🏆 We're thrilled to award this quarter's Editors' Choice Award to: Single-cell analysis of oxidative phosphorylation protein expression in pancreatic islets in type 2 diabetes. By Alana Mullins et al. doi.org/10.1530/JOE-25-0253 Thanks to the authors for your outstanding contribution 👏

Sexual dimorphism shapes thyroid biology. A new review by Caroline C Faria et al. highlights how genetic, epigenetic and hormonal differences influence the entire thyroid axis, from central regulation to hormone metabolism. Explore the article: doi.org/10.1530/JOE-25-0346

Can combined aerobic and resistance exercise improve sarcopenia in older patients with type 2 diabetes mellitus? A new randomised controlled trial by Yuxia Ma et al. reports encouraging improvements following intervention... Read the paper to learn more: doi.org/10.1530/JOE-25-0275

💪New research by Thamires Siqueira de Oliveira et al. demonstrates that low‑dose thyroxine (T4) replacement does not improve muscle regeneration post-injury in elderly mice. Instead, T4 replacement therapy seemed to induce atrophy & tissue remodeling. doi.org/10.1530/JOE-25-0203

New research by C. Yan et al. compared effects of BIBO3304 on diet-induced obesity & glucose intolerance at room temp. (21–22°C) & thermoneutrality (TN, 30°C). Findings support the temperature-dependent efficacy of metabolic drugs. Explore the results: doi.org/10.1530/JOE-25-0233

🐾 Does your research explore multifactorial endocrine disorders with domesticated animals as models? We're dedicating a Special Collection to Comparative Endocrinology. Collection Editors, Dr Eleanor Raffan & Dr Ruth Morgan, welcome submissions of original research & review articles. bit.ly/3KlpdVZ

A new review by Rakesh Meher et al. explores the pathophysiological links between diabetes & cognitive decline. By integrating molecular, genetic and clinical insights, the review highlights how these insights can guide development of personalised dementia therapies. 🔗 doi.org/10.1530/JOE-25-0016

🔬 New study by Alana Mullins et al. introduces IsletAnalytics, semi-automated workflow for segmentation of immunofluorescent-stained human pancreatic islets, revealing altered islet architecture & OXPHOS proteins in T2D β‑cells. Open-access article: doi.org/10.1530/JOE-25-0253

🪩As we approach the end of 2025, we’re launching the Journal of Endocrinology Best Paper Award. Join us to celebrate the year’s most outstanding contributions to the field of endocrinology - winners will be announced in early 2026. 🎆 Learn more: joe.bioscientifica.com/page/award/best-paper-award

New research by M. Mashayekhi (@vanderbilt.edu) et al. explores how the GLP-1R rs6923761 (Gly168Ser) variant modulates response to liraglutide in obesity and pre-diabetes. 🔗Subscribers to Journal of Endocrinology can read the article: doi.org/10.1530/JOE-25-0174

☣️ Cadmium, an endocrine disruptor, is a known reproductive toxin. New research by Yorgui Santiago-Andres et al. reveals the role of cadmium in testicular dysfunction via direct testicular damage & disrupted gonadotroph calcium signalling & hormone secretion. 🔓 doi.org/10.1530/JOE-25-0161

We recognise impactful figures published in Journal of Endocrinology through our Editors' Choice Figure Award. Q3 winner: Figure 2F in 'Obesity duration is linked to bariatric surgery outcomes via adipose tissue response' By Julia Sánchez-Ceinos et al. doi.org/10.1530/JOE-25-0013

🏆 We're thrilled to award this quarter's Editors' Choice Award to: The glucocorticoid receptor is affected by its target ZBTB16 in a dissociated manner (doi.org/10.1530/JOE-...) By Sekar Galuh et al. Thank you to the authors for your contribution!

Intrauterine exposure to triclosan, used in personal care products, may increase susceptibility to thyroid hypofunction in adulthood, highlighting its potential role as a developmental thyroid disruptor. Subscribers to Journal of Endocrinology can read the full article: doi.org/10.1530/JOE-25-0069

As part of our Exploring Osteoporosis and Sarcopenia Special Collection, a new review by Qinzuo Dong et al. examines the pathophysiological mechanisms underpinning osteosarcopenia, providing insights that could shape precision targeting. 🔗Subscribers can read the review: doi.org/10.1530/JOE-25-0234

What role do adipokines play in testicular development? Research by Preehi Riba et al. investigates vaspin & GRP78 expression in postnatal mouse testes & the impact on germ cell proliferation & cell death. Subscribers to Journal of Endocrinology can read the article: doi.org/10.1530/JOE-25-0208

