Francesco Cardamone
@francescocardamone.bsky.social
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PhD Student at Iovino Lab, Max Planck Institute of Immunobiology and Epigenetics.
reposted by
Francesco Cardamone
Job Dekker
19 days ago
A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists!
www.nature.com/articles/s41...
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An integrated view of the structure and function of the human 4D nucleome - Nature
The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...
https://www.nature.com/articles/s41586-025-09890-3
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Francesco Cardamone
eric lai
2 months ago
🪰 folks! I spoke to the Transmitter about FlyBase. As noted at
flybase.org
, bridge $ ran out and many staff were laid off. Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
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FlyBase secures funding for year, but future still uncertain
The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.
https://tinyurl.com/FlyBase
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Francesco Cardamone
Nature
3 months ago
Obituary: John Gurdon (1933-2025) Biologist who made cloning possible
go.nature.com/3WicRAe
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John Gurdon obituary: Biologist who made cloning possible
He showed that specialized cells retain the genes to form an organism.
https://go.nature.com/3WicRAe
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Feeling inspired after presenting some
#3Dgenome
&
#single-cell
data at the
#EDRC2025
in the beautiful
#Alicante🇪🇸🧬🪰
Looking forward to the next amazing sessions to exchange ideas and connect with the community!
3 months ago
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Functional maps of a genomic locus reveal confinement of an enhancer by its target gene | Science
www.science.org/doi/10.1126/...
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Functional maps of a genomic locus reveal confinement of an enhancer by its target gene
Genes are often activated by enhancers located at large genomic distances, and the importance of this positioning is poorly understood. By relocating promoter-reporter constructs into thousands of alt...
https://www.science.org/doi/10.1126/science.ads6552
3 months ago
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reposted by
Francesco Cardamone
Alexis Verger 🧬🧫🧪
4 months ago
If you like transcription regulation and its mechanisms, this WIP list is for you. I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list.
go.bsky.app/8vTgeXB
add a skeleton here at some point
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reposted by
Francesco Cardamone
Darío Lupiáñez
6 months ago
How bats developed their wings? 🦇 Turns out they reutilize existing gene programs 🔧 Find out more in our paper
@natecoevo.nature.com
in collaboration with
@fany-real.bsky.social
and
@stemundi.bsky.social
labs
www.nature.com/articles/s41...
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Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development - Nature Ecology & Evolution
Single-cell comparison of developing bat and mouse limbs reveals conservation of cell populations and gene expression patterns, and suggests repurposing of genes involved in proximal limb development ...
https://www.nature.com/articles/s41559-025-02780-x
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Francesco Cardamone
Arantxa Rojas
7 months ago
Our News&views with Germano
@cecerelab.bsky.social
about the role of H3K27me3 in epigenetic control of piRNA transcription in worms 🪱 and flies 🪰 is out in
@natsmb.nature.com
rdcu.be/erkld
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H3K27me3 expands the epigenetic control of piRNA transcription
Nature Structural & Molecular Biology - Constitutive heterochromatin can promote piRNA transcription, a crucial step in genome defense. Two studies now show that piRNA transcription in...
https://rdcu.be/erkld
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reposted by
Francesco Cardamone
Axel Visel
7 months ago
Textbooks: “Enhancers are just a bunch of TFBSs” But how do they REALLY work? New paper with many contributors here
@berkeleylab.lbl.gov
,
@anshulkundaje.bsky.social
,
@anusri.bsky.social
A 🧵 (1/n) Free access link:
rdcu.be/erD22
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reposted by
Francesco Cardamone
Max Planck Institute of Immunobiology and Epigenetics
7 months ago
👀 New study: The stability of circular RNAs makes them ideal for long-lasting regulatory tasks in neurons. Researchers from the
@hilgerslab.bsky.social
have now identified the protein ELAV protein as a master regulator of circular RNA production in the nervous system, crucial for brain function.
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Running circles in my head
Researchers in Freiburg have identified the protein ELAV as a key regulator of circular RNA production in the nervous system, which is crucial for brain function.
https://www.ie-freiburg.mpg.de/6041616/news_publication_24855497_transferred?c=4686940
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reposted by
Francesco Cardamone
Max Planck Institute of Immunobiology and Epigenetics
8 months ago
The next TriRhena Gene Regulation Club takes place at the MPI-IE
#Freiburg
. Save your seat & submit a talk. Strengthen your local
#epigenetics
network & collaborate with peers. 📅 16 Jun 2025 | 14:00 🎟️ Free entry, registration required ✍️ Register by: 6. Jun
www.ie-freiburg.mpg.de/gene-regulat...
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reposted by
Francesco Cardamone
Max Planck Institute of Immunobiology and Epigenetics
9 months ago
Interested in the latest advancements of
#epigenetics
of
#mammalian
early embryogenesis? Then join our upcoming mini-symposium in Freiburg! 📅 April 24, 2025, 14:00-19:00 PM 📌 Max Planck Institute, Freiburg (only on-site!) 🛠️ Organized by:
@iovino-lab.bsky.social
Register & join free of charge.
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Symposium: Epigenetics of early mouse development
We are delighted to invite you to to the second symposium, “Epigenetics of Early Mouse Development”, taking place on April 24, 2025, at the Max Planck Institute of Immunobiology and Epigenetics in Fre...
https://www.ie-freiburg.mpg.de/events/41595/4678708
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reposted by
Francesco Cardamone
Iovino-Lab
9 months ago
Exciting news! Our latest work in the Nicola Iovino Lab, “Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis,” is now published in Nature Communications!
www.nature.com/articles/s41...
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Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis - Nature Communications
Germ layer specification during zygotic genome activation is regulated by chromatin state. Here, the authors use single-cell multiome profiling in Drosophila to show that H3K27me3 and H3K27ac at cis-r...
https://www.nature.com/articles/s41467-025-57719-4
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About a week ago, our new story in the
#IovinoLab
about chromatin factors and germ layer specification during ZGA in Drosophila embryos was published! Missed it? 🔎 Check out this resume article by our Institute!
#chromatin
#epigenetics
#development
add a skeleton here at some point
9 months ago
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Amazing piece of work from
@ninacabezas.bsky.social
Lab! Congratulations Jasmin, Mari & team!
add a skeleton here at some point
9 months ago
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