via the reduction in cardiac workload.
12 months ago
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Across the cardiac cycle, The blood pressure waxes and wanes. But the blood pressure mean, Is not halfway between, As the time in each phase ain’t the same.
12 months ago
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The fetal response to acute hypoxia, Has two actions in the main. Femoral vasoconstriction, And cerebral vasodilation, That redistributes blood to the brain.
12 months ago
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A fabulous inaugural lecture. A greengrocer? What could have been? But you were physiologically inclined, So our paths intertwined, Congratulations Prof Lucy Green
@looceegreen.bsky.social
about 1 year ago
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When ascending from a deep water dive, The ascent should be managed in stages. Because when the pressure’s relieved, The gas bubbles are freed, And will lodge in inopportune places.
about 1 year ago
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When giving your valentines card, To the eyes look hard, For signs of pupil dilation. For the feeling of love, When push comes to shove, Contains components of sympathetic activation.
about 1 year ago
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Oxy-haemoglobin is red, While deoxy is blue. When saturation is low, Cyanosis you’ll view.
about 1 year ago
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Potassium loss with loop diuretics, Isn’t due to inhibition in ascending limb. Instead the sodium swell, At the principal cell, Drives potassium loss from within.
about 1 year ago
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Nitrates for use in angina, Don’t dilate the arteries that are stenosed. Through systemic dilation, They reduce oxygen consumption, By reducing the overall workload.
about 1 year ago
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Surrounding a burn there’s inflammation, And factors causing vasoconstriction, That results in reduced perfusion, And transudate. Necrosis or recovery an option? Either fate. Happy Burns Night
about 1 year ago
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The threshold of an action potential, Is because of the voltage-gate. Once the threshold’s attained, The activation gate in unchained, And the channels transform to their “active” state.
about 1 year ago
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Cold-induced peripheral cyanosis, Is a result of vasoconstriction. This produces sluggish flow, Meaning perfusion is low, Which results in a low saturation.
about 1 year ago
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In mammals the advantage of fur, Is to trap a layer of warm air. In humans this piloerection, Helps thermoregulation, Even though the fur is no longer there.
about 1 year ago
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Alcohol is a mild diuretic, That produces increased urine flow. So a night on the sauce, Leads to increased fluid loss, Giving rise to a hangover don’t you know.
about 1 year ago
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Once past the winter solstice, And the days they start to expand. The day/night cycle it shifts, By the suprachiasmatic nucleus, Controlled in turn by the pineal gland.
about 1 year ago
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The equilibrium potential of sodium, Doesn’t determine the action potential peak. Although there’s free sodium entry, It falls short just slightly, Because potassium still continues to leak.
about 1 year ago
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reposted by
Christopher Torrens
Triona NĂ Chonghaile
about 1 year ago
Huge congratulations to the newly minted Dr. Andy Roe on his viva 🎉!! Thanks so much to examiners
@crismunozp.bsky.social
and Dr. Niamh Connolly (not on Blue sky!) and the chair
@christophertorrens.bsky.social
@rcsi.bsky.social
@rcsi-research.bsky.social
. Looking forward to following your đź’« career.
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