The LFS UK 2025 conference took place last September, updating on studies from across the country, including MILI. Visit LFS UK 2025 to see the various presentations and update on the MILI trial tinyurl.com/d2dfm36x #TP53 #LiFraumeniSyndrome #LFS @oncology.ox.ac.uk @oxfordcancer.bsky.social

Next up in the Meet The MILI Team series is Beckie Kaemba. Beckie is a genetic counsellor and is part of the MILI team at Leicester Royal Infirmary. #LFS #LiFraumeni @oncology.ox.ac.uk @oxfordcancer.bsky.social George Pantziarka TP53 Trust & Leicester University Hospitals

To learn more about the MILI trial visit mili.octru.ox.ac.uk @OUHospitals.bsky.social @GSTTnhs.bsky.social @cuh.nhs.uk @nottmhospital.bsky.social @NHSGrampian.bsky.social @UHSFT.bsky.social @nhslothian.bsky.social @oxfordcancer.bsky.social @oncology.ox.ac.uk #TP53 #LiFraumeniSyndrome #LFS

@OUHospitals.bsky.social @GSTTnhs.bsky.social @cuh.nhs.uk l @nottmhospital.bsky.social @NHSGrampian.bsky.social @UHSFT.bsky.social @nhslothian.bsky.social & Leicester Uni Hospitals #TP53 #LiFraumeniSyndrome #LFS  George Pantziarka TP53 Trust @oxfordcancer.bsky.social @oncology.ox.ac.uk

Next up in the Meet The MILI Team series, is Dr Julian Barwell. Dr Barwell is a consultant clinical geneticist and is part of the MILI team at Leicester Royal Infirmary. #LFS #LiFraumeni #LFS #LiFraumeni #GeorgePantziarkaTP53Trust @oxfordcancer.bsky.social @oncology.ox.ac.uk

Congratulations to Kendra Perez-Smith, Translational Support Unit Manager, who has received an Outstanding Contribution to Sustainability Award for her innovation & leadership in establishing Lab QuTe: a department-wide network designed to reduce the environmental impact of clinical trials.

Next up in the Meet The MILI Team series, is Sahar Elkady. Sahar is a clinical research practitioner and is part of the MILI team at Nottingham City Hospital. #LFS #LiFraumeni #GPTP53Trust @oncology.ox.ac.uk @oxfordcancer.bsky.social @nottmhospitals.bsky.social

Congratulations to the team at Liverpool for recruiting 203 participants to SCOOT! @lhchft.bsky.social @chestconsultant.bsky.social @oncology.ox.ac.uk #lungcancer #personalisedtherapy and #earlydiagnosis

A MILI Milestone: 50 participants randomised onto the trial! Thank you to all our recruiting sites for support of the trial: @ouhospitals.bsky.social @gstt-nhs.bsky.social @cuh.nhs.uk @nottmhospitals.bsky.social @nhsgrampian.bsky.social @uhsft.bsky.social & Uni Hospitals Leicester #TP53 #LFS

Congratulations to the team at Brighton and Sussex for recruiting 61 participants to SCOOT. @uhsussex.bsky.social @chestconsultant.bsky.social @oncology.ox.ac.uk #lungcancer #personalisedtherapy and #earlydiagnosis

Next up in the Meet The MILI Team series, is Hannah Holdsworth. Hannah is a research nurse and is part of the MILI team at Leicester Royal Infirmary. #LFS #LiFraumeni #georgepantziarkatrust @oncology.ox.ac.uk @oxfordcancer.bsky.social @leicestersresearch.bsky.social

Congratulations to the team at @ouhospitals.bsky.social for recruiting their first participant to SCOOT. Find out more about SCOOT here: www.oncology.ox.ac.uk/clinical-tri... #lungcancer #earlydiagnosis #earlydetection #GMLungHealthCheck @oxfordcancer.bsky.social @chestconsultant.bsky.social

Oxford Professor Sarah Blagden, @oncology.ox.ac.uk appears in the first episode of Cancer Detectives: Finding the Cures on @Channel4 tonight! 📺 Watch at 9pm, Thurs 20 Nov, or stream on Channel 4. Brought to you by @CR_UK. #CancerDetectives #CancerPrevention www.channel4.com/programmes/c...

We’re thrilled to partner with Channel 4 on ‘Cancer Detectives: Finding the Cures’ - a new series which is shining a light on three trailblazing scientists taking on cancer, and explores how their work is changing patients’ lives right now. 👇 1/2

Next up in the Meet The MILI Team series, is Resifina Seyara. Resifina is a research nurse and is part of the MILI team at Aberdeen Clinical Genetics. #LFS #LiFraumeni #georgepantziarkatrust @oncology.ox.ac.uk @oxfordcancer.bsky.social @nhsgrampian.bsky.social

World’s first lung cancer prevention vaccine gets £2 million for clinical trial People at high risk of lung cancer will soon be able to receive the experimental vaccine, 'LungVax', designed to prevent the disease, in a world-first clinical trial. @medsci.ox.ac.uk @oxfordcancer.bsky.social

Big news! 🚨 People at high risk of lung cancer will soon be able to receive the first ever experimental vaccine designed to prevent the disease, in a world-first clinical trial. Read more: cruk.ink/4r4KXG2 @ox.ac.uk @ucl.ac.uk

OCTO Director Prof Sarah Blagden features in a new Channel 4 doc "The Cancer Detectives: Finding the Cures" an observational documentary series exploring pioneering research that could transform the future of cancer detection, treatment and prevention: www.oncology.ox.ac.uk/news/profess...

It’s important to know the signs of lung cancer even if you’re not a smoker. Watch this short video to find out more: youtu.be/sKuM8k3G87k?... #earlydetection #GMLungHealthCheck @oxfordcancer.bsky.social @chestconsultant.bsky.social

Next up in the Meet The MILI Team series, is Dr Schaida Schirwani. Dr Schirwani is a genetics consultant and is part of the MILI team at University Hospital Southampton. #LFS #LiFraumeni @uhsft.bsky.social @oncology.ox.ac.uk @oxfordcancer.bsky.social tp53.co.uk/lfs-tp53/

Sruthi Shakthivel is a technician in the Translational Support Unit (TSU), a dedicated unit within @octooxford.bsky.social that focuses on the operational & scientific side of biological sample management in clinical trials. Sruthi shares insights on the mission of the TSU & what her role involves:

Introducing our Meet The MILI Team series! Each week will feature a different team member. We are starting off with the brains behind the trial, our very own Clinical Investigator, Prof Sarah Blagden: #LFS #LiFraumeni @oncology.ox.ac.uk @oxfordcancer.bsky.social tp53.co.uk/lfs-tp53/

Congratulations to the team at South Tyneside and Sunderland for recruiting 60 participants to SCOOT. @stsftrust.bsky.social @chestconsultant.bsky.social @oncology.ox.ac.uk #lungcancer #personalisedtherapy and #earlydiagnosis

The MILI trial aims to determine whether a medication called metformin will reduce the chance of developing cancer in people with LFS. To learn more about the MILI trial and LFS, visit mili.octru.ox.ac.uk and The George Pantziarka TP53 Trust: tp53.co.uk/lfs-tp53/

The MILI site team based in Leicester Royal Infirmary share why working with clinical trials is important to them. Find out more about MILI here: mili.octru.ox.ac.uk #LFS #TP53 #LiFraumeniSyndrome #LeicesterRoyalInfirmary

The MILI site team based at Aberdeen Royal Infirmary share what this study means to them. Find out more about MILI here: mili.octru.ox.ac.uk #LFS #TP53 #LiFraumeniSyndrome @NHSGrampian

‘The GPTP53 trust have published some more information about the MILI trial. Visit their website to find out more: www.tp53.org.uk/mili-trial-f... #LFS #LiFraumeniSyndrome @oncology.ox.ac.uk @oxfordcancer.bsky.social

The MILI site team based in Leicester Royal Infirmary speak on what this study means to them. Find out more about MILI here: mili.octru.ox.ac.uk #LFS #TP53 #LiFraumeniSyndrome

Members of the MILI Trial team are attending the 2025 CRUK Cancer Prevention Research Conference this week. @cancerresearchuk.org @oxfordcancer.bsky.social #CRUK #LFS

#InternationalNursesDay #InternationalNursesDay2025

To all the research nurses working on the SCOOT trial. Thank you for all that you do! #InternationalNursesDay #InternationalNursesDay2025

To all the research nurses working on the MILI trial! @ouhospitals.bsky.social @gstt-nhs.bsky.social @cuh.nhs.uk @nhsgrampian.bsky.social @uhsft.bsky.social @leicestersresearch.bsky.social @nottmhospitals.bsky.social #InternationalNursesDay #LFS #TP53

To all the research nurses working on the TebeMRD trial. #InternationalNursesDay #InternationalNursesDay2025

On #InternationalNursesDay...