Comparative Endocrinology: Insights from Domesticated Animals🐄 This special collection is open to original research and review submissions that advance our understanding of endocrine disorders through the study of domesticated animal models. 📩Submit your proposal to [email protected]🐎

Research by Dora A Mendez (@ucmerced.bsky.social) et al. suggests that thyroid hormones may enhance antioxidant defenses & protective pathways, pointing towards a cardioprotective role in metabolic syndrome. Subscribers to Journal of Endocrinology can read the article: doi.org/10.1530/JOE-25-0164

🦴New research by Jing Chen et al. explores miR-127-3p in osteoporosis, investigating its regulatory role in human bone mesenchymal stem cells. The study reveals insights into miR-127-3p as a diagnostic biomarker & predictor of osteoporosis. 🔗Full article #OpenAccess: doi.org/10.1530/JOE-25-0032

Tributyltin (TBT) is known for its endocrine-disrupting properties & now recent research by Rosiane Aparecida Miranda et al. reveals that maternal TBT exposure may increase susceptibility to conditions like PCOS in female offspring. 📖 Subscribers can read the article: doi.org/10.1530/JOE-24-0357

Does obesity duration affect bariatric surgery outcomes? Julia Sánchez-Ceinos (@imibic.bsky.social) et al. link weight loss & metabolic improvements to proteomic changes in subcutaneous adipose tissue, highlighting obesity duration as a factor in individual response. 🔗 doi.org/10.1530/JOE-25-0013

🌾 How do pesticides impact reproductive health? A new review by Mariana de Souza Pomacena et al. explores how endocrine-disrupting pesticides may alter reproductive function in both sexes. 🔬 Subscribers can read the review in Journal of Endocrinology: doi.org/10.1530/JOE-...

🧬 Cortisol-induced ZBTB16 may restore baseline cellular state after inflammation & enhance glucocorticoid receptor anti-inflammatory effects. This could guide drug development that reduces side effects while retaining glucocorticoid benefits. 🔗Read the research #OA: doi.org/10.1530/JOE-24-0283

🔗Juliana Woyames et al. explores the link between gestational fish oil supplementation and sex- & muscle-specific alterations in myokine expression in weanling offspring exposed to a maternal high fat diet. Subscribers to Journal of Endocrinology can access the article 👉 doi.org/10.1530/JOE-25-0033

New research by Paula Urones et al. investigate the changes in circulating GDF15 levels in #Obesity and after bariatric surgery. Their research provides important insight into the relevance of GDF15 as a biomarker for clinical outcomes. Check out the article #OpenAccess: doi.org/10.1530/JOE-25-0010

Have you read the summer issue of The #Endocrinologist yet? 📰 Here are our editorial board’s picks of the ‘hot’ papers from the Society's journals and beyond. @joendocrinology.bsky.social @endocancer.bsky.social @natmetabolism.nature.com Dive into the latest hot topics here 👉 bit.ly/3TTIn6f

🏆 Editors’ Choice Figure Award We're thrilled to award this quarter's Editors' Choice Figure to: Glucose and energy metabolism are impaired in mice deficient for orexins By Mélodie Devère et al. 📖 Read the article: doi.org/10.1530/JOE-24-0329 Thank you to the authors for your contribution! 🎉

🏆 This quarter the Journal of Endocrinology Editors' Choice Award goes to: 📌 Maternal sucrose consumption alters steroid levels in the mother, placenta and fetus By Désirée R Seib, Minseon M Jung, and Kiran K Soma Congratulations to the authors! 🎉 📖 Read the full article: doi.org/10.1530/JOE-...

Excited to share our new review article published in @joendocrinology.bsky.social From cholesterol to glucose: uncovering how statins induce β-cell dysfunction to promote type 2 diabetes doi.org/10.1530/JOE-...

We are delighted to have achieved an increased Journal Impact Factor of 3.9 in the latest #JCR2025 report🎉 Thanks to our authors, reviewers and editors for your valued collaboration & contributions. Explore the top-cited articles that contributed 👉 buff.ly/CHqJQDS

Discover how preventive #cardiovascular care could be improved for females in the latest review by Thulani Ashcroft et al. ⭐️Published in the Sex Effects in Endocrine Health and Disease special collection: joe.bioscientifica.com/page/sex-effects Read the full article👉 doi.org/10.1530/JOE-25-0084

🧬New research in gestational #diabetes: Alan C Maloney et al. investigate molecular mechanisms in adipose tissue that may contribute to GDM pathology. 🔗 Subscribers to Journal of Endocrinology can read the full article here: doi.org/10.1530/JOE-...

