On NEJM AI Grand Rounds, Dr. Karandeep Singh shares how childhood coding projects grew into a career at the intersection of #AI and medicine. Hear more from Dr. Singh: nejm.ai/ep34 #MedSky #MLSky

Editorial by Nicoline B.M. Voet, MD, PhD: AI-Enabled Video Biomechanics: A New Frontier for Clinical Care and Trial Readiness in Neuromuscular Disease nejm.ai/4mE0BFR #AI #MedSky #Neurology

A new review summarizes the current state of the art in network medicine and #AI as a combined approach to the analysis of complex biomedical systems governing disease. Use of this unique and highly effective strategy provides a path to precision medicine. nejm.ai/4mtEamy #MedSky #MLSky

Join us for our next free virtual event exploring the complex web of priorities behind AI models in health care. 📅 October 9 🕛 12 PM–1:30 PM ET 📍 Virtual Learn more and save your spot: nejm.ai/41ZDYDl

A new editorial contextualizes the article by Ruth et al. within the broader emerging ecosystem of movement as a biomarker and describes how hurdles to real-world use are now transitioning from technological to operational. Full editorial: nejm.ai/4mAblVt

New AI Grand Rounds! Dr. Karandeep Singh explains how early experiments with code led him to biomedical informatics, why gaps between paper performance and clinical reality must be confronted, and how governance committees weigh ethics and safety. Listen to the full episode: nejm.ai/ep34

A new study presents a comprehensive framework and protocols for safely integrating ambient #AI into routine clinical care, focusing on EHR integration, governance, and real-time monitoring of AI-driven clinical note documentation. Learn more: nejm.ai/420zOLm #MedSky #MLSky

A new study demonstrates that smartphone video–based biomechanical analysis can accurately replicate traditional timed function tests while also capturing disease-specific movement patterns that timed function tests fail to detect. Learn more: nejm.ai/3UKthRc #AI #MedSky #NeuroSky

A new Perspective highlights the significant potential of #AI to advance Diabetes Precision Health and summarizes key challenges and actionable strategies identified by experts to accelerate progress in this emerging field. Learn more: nejm.ai/3HvWVXt #MedSky #EndoSky

Commenting on a study by Ruth et al. on AI-enabled video biomechanical analysis, the authors of a new editorial write that this approach offers a scalable, objective, and sensitive modality for improving both clinical care and the design of neuromuscular disease trials. nejm.ai/4mE0BFR

As AI becomes increasingly embedded in clinical decision making, a key question arises: whose values are represented? The next @ai.nejm.org free virtual event will examine how values shape models, influence care & challenge alignment w/ professional & ethical standards. Sign up: nejm.ai/3JxzJIU

Administrative #AI is just the start. On NEJM AI Grand Rounds, Dr. Jeremy Friese sees the long-term payoff in on-demand quality care. Hear more from Dr. Friese: nejm.ai/ep33 #MedSky #MLSky

#ZakKohane on #AI in #PeerReview: the surge in scientific publication is straining the conventional review system beyond capacity. @ai.nejm.org piloting AI-augmented fast track review: manuscripts w high prior of being good gets assigned to #GPT5 + a human, disposition reviewed by editorial team!

Start with the problem, not the tool. On NEJM AI Grand Rounds, Dr. Jeremy Friese says tech should serve the challenge, not drive it. Listen to the full episode: nejm.ai/ep33 #AI #MedSky #MLSky

As #AI becomes increasingly more involved in clinical decision-making, it is important to understand whose values are being represented. In our next event, experts will discuss the complex web of priorities behind AI models in health care. Sign up: nejm.ai/41ZDYDl

Call for Papers: AI Implementation in Care Delivery NEJM Catalyst Innovations in Care Delivery invites manuscripts to be considered for inclusion in an upcoming special issue on implementation of AI and machine learning in care delivery. Learn more and submit a manuscript: nej.md/476CFpG

#AI won’t replace doctors — it will augment them. On NEJM AI Grand Rounds, Dr. Jeremy Friese sees technology making clinicians even better. Hear more from Dr. Friese: nejm.ai/ep33 #MedSky #MLSky

