Immune response following blood infection from Salmonella exposure (green dots 🟢) in a live zebrafish larva. Credit to @margaritapk.bsky.social. #ZebrafishZunday 🧪

Optogenetic mediated contractility enables reversible control of microglial morphology and migration in vivo

Zaza’s main PhD work just came out in a journal! Macrophage cell nuclei physically sense 50 um/s fast osmotic shock waves coming from wounds to mediate rapid vessel permeabilization and serum exudation - one of the hallmarks of acute inflammation. www.nature.com/articles/s41...

Very happy to share this study from our group and colleagues now out in Science! We found that in zebrafish, before the immune system is mature, gut epithelial cells perform immune functions by producing the cytokine IL-22 to shape the microbiota to promote early life gut function #Zebrafish #Gut

Exactly two years ago we wrote a review on wound healing, but at the time it was posted in the site that shall not be named, so check out here if your favourite cell was featured, and leave a complaint here if I missed it 😅 www.nature.com/articles/s41...

Excited to have started my new lab in Human Genetics at Pitt Public Health! We study wound healing in diabetes & aging using adult zebrafish. Check out this movie showing neutrophil dynamics after injury. Now recruiting research staff, grad students, and postdocs. DM me if interested.

Our new paper on valve disease in aged #zebrafish is out! onlinelibrary.wiley.com/doi/10.1111/... This has been a long running collaborative effort with contributions from lots of great people!

I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟 www.sciencedirect.com/science/arti... Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....

Great article by @kordinglab.bsky.social‬ on "why causal knowledge is pragmatically possible". The best arguments for causation--& only one we need--is pragmatic. Here pragmatic isn't weak/subjective, but connected to actual goals, utility & outcomes in the world. medium.com/@kording/why...

Our paper has now been published @elife.bsky.social 🎉🎉🎉 Check it out, especially if you are interested in the TCR repertoire and T cell development in the thymus doi.org/10.7554/eLif...

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

Do you work in #DevBio and want to introduce the fascinating world of developmental biology to your family and friends? You can show them this science documentary, produced by the British Society for Developmental Biology, The Company of Biologists and Cambridge Filmworks! 📽️ youtu.be/avrmIs3vPUQ?...

Scientists of any gender working in female-dominated disciplines receive lower scores during evaluation and are less likely to get funded. elifesciences.org/digests/9761...

Live imaging of zebrafish embryos reveals early differences in the genesis of the cells that become blood and immune cells, shedding light on how these precursors emerge from vessels. elifesciences.org/digests/9142...

Any #zebrafish friends still swimming around on here? We’d love to follow you! #ThatsHowWeShoal

For those who might be interested: We discovered a novel molecular pathway that links #tryptophan metabolism and glutamate #kainate receptors (KAR) to resistance against lethal #bacterial infections in zebrafish. www.biorxiv.org/content/10.1... Please RT!