Can proteins fold and function with half of the amino acid alphabet? Using only 10 residues, we designed stable, mutation-resilient structures—no aromatics or basics involved. A minimalist foundation for ancient biology and synthetic design. tinyurl.com/37t8br4v #ProteinDesign #OriginsOfLife

22nd Structural Biology Club online on 26th November 2025, 1pm CE: Structures in solution: BioSAXS at BM29 ESRF by Petra Pernot & Cryo-EM data processing in CCP-EM Doppio by Colin M. Palmer cssb.structbio.org/22nd-structu...

Homology modeling

Protein Production Hands-On Workshop Dates: December 2 – 4, 2025 Venue: BIOCEV, Vestec Registration Deadline: October 31, 2025 Cost: Free of charge (accommodation not included) Registration Link: forms.biocev.org/index.php/14... Workshop Page: www.ibt.cas.cz/en/core-faci...

Our first protein design paper out in Protein Science onlinelibrary.wiley.com/doi/10.1002/...

Pranam Chatterjee @pranam.bsky.social and his first AI-generated baby #CecamLLMLugano

Traveling to "Generative AI and large language models for protein modeling across sequence-structure-function scales : From predicting protein dynamics to programmable biology and drug design" in Lugano #CecamAILugano @cecamevents.bsky.social

Max Bonomi @bonomimax.bsky.social on IDP modeling by AI @cecamevents.bsky.social #CecamLLMLugano

Prof. Michele Vendruscolo Dr. Zsuzsanna Dosztányi ML4NGP Connect series, organized as part of the ongoing activities of the ELIXIR 3D-BioInfo Community and in collaboration with ISCB and 3DSIG. 📢 Date & Time: 30 September 2025 | 17:00-18:00 CEST Online elixir-europe.org/events/unstr...

Happy birthday ČSBMB #CSBMB2025

Hana Cahová ( @iocbprague.bsky.social ) awarded a medal by CSBMB #CSBMB2025

Kickoff of XXVIII-th congress of the Czech Society for Biochemistry and Molecular Biology ( @febspress.bsky.social member )

Instruct Director Harald Schwalbe will be in Denmark for the SBiNLab’s 25th anniversary! www1.bio.ku.dk/english/rese... @schwalbe-lab.bsky.social Researchers in Denmark can receive access to Instruct technologies and instrumentation here - instruct-eric.org/submit-propo...

Many thanks to @pluskal-lab.org @iocbprague.bsky.social @elixircz.bsky.social for two days of excellent talks at #PragueBioML !

And now something completely different - nanopores! by @scimartin.bsky.social @ethz.ch #PragueBioML @elixircz.bsky.social

Erik Andris @iocbprague.bsky.social on graph NNs #PragueBioML @elixircz.bsky.social

"Second talk" by Anton Bushuiev ( @iocbprague.bsky.social @pluskal-lab.org @josef-sivic.bsky.social ) on protein language models #PragueBioML @elixircz.bsky.social

Intrinsically disordered proteins by @tothpetroczylab.bsky.social #PragueBioML @elixircz.bsky.social

In 2024, IT4Innovations supported thousands of users and hundreds of research projects. Behind every achievement stand people – our colleagues, partners, and supporters – thank you for making it possible. 🇬🇧 www.it4i.cz/cs/file/e5d7... #eINFRAcz

Petr Kouba on protein flexibility #PragueBioML @elixircz.bsky.social

Joan Planas-Iglesias on protein aggregation #PragueBioML @elixircz.bsky.social

Stanislav Mazurenko on evolution and protein design #PragueBioML @elixircz.bsky.social

Aleksej Zelezniak on #AI driven protein engineering #PragueBioML @elixircz.bsky.social

Protein-protein interactions studied by @cyrilmalbranke.bsky.social #PragueBioML @elixircz.bsky.social

Adrian Dobbelstein on DrugFlow #PragueBioML @elixircz.bsky.social

Michael Backenköhler on #drugdesign #PragueBioML @elixircz.bsky.social

Programable protein therapeutics by @pranam.bsky.social #PragueBioML @elixircz.bsky.social

Mrunali Manjrekar @mit.edu on #AI and #MSMS #PragueBioML @elixircz.bsky.social

Roman Bushuiev ( @pluskal-lab.org @iocbprague.bsky.social @josef-sivic.bsky.social ) on #ML and #MS #PragueBioML @elixircz.bsky.social

Bindcraft presented by @martinpacesa.bsky.social #PragueBioML @elixircz.bsky.social

Elizabeth Mahood @iocbprague.bsky.social @mit.edu on CYP #PragueBioML @elixircz.bsky.social

David Harding-Larsen on PRISM enzyme design #PragueBioML @elixircz.bsky.social

Conditional enzyme design by @jsunn-y.bsky.social ( @caltech.edu @francesarnold.bsky.social ) #PragueBioML @elixircz.bsky.social

Matouš Soldát and Hamsini Ramanathan on terpene synthase design @iocbprague.bsky.social #PragueBioML @elixircz.bsky.social

Raman Samusevich @iocbprague.bsky.social on 👃 terpenoids #PragueBioML @elixircz.bsky.social

We continue with enzyme design by talk of @ncorley.bsky.social #PragueBioML @elixircz.bsky.social

Designing new enzymes by #RFdiffusion2 by @jyim.bsky.social #PragueBioML @elixircz.bsky.social

On experiment and AI in enzyme design by @simonmathis.bsky.social #PragueBioML @elixircz.bsky.social

On new enzymatic activities by @arianemora.bsky.social (@francesarnold.bsky.social lab) #PragueBioML @elixircz.bsky.social

On CLIPZyme screening by @pgmikhael.bsky.social @mit.edu #PragueBioML @elixircz.bsky.social

500 million years of loading slides by @countablyfinite.bsky.social @evolutionaryscale.bsky.social #PragueBioML @elixircz.bsky.social

We're sponsoring the use of ESM3 and EMSC to help researchers engineer improved PETase enzymes in the @AlignBio 2025 Protein Engineering Tournament. Get started using ESMC to predict protein function and ESM3 to generate new enzymes here: github.com/evolutionary...

On #machinelearning and #quantumchemistry by @jrezac.bsky.social @iocbprague.bsky.social #PragueBioML @elixircz.bsky.social

BoltzGen #Boltz by @hannes-stark.bsky.social @mit.edu #PragueBioML @elixircz.bsky.social

Carlos G. Acevedo-Rocha on ProteusAI and Denmark #PragueBioML @elixircz.bsky.social

On #Boltz and #drugdesign by @gcorso.bsky.social #PragueBioML @elixircz.bsky.social

Jeremy Wohlwend on #Bolz #PragueBioML @elixircz.bsky.social

A proud sponsor of #PragueBioML is @elixircz.bsky.social @elixir-europe.org

Butkhard Rost @tum.de on AI + code of life #PragueBioML @elixircz.bsky.social

Pavlina Rezacova (vice director of @iocbprague.bsky.social ) kickes off #PragueBioML