Perspective by A.K. Malhotra et al.: Energy Considerations for Scaling Artificial Intelligence Adoption in Medicine: First Do No Harm nejm.ai/3Je3myN @armaan-km.bsky.social #AI #MedSky #MLSky

Perspective by Irene Y. Chen, PhD, and Emily Alsentzer, PhD: Redefining Bias Audits for Generative AI in Health Care nejm.ai/4mhOFte @irenetrampoline.bsky.social @emilyalsentzer.bsky.social #AI #MedSky #MLSky

Datasets, Benchmarks, and Protocols by Y. Jiang et al.: MedAgentBench: A Virtual EHR Environment to Benchmark Medical LLM Agents nejm.ai/45AUXwS #AI #MedSky #MLSky

Volume 2, No. 9 of NEJM AI is now available! Here is a preview of the latest content: 𝗘𝗱𝗶𝘁𝗼𝗿𝗶𝗮𝗹𝘀 AI-Enabled Video Biomechanics: A New Frontier for Clinical Care and Trial Readiness in Neuromuscular Disease nejm.ai/4mE0BFR #MedSky #AI #MLSky

New in NEJM Catalyst Innovations in Care Delivery: Type 2 Diabetes Pharmacotherapy De-Escalation Through AI-Enabled Lifestyle Modifications: A Randomized Clinical Trial nej.md/41aafHw #AI #MedSky #MLSky

From rural roots to health care reformer: On NEJM AI Grand Rounds, Dr. Jeremy Friese shares the loss that drives his mission. Listen to the full episode: nejm.ai/ep33 #AI #MedSky #MLSky

🧠 In @nejm.org, Raja-Elie Abdulnour et al. warn: AI in medical training risks deskilling & mis-skilling. They propose DEFT-AI to teach critical thinking & safe human-AI collaboration. Verify, then trust. 📖 doi.org/10.1056/NEJM... #ResearchEthics #MedicalEducation

AI is transforming health care delivery, but its environmental impact remains underexamined. The authors of a new Perspective consider the factors and frameworks that may enable environmentally responsible use of AI in medicine. Learn more: nejm.ai/3Je3myN #AI #MedSky #MLSky

A new Perspective explores the shortcomings of traditional auditing methods for large language models in health care and offers targeted recommendations to enhance bias evaluation in practical, real-world settings. Learn more: nejm.ai/4mhOFte #AI #MedSky #MLSky

MedAgentBench, a comprehensive benchmark designed to evaluate the agentic capabilities of large language models in realistic EHR environments, provides a critical foundation for advancing and integrating LLM agents into clinical workflows. Learn more: nejm.ai/45AUXwS #AI #MedSky #MLSky

In the latest episode of the NEJM AI Grand Rounds podcast, Dr. Jeremy Friese walks through the origins of prior authorization, explains why he believes #AI can close the gap between patients and payers, and argues that real reform means showing your work. Full episode: nejm.ai/ep33

Editorial by Jonathan Witonsky, MD, MAS, and Nirav Bhakta, MD, PhD: AI for Spirometry Interpretation in Primary Care nejm.ai/46WAhS6 #AI #MedSky #MLSky

Original Article by G. Doe et al.: AI-Assisted Spirometry Interpretation in Primary Care: A Randomized Controlled Trial (SPIRO-AID) nejm.ai/46WAhS6 #AI #MedSky #MLSky

A 5000% price hike — with no clinical benefit. On the latest episode of the NEJM AI Grand Rounds podcast, Dr. Andy Beam discusses what his lab found when they studied Makena. Learn more: nejm.ai/ep32 @andrewlbeam.bsky.social #MedSky #AI

#AI and machine learning tools promise greater accuracy and efficiency in both diagnosis and decision-making, as well as access to high-quality care. Yet model development has outpaced critical appraisal, especially in pulmonary function testing. nejm.ai/4o2VoZa #MedSky