A MILI Milestone: 30 participants randomised onto the trial! #TP53 #LiFraumeniSyndrome #LFS @oncology.ox.ac.uk @oxfordcancer.bsky.social The George Pantziarka TP53 Trust

What is LFS? A person with LFS carries a pathogenetic variant in their TP53 gene associated with an increased risk of cancer. To find out more about LFS and current research, including the MILI clinical trial: MILI tinyurl.com/nu3w4ba3 TP53 Trust tinyurl.com/yufxf4um #LFS @oxfordcancer.bsky.social

The MILI trial is pleased to announce that our 7th site, University Hospitals of Leicester NHS Trust, is now open to recruitment! #TP53 #LiFraumeniSyndrome #LFS @leicestersresearch.bsky.social @oxfordcancer.bsky.social @oncology.ox.ac.uk

The MILI trial is pleased to announce that our 6th site, University Hospital Southampton NHS Foundation Trust, is now open to recruitment! @uhsft.bsky.social @oxfordcancer.bsky.social @oncology.ox.ac.uk #TP53 #LiFraumeniSyndrome #LFS

MILI Participants, we want to hear from you! #TP53 #LiFraumeniSyndrome #LFS #OxfordCancer #rarediseases @oxfordcancer.bsky.social @oncology.ox.ac.uk @ouhospitals.bsky.social @cuhnhs.bsky.social @nottmhospitals.bsky.social @nhsgrampian.bsky.social @gstt-nhs.bsky.social

The full title of the MILI trial is "Metformin in Li Fraumeni Syndrome Trial: A phase II randomised open-label cancer prevention trial of metformin in adults with Li Fraumeni Syndrome". But what does "randomised" mean, and why is it done... (1/2) @oxfordcancer.bsky.social @oncology.ox.ac.uk

#WorldCancerDay #UnitedByUnique @oncology.ox.ac.uk @oxfordcancer.bsky.social @octructu.bsky.social

#WorldCancerDay #UnitedByUnique TebeMRD Trial website: tebemrd.octru.ox.ac.uk

#WorldCancerDay #UnitedByUnique @oncology.ox.ac.uk @oxfordcancer.bsky.social

SCOOT is a study aiming to use blood biomarkers to help diagnose lung cancer more accurately and quickly than we can now. Find out more about SCOOT here: tinyurl.com/SCOOT-OCTO #worldcancerday #unitedbyunique #earlydetection @oncology.ox.ac.uk @oxfordcancer.bsky.social @octructu.bsky.social

#WorldCancerDay #UnitedByUnique @oncology.ox.ac.uk @oxfordcancer.bsky.social

The MILI trial will help to understand: · How cancers form in Li Fraumeni Syndrome (LFS) · How metformin affects this · The impact of having LFS on quality of life #WorldCancerDay #UnitedByUnique #LFS @oncology.ox.ac.uk @oxfordcancer.bsky.social 1/2

In the UK, nearly 1 in 2 people will get cancer in their lifetime. It's World Cancer Day today – a global day to raise awareness and take action against cancer 🌍 Whatever your cancer experience, share this post and help us get the word out. #WorldCancerDay #WCD2025

On #WorldCancerDay, we're advancing early detection by studying biomarkers to identify high-risk individuals. We're also exploring immunotherapies to stop cancer early—potentially changing its course https://buff.ly/40ZXoIm #CancerResearch #EarlyDetection

Research is stronger when shaped by the voices of those affected by cancer. 🌱 Patient & Public Involvement empowers individuals to contribute to research, ensuring that our researchers, and their studies, benefit from the perspectives of people affected by cancer Find out more: buff.ly/40Mmd90

#WorldCancerDay is putting a spotlight on the unique needs of everyone impacted by cancer. People-centred care is crucial for equity, quality & efficiency, and means putting the comprehensive needs of people and communities, not only diseases, at the centre of health systems. #UnitedByUnique