CFlores-Lab
@labcflores.bsky.social
📤 22
📥 65
📝 58
Passionate scientists leveraging genomics to understand diseases and seeking clinical applications
reposted by
CFlores-Lab
Don't miss the opportunity to read it!
www.thelancet.com/journals/lan...
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Rare variants and survival of patients with idiopathic pulmonary fibrosis: analysis of a multicentre, observational cohort study with independent validation
We found non-additive effects between qualifying variants and common risk variants in IPF survival, suggesting distinct disease subtypes and raising the possibility of using PRS to guide sequencing pr...
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00045-1/fulltext
7 days ago
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reposted by
CFlores-Lab
Delighted to share that one of our studies in
#IPF
has been highlighted by
@rachelnuwer.bsky.social
in
@nature.com
among the six highlights from lung health research.
www.nature.com/articles/d41...
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Six highlights from lung-health research
Fibrosis survival, long COVID’s lasting toll and other highlights from lung studies.
https://www.nature.com/articles/d41586-026-00111-z
7 days ago
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Delighted to share that one of our studies in
#IPF
has been highlighted by
@rachelnuwer.bsky.social
in
@nature.com
among the six highlights from lung health research.
www.nature.com/articles/d41...
loading . . .
Six highlights from lung-health research
Fibrosis survival, long COVID’s lasting toll and other highlights from lung studies.
https://www.nature.com/articles/d41586-026-00111-z
7 days ago
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reposted by
CFlores-Lab
Adrián Gómez
9 days ago
I am deeply grateful to my supervisors @ciuffreda_lau and
@labcflores.bsky.social
for their guidance; to my collaborators, for the teamwork and the funding bodies for supporting this work.
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Respiratory syncytial virus
#RSV
is the leading cause of acute lower respiratory tract infections in children <2 years. It can also severely affect adults. Since the introduction of a prophylactic mAbs treatment in Spain, resistant
#RSV
lineages have been reported.
9 days ago
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Acute respiratory distress syndrome
#ARDS
is a critical condition characterized by respiratory failure, an acute inflammatory response, and the development of non-cardiogenic pulmonary edema. Sepsis is one of the leading causes of
#ARDS
and has a high mortality ICUs.
15 days ago
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Paper alert! Happy for our contribution to another
#GIAB
resource paper.
#ITER
@labcflores.bsky.social
www.cell.com/cell-genomic...
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Characterization of subclonal variants in HG002 Genome in a Bottle reference material as a resource for benchmarking variant callers
Daniels et al. extended the Genome in a Bottle HG002 characterization to include subclonal variants, enabling the development of a new benchmark set for evaluating somatic and mosaic variant calling m...
https://www.cell.com/cell-genomics/fulltext/S2666-979X(25)00360-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2666979X2500360X%3Fshowall%3Dtrue
about 2 months ago
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Looking for a professional opportunity in Tenerife contributing to the largest cohort study so far being built in the country? Want to join the
#cohorteimpact
project?
cohorte-impact.es
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Cohorte Impact
Si te han seleccionado para participar en el estudio, recibirás una llamada desde tu Centro de Salud. En el proyecto trabajan excelentes profesionales sanitarios que te explicarán en qué consiste formar parte de la Cohorte. ¡No dudes en unirte a este gran proyecto!
https://cohorte-impact.es/
about 2 months ago
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Preprint alert! Many studies have established the grounds to increase the diversity in catalogs of genetic variation to optimally represent population-specific particularities and to support Personalized Medicine strategies across populations worldwide.
2 months ago
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Paper alert! Immunocompromised patients could suffer a SARS-CoV-2 infection with viral shedding for long periods of time. Sequencing on serial samples of the patient previously evidenced accelerated viral evolution with accumulation of mutations.
www.journalofinfection.com/article/S016...
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Longitudinal study of a SARS-CoV-2 infection in an immunocompromised patient with X-linked agammaglobulinemia
In this journal, Walsh and colleagues1 recently reviewed the evidence supporting that immunocompromised patients may remain positive for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in...
https://www.journalofinfection.com/article/S0163-4453(21)00373-X/fulltext
3 months ago
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Today was another great day for
@labcflores.bsky.social
. We have a new Doctor in town. Kudos
@evatosco.bsky.social
for such a fantastic defense of your PhD. Hope you enjoyed the day despite the nerves of these past months. Glad to share some of the best moments of the day.
3 months ago
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Very grateful for the invitation to talk in the World Critical Lung Day (IX Edition;
wdcl.com.co
) organized by
#Fepimcti
to share the state-of-the-art in genomics to better characterize infections and how our team leverage these technologies for better care.
3 months ago
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reposted by
CFlores-Lab
European Journal of Human Genetics
3 months ago
📢 WES and telomere analyses in idiopathic pulmonary fibrosis
#IPF
patients uncovered pathogenic RTEL1 and NAF1 variants through a robust, clinically useful tiered virtual gene panel workflow. 🧬 Read more in the latest issue of
#EJHG
⬇️
www.nature.com/articles/s41...
add a skeleton here at some point
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We are delighted to announce that one
@labcflores.bsky.social
study led by
@aitanaag90.bsky.social
has received the Award "II Premios Canarias a la Ciencia de la Salud e Investigación Biomédica" for the best scientific publication of the year. Link to the paper:
www.thelancet.com/journals/lan...
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Rare variants and survival of patients with idiopathic pulmonary fibrosis: analysis of a multicentre, observational cohort study with independent validation
We found non-additive effects between qualifying variants and common risk variants in IPF survival, suggesting distinct disease subtypes and raising the possibility of using PRS to guide sequencing pr...
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00045-1/fulltext
3 months ago
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Delighted to share that our manuscript entitled “A tiered strategy to identify relevant genetic variants in familial pulmonary fibrosis: a proof of concept for the clinical practice” is now published in the
@ejhg-journal.bsky.social
November issue
3 months ago
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reposted by
CFlores-Lab
Adrián Gómez
3 months ago
I am grateful to CIBERES and CIBERBBN for organizing such an enriching meeting, and to all funding bodies, institutions, and collaborators who made this work possible.
@ciberisciii.bsky.social
@labcflores.bsky.social
#CIBERES
#CIBERBBN
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reposted by
CFlores-Lab
Adrián Gómez
3 months ago
Our findings highlight a set of proteins involved in immune regulation and tissue remodelling, which may shed light on the mechanisms driving long-term lung sequelae.
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reposted by
CFlores-Lab
Adrián Gómez
3 months ago
In this study, we explored whether plasma protein levels measured six months after ICU discharge could serve as biomarkers of interstitial lung disease (ILD) in patients who survived a severe COVID-19.
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reposted by
CFlores-Lab
Adrián Gómez
3 months ago
During the event, I presented our work titled: “Interstitial lung disease protein biomarkers in post-COVID patients.”
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reposted by
CFlores-Lab
Adrián Gómez
3 months ago
Last week, I had the pleasure of attending the Jornadas de Personal Investigador Joven CIBERES–CIBERBBN 2025, an inspiring meeting that brought together young researchers from across Spain to exchange ideas, projects, and challenges in biomedical research.
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It's been an intense week for us with several of our study results being presented at different research gatherings
3 months ago
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reposted by
CFlores-Lab
Antimicrobianos Hub CSIC
3 months ago
🌎La resistencia a los antimicrobianos es una amenaza a escala global. 🤝En Conexión-AMR tenemos claro que este reto solo puede enfrentarse desde múltiples perspectivas y colaborando entre disciplinas. (1/2)
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reposted by
CFlores-Lab
Sara Cuevas Ocaña
3 months ago
What a nice conference with such inspiring speakers
@kottond.bsky.social
@francypolverino.bsky.social
@jennydickens41.bsky.social
Really enjoyed meeting old and new people in the genomics space! Looking forward to the foreseeable progress in the field
#RespGen25
add a skeleton here at some point
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Happy to share our results and an update of the genetic studies in
#ILD
in this meeting.
@labcflores.bsky.social
4 months ago
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By now, it would not surprise anyone to understand that there are host genetic variants governing severe infection outcomes.
4 months ago
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reposted by
CFlores-Lab
Want to better understand what interstitial lung diseases are and what do we aim for with the project PRECISION-ILD funded by
@isciiisalud.bsky.social
involving the participation of many researchers from Spain and abroad? Check the project's webpage:
precisionepid.com
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Precision-ILD
https://precisionepid.com
5 months ago
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Want to better understand what interstitial lung diseases are and what do we aim for with the project PRECISION-ILD funded by
@isciiisalud.bsky.social
involving the participation of many researchers from Spain and abroad? Check the project's webpage:
precisionepid.com
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Precision-ILD
https://precisionepid.com
5 months ago
0
2
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