Iovino-Lab
@iovino-lab.bsky.social
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Epigenetic Inheritance
🔍 Curious about your favorite gene’s expression in single-cell Drosophila embryos? Try our interactive Shinyapp:
iovinolab.shinyapps.io/scmultiomeZGA/
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scMultiome ZGA Feature of Interest Coverage Plot About
scMultiome ZGA is an online web application to explore the transcriptome and chromatin accessibility of the ZGA Drosophila embryo at single cell resolution, supporting the following publication:
https://iovinolab.shinyapps.io/scmultiomeZGA/
5 months ago
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Exciting news! Our latest work in the Nicola Iovino Lab, “Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis,” is now published in Nature Communications!
www.nature.com/articles/s41...
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Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis - Nature Communications
Germ layer specification during zygotic genome activation is regulated by chromatin state. Here, the authors use single-cell multiome profiling in Drosophila to show that H3K27me3 and H3K27ac at cis-r...
https://www.nature.com/articles/s41467-025-57719-4
6 months ago
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