excited to share our latest work now online @natmetabolism.nature.com, led by @kyle-flickinger.bsky.social, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6

huge congrats to first author @kyle-flickinger.bsky.social, who drove this study as the major component of his PhD thesis & in the process became our resident expert in folate/1C metabolism! also grateful for contributions from @carlosmf.bsky.social @thebiokimist.bsky.social, Gavin…1/n

excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!

Me cold-emailing potential postdoc advisors: