Mark A Rubin
@marubin1.bsky.social
📤 42
📥 8
📝 4
Precision Oncology researcher in Switzerland with special interest in epigenetics and splicing.
reposted by
Mark A Rubin
DBMR University Bern
13 days ago
New
@natmed.nature.com
News & Views by
@marubin1.bsky.social
and Dr. Irene Paassen on why
#PrecisionOncology
must go beyond genomics.
@medfacultyunibe.bsky.social
@pmbern.bsky.social
tinyurl.com/2zvdvmy6
0
5
3
reposted by
Mark A Rubin
ESMO - European Society for Medical Oncology
about 1 month ago
📣 Updated ESMO #ClinicalPracticeGuideline on local & locoregional #ProstateCancer: ✅New imaging modalities: Improved diagnosis, staging & risk stratification ✅Updated algorithms: less over-Tx & fewer side-effects #Oncology #UroOncology #CancerCare #ESMOGuidelines 🔗
https://ow.ly/jwA650XLs1q
1
10
4
Excited to share new preprint on the minor spliceosome in cancer! Targeting U6atac disrupts DNA repair and sensitizes prostate & breast tumors to radiation, cisplatin and PARP inhibitors—even beyond BRCA-mutant .
bit.ly/48RnsI5
#DNARepair
#ProstateCancer
#BreastCancer
#U6atac
@theaacr.bsky.social
about 1 month ago
0
0
1
Congrats to Jia and Michael and team. This has been a major effort and we are learning so much about lineage plasticity
www.nature.com/articles/s41...
.
loading . . .
NSD2 targeting reverses plasticity and drug resistance in prostate cancer - Nature
Inhibition of the histone methyltransferase NSD2 and the androgen receptor in preclinical models can reverse lineage plasticity to suppress tumour growth and promote cell death in multiple subtypes of...
https://www.nature.com/articles/s41586-025-09727-z
about 2 months ago
0
0
1
www.nytimes.com/interactive/...
loading . . .
How Trump’s Medical Research Cuts Would Hit Colleges and Hospitals in Every State
Changes to a key funding formula will reduce research grants at hospitals and universities by billions — and may discourage future research.
https://www.nytimes.com/interactive/2025/02/13/upshot/nih-trump-funding-cuts.html?smid=nytcore-ios-share
11 months ago
0
0
0
I Used to Run the N.I.H. Here’s What Worries Me.
www.nytimes.com/2025/02/14/o...
loading . . .
Opinion | American Science is Under Attack
The Trump administration hobbles research and endangers the public health.
https://www.nytimes.com/2025/02/14/opinion/trump-public-health-funding-nih.html?smid=bs-share
11 months ago
0
1
0
you reached the end!!
feeds!
log in