I have seen this story in progress for many years now, so I am thrilled to see Fatema's manuscript on bioarxiv! Such a cool story. Also rumor has it Fatema is on the job market AND just scored a K99 so search committees next year keep your eyes open for that app! www.biorxiv.org/content/10.6...

Engineered OAA lectins as selective and sensitive high mannose glycan targeting tools https://www.biorxiv.org/content/10.64898/2026.03.04.709641v1

I am REALLY excited to share this manuscript from my group now on bioarxiv. Here we used the OAA lectin scaffold to ask can lectins be evolved to have specific interactions for defined glycan structures . www.biorxiv.org/content/10.6...

I need my those bioarxiv manuscript vetters to vet my manuscript asap because i cant wait to share it with yall...

Nuclear Magnetic Resonance Facility Lead (NMR Facility Manager) the Department of Chemistry and Biochemistry, California State University, San Diego, CA careers.sdsu.edu/en-us/job/55... #NMRchat #NMR #NMRjobs 🧲

I feel like now will be a rush to get the rest of the remaining 4 letter PDB codes... In a couple of weeks we will be dropping a preprint (w/ one of the coolest PDB codes btw...) so stay tuned...

it would be great if each journal had a list what each status for their "manuscript status" types mean somewhere.... and the NIH too...

Me: ordering Girl Scout cookies online feels so wrong Also me: oh (grad students kid) has a link to order send it my way…

Really cool work from Eugene’s group. I got to hear about it straight from the source at the protein folding dynamics conference this week!

Some Pielakers past and present and honorary took Gary to an airplane museum today during the GRC! What a thrill!

My postdoc advisor is an advocate for the “post faculty fellow” positions and in theory it sounds like a super cool idea. That being said if anyone is wanting to do one in my lab, Please email me a CV and cover letter.

Successful Christmas in the Guseman household as we experimented with new recipes! