UCSF Peng Lab
@ucsfpenglab.bsky.social
📤 17
📥 53
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Laboratory exploring the fibroblast's role in everything
NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells: Immunity
www.cell.com/immunity/ful...
Excited to present Nancy's postoctoral work
@ucsfaging.bsky.social
@immunox.bsky.social
defining the role of aging fibroblasts in driving inflammaging.
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NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells
Aging is accompanied by significant changes to the immune system. Allen et al. demonstrate that age-related NF-κB activation in fibroblasts remodels the lung resident immune system and promotes the em...
https://www.cell.com/immunity/fulltext/S1074-7613%2826%2900086-5
6 days ago
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Sharing JinYoung's latest work
@ucsfaging.bsky.social
@ucsfstemcell.bsky.social
in collaboration with
@lindsaylafave.bsky.social
on how senescent fibroblasts program tumor plasticity and metabolism. JY is starting her own lab at Inha University.
www.sciencedirect.com/science/arti...
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Senolytic-sensitive p16Ink4a+ fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
Senescence has been demonstrated to either inhibit or promote tumorigenesis. Resolving this paradox requires spatial mapping and functional characteri…
https://www.sciencedirect.com/science/article/pii/S193459092500373X?dgcid=author
5 months ago
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