Marek van Oostrom
@marekvanoostrom.bsky.social
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PhD candidate in the Sonnen group at the Hubrecht Institute, Utrecht, The Netherlands.
reposted by
Marek van Oostrom
Ina Sonnen
5 months ago
Using fluorescence live imaging and an in vitro implantation model, we show that human embryo attachment begins with direct cell fusion via syncytin-2–MFSD2A interaction. With
@hansclevers.bsky.social
. Great work by
@tnoordzij.bsky.social
&
@martinacelotti.bsky.social
www.biorxiv.org/content/10.6...
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reposted by
Marek van Oostrom
Campàs Lab
7 months ago
Really excited to present the results of a fantastic collaboration with Jesse Veenvliet
@jesseveenvliet.bsky.social
@mpi-cbg.de
@poldresden.bsky.social
🤩 We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species ➡️
www.biorxiv.org/content/10.1...
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reposted by
Marek van Oostrom
Ina Sonnen
9 months ago
Preprint alert! We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
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reposted by
Marek van Oostrom
Development
about 1 year ago
In preprints: robust segmentation clock outputs via cell cycle and synthetic coupling Here,
@jorgelazaro.bsky.social
and
@ebisuyamiki.bsky.social
discuss two
#preprints
looking into the mechanisms regulating somitogenesis through cell- and tissue-level couplings:
doi.org/10.1242/dev....
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reposted by
Marek van Oostrom
Ina Sonnen
about 1 year ago
How do embryos ensure precise tissue patterning? It’s all about timing cell divisions! Our new preprint reveals how cell proliferation syncs with signaling oscillations to regulate precision of somite formation and growth. Check the full story:
www.biorxiv.org/content/10.1...
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