New research by Napatsorn Imerb et al. explores how lifestyle interventions like #exercise and #CaloricRestriction impact #BoneHealth in obesity-induced bone loss. 🔗 Subscribers to Journal of Endocrinology can read the full article here: doi.org/10.1530/JOE-25-0023

📢 FINAL CALL FOR PAPERS Contribute to our special collection: Exploring Osteoporosis and Sarcopenia. We welcome original research and reviews on bone-muscle cross-talk, metabolic factors, therapeutic targets and translational aspects of osteosarcopenia. 📩[email protected]

Check out this latest study by Jianhong Zhang et al. exploring how cold aerobic exercise may influence #fibrosis in NAFLD via the UBAP2L-regulated TGF-β/SMAD2 pathway. Subscribers to Journal of Endocrinology can access the full article here: doi.org/10.1530/JOE-24-0351

Read the latest article in Journal of Endocrinology's #Incretins Special Collection: The effects of GIP, GLP-1 and GLP-2 on markers of bone turnover: a review of the gut–bone axis By Miriam Longo et al. 👉 doi.org/10.1530/JOE-...

📢 Call for Papers: Sex Effects in Endocrine Health and Disease Special Collection. Showcasing the importance of studying both sexes in translational #endocrinology. Submit your article proposal and help make an impact in this important field ➡️ joe.bioscientifica.com/page/sex-eff...

Research by Jing Zhu et al. concludes the #TEDML prediction model is accurate and reliable, and the identification of CSF3R as a key biomarker and its correlation with drug sensitivity offers new insights into targeted therapy for #thyroid eye disease 👉 buff.ly/kkrwSbD

Check out @socendocrinology.bsky.social's interview with Journal of Endocrinology's co-Editor-in-Chief Associate Professor @gabysxavier.bsky.social! 👉 www.endocrinology.org/endocrinolog...

Jinhuang Xu et al. investigate alterations in the expression of LINC01094 in patients with osteoporotic fractures, evaluate its potential role as a diagnostic biomarker, and explore its effects on osteoblast differentiation. Read it here 👉 buff.ly/VZjErfx

This quarter the Journal of Endocrinology Editors' Choice Award goes to: 📍'Identification of a vimentin-expressing α-cell phenotype in CF and normal pancreas' by Nicole Kattner @newcastleuni.bsky.social et al. Read it here ➡️ doi.org/10.1530/JOE-... Congratulations to the research team 👏

Read these findings by Mélodie Devère et al. supporting the idea that dysfunction of the #orexin system may promote #obesity and #diabetes, and could represent an interesting therapeutic target in the context of ‘diabesity’ 👉 doi.org/10.1530/JOE-...

📍 Reappraising the relationship between hyperinsulinemia and #insulin resistance in #PCOS By Emma J Houston and Nicole M Templeman Read it here 👉 buff.ly/19QY9GF

Submit your paper to the Endocrine Excellence: Discovery Science at #SfEBES2025 Special Collection, and put your research in the spotlight! 👋 Visit the @Bioscientifica stand for more information or 📨 [email protected]. Learn more 👉 buff.ly/41BYiLq

🆕 Check out this recently published paper, 'Steroidogenic Acute Regulatory Protein in Fish' by Jannet Kocerha and Nancy D. Denslow. It's part of our special collection marking 30 years since the #StAR protein was identified and characterized. ✨ ➡️https://doi.org/10.1530/JOE-24-0232

Even more concerning, the bone loss was seen at sites distant from the inflammation. #BoneLoss #Inflammation #Research #AcademicSky

New research on how leptin, an immune-modulating adipokine, might contribute to orthopedic implant failure. The study in ob/ob mice suggests leptin increases inflammation & osteolysis caused by polyethylene particles. #Orthopedics #BoneHealth #Leptin #Nutrition #Biostatistics #AcademicSky

It was a pleasure for our team to be able to contribute to this manuscript on Vimentin+ alpha cells in CF 👇🏻 joe.bioscientifica.com/view/journal...

Read the latest article in Journal of Endocrinology's #StAR Anniversary Collection: 'Thirty years of StAR gazing. Expanding the universe of the steroidogenic acute regulatory protein' by Walter L Miller 👉 https://buff.ly/3QjMyqe

Recent research by Dawood Khan et al. investigated the potential therapeutic role of extrinsic modulators of NPY2R and GLP-1R in estrous cycling, changes in circulating reproductive hormones and their concurrent effects on ovarian and adrenal morphology. Read it here👉 https://buff.ly/3Q7pScL