Welp, i got halfway through the RPPR and then received notice the MOSAIC program, and thus my MOSAIC R00 has been terminated. Thank you to those who made this program. Thank you to the other #NIHMOSAIC fellows have supported me through my faculty journey and continue to inspire me.

John Mellnik, Jack Scannell: Tripartite models for estimating the value of drug candidates and decision tools https://arxiv.org/abs/2503.22117 https://arxiv.org/pdf/2503.22117 https://arxiv.org/html/2503.22117

The Department of Chemistry and Biochemistry at UC Santa Cruz is looking for a General Chemistry Assistant Teaching Professor - recruit.ucsc.edu/JPF01884 We truly value teaching and mentoring and looking for like minded applicants. Please apply, share, and recommend people who might be interested.

Opinion piece in the @scsentinel.bsky.social by me, @carpenterlab.bsky.social and Carol Greider: Trump is turning off the lights on biomedical research: Why it matters for Santa Cruz www.santacruzsentinel.com/2025/03/20/g...

My most challenging postdoctoral project, where we show that histones but not nucleosomes are polyubiqutinated by the APC/C for a potential proteasomal degradation was just published in @naturecomms.bsky.social 🎉 www.nature.com/articles/s41... Big shout-out to all co-authors!!!

UC Santa Cruz researcher Upasna Shrarma and team uncover four novel genes essential for male fertility in mice, contributing to her broader federally funded research on how a father’s life experiences & environment influence the health of his children.🔬👨‍🍼 #ScienceNews news.ucsc.edu/2025/03/trna...

Really nice infographic of the cost of federally sponsored research. www.cogr.edu/sites/defaul...

JEDI awards provide input on a manuscript, short grant proposal, or job application to scientists facing unfair, systemic barriers to career progression. Next deadline March 10th - please share & apply! lifescienceeditors.org/apply/

After an exciting year of setting up my lab and life in Santa Cruz I am back on bluesky and hope to interact with y'all more. I'm gearing up towards setting up an arrayed CRISPR screen and wonder what are your favorite companies to work with for guide RNAs. Edit Co, IDT, Horizon?

Super useful and eminently readable demystification of writing a successful NIH grant application, written by NIH Program Officers (POs) with LOTS of great guidance:

It's hard to be a new PI and new mom without a daycare (yet). Sending ♥️ to all moms in academia.

Happy International Day of Women and Girls in Science!!!

Exciting news - my lab is hiring a junior scientist! Please apply if you are interested in learning lots of biochemistry and helping me run the lab. recruit.ucsc.edu/JPF01676

Great job opportunity at UNC Chapel Hill for anyone who wants to learn or dive deeper into CryoEM. Josh (core director) is fun to work with and continues to develop new approaches and methods in CryoEM. Therefore this appointment is not just a routine technical work it's actually very creative!

I opened the eggnog season today. A little balm to my heart in these difficult times. Cheers.

Yesterday I received a Postdoctoral Award for Research Excellence 🎉 Having my friends and family in the audience was incredibly moving. What a year ?! 1) I got a dream job, 2) I had a baby and now 3) this award. I'm incredibly grateful for everyone who made it possible 😊

I'd also add that Alphafold doesn't predict interactions of nucleic acids with proteins, which are the basis of so many biological processes.

Nice news and views article covering our recent manuscript on bacterial histones. Thanks for covering this! www.nature.com/articles/s41...

I'm trying to add my profile photo, I save changes, but it turns black when I go back to home view. Any advice?

UNC PARE ceremony is next Friday at 3PM (10/27/23) 🎉 research.unc.edu/2023/10/18/2...