In the SPIRO-AID trial, the adjunctive use of #AI spirometry decision support software, which has the potential to help address unmet needs in primary care, significantly improved diagnosis prediction performance. Full trial results: nejm.ai/46WAhS6 #MedSky #MLSky

Perspective by R. Andrew Taylor, MD, MHS: AI Agents, Automaticity, and Value Alignment in Health Care nejm.ai/4lDyK81 #AI #MedSky #MLSky

Muscle memory beats white papers. On the latest episode of the NEJM AI Grand Rounds podcast, Dr. Andy Beam urges physicians to learn what models can — and can’t — do by practicing with them. Listen to the full episode: nejm.ai/ep32 @andrewlbeam.bsky.social #MedSky #AI

Perspective by A.H. Lee et al.: The Student Physician–Patient–AI Relationship nejm.ai/44VgDU8 #AI #MedSky #MedEd

Perspective by J. Weberpals et al.: Opportunities for Causal Machine Learning in Precision Oncology nejm.ai/3GOpfnl #AI #MedSky #ML

Editorial by Arya S. Rao, BA, and Anthony R. Artino, Jr., PhD: AI-Driven OSCE Preparation in Medical Education: Promise, Pitfalls, and Practical Implications nejm.ai/3GyaXat #AI #MedSky #MLSky

Original Article by J. Li et al.: An Electrocardiogram Foundation Model Built on over 10 Million Recordings nejm.ai/3TJHs8q #AI #MedSky #CardioSky

Case Study by Eric Wu, PhD, Kevin Wu, PhD, and James Zou, PhD: Limitations of Learning New and Updated Medical Knowledge with Commercial Fine-Tuning Large Language Models nejm.ai/4nTx1Np @jameszou.bsky.social #AI #MedSky

Editorial by V. L. Murthy, MD, PhD: The Generalist–Specialist Paradox of Medical AI nejm.ai/4nm6054 #AI #MedSky #MLSky

Original Article by J. Li et al.: Expert-Level Detection of Epilepsy Markers in EEG on Short and Long Timescales nejm.ai/4lq1Qr4 #AI #MedSky #NeuroSky

Original Article by E. Lavigne et al.: AI-Standardized Clinical Examination Training on OSCE Performance nejm.ai/3TEiuHO #AI #MedSky #MLSky

On the latest episode of the NEJM AI Grand Rounds podcast, Dr. Andy Beam shares how a missed diagnosis broke his reverent view of doctors — and sparked a career in medical #AI. Full episode: nejm.ai/ep32 @andrewlbeam.bsky.social #MedSky

Original Article by T. Adnan et al.: AI-Enabled Parkinson’s Disease Screening Using Smile Videos nejm.ai/4nk6PeD #AI #MedSky #NeuroSky

Volume 2, No. 8 of NEJM AI is now available! Here are the latest articles:   Editorial: AI-Driven OSCE Preparation in Medical Education: Promise, Pitfalls, and Practical Implications nejm.ai/3GyaXat #MedSky #AI #MLSky

In a new Perspective, R. Andrew Taylor, MD, MHS, frames AI agents as a transformative advancement in health care AI, offering unprecedented capabilities but raising complex ethical challenges. Learn more: nejm.ai/4lDyK81 #AI #MedSky #MLSky

ECGFounder, a general-purpose foundation model for cardiovascular disease detection, demonstrates strong generalization and outperforms baseline models on diverse tasks, enabling scalable, cloud-integrated cardiac monitoring. Learn more: nejm.ai/3TJHs8q #AI #MedSky #CardioSky

Six frontier large language models evaluated on incorporating newly updated medical knowledge through commercial fine-tuning application programming interfaces struggled to generalize updated information, despite modest gains. Learn more: nejm.ai/4nTx1Np @jameszou.bsky.social

In an editorial, V. L. Murthy, MD, PhD, writes that we may be entering an era of specialist–generalist medical #AI paradox, wherein AI more rapidly advances in performing tasks that humans require specialization to perform than in general medical tasks. nejm.ai/4nm6054 #MedSky #MLSky