Interested in measuring RNAPII elongation rates? We developed DRB/TTchem-seq2 to directly measure rates across 3,000+ genes 🧬 genome.cshlp.org/content/earl... This fantastic work led by Haiyue Liu reveals gene and intra-genic variation, links to histone marks & elongation factors Details below! 👇

I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms www.nature.com/articles/s41...

🚨We are looking for post-doctoral candidates to apply for a MSCA fellowship. Projects on gene regulation in neural development or neurdegenerative diseases using single-cell omics. Computational & wet-lab candidates are welcomed! #postdoc #MSCA #Barcelona #singlecell.

🚨 We’re recruiting PhD students! 🚨 Join the Stem Cell Biology and Evolution lab at @lsiexeter.bsky.social to study planarians, stem cells & evolution. 2 projects available - 1 week left to apply! Interested and no PhD yet? Apply now. Or help us spread the word! 🙌 www.exeter.ac.uk/research/ins...

Franz Arnold Ake from @idibell.bsky.social presented SCALPEL, a Nextflow-based pipeline to quantify and characterize isoforms at single-cell resolution. Fascinating work that will be applied to study alternative polyadenylation during neural differentiation and neurodegenerative diseases.🧠

Enjoy the #NextflowSummit, @franzake.bsky.social! Excited to see you are spreading the word! summit.nextflow.io/2025/boston/...

It’s so nice to see this work finally out! It developed so much since its early days. The idea of long lived RNA as experience decoys is huge. Still a lot of work to be done but this is a great first step forward. Happy to have been part of it!

Huge effort from @anaconesa.bsky.social at @scb.iec.cat comparing long-read RNA technologies @pacbio.bsky.social @nanoporetech.com and softwares #sqanti3, #bambu, #talon, #isoquant, for isoform discovery, still challenging to disentangle real biology from artefacts

for closing the day at the #XIIJornadesBioinformàticaiGenòmica from @scb.iec.cat we have Akshay presenting a poster about STAU2 function in neurogenesis.

Thrilled to have shared my mayfly research from @isabelalmudi.bsky.social lab at the #XIIJornadadeBioinformàticaiGenòmica in Lleida, organised by @scb.iec.cat. An inspiring day of brilliant talks and meaningful discussions! #EvoDevo #Bioinformatics #scRNAseq

Spreading our work at the XII Jornades de Bioinformàtica i Genòmica de la @scb.iec.cat @tmontsay.bsky.social about our recent discovery rdcu.be/d04Gz of pervasive presence of not completly lysed cells in reference cell atlases @humancellatlas.org compromising quality & model training

and now a talk by Franz Ake presenting SCALPEL, a pipeline for isoform quantification in single-cell data. #XIIJornadesBioinformàticaiGenòmica from @scb.iec.cat . #Nextflow #single-cell

Brilliant presentation by @jamesasharpe.bsky.social at XII Jornades de Bioinformàtica i Genòmica by @scb.iec.cat about mechanistic dynamical models and #Turing patterns to go from genes to phenotypes

first time scr4eam goes public! realistic & isoform-aware simulator of single-cell reads. short talk from @mschilli87.bsky.social at the #XIIJornadesBioinformaàticaiGenòmica #benchmarktools #scrna-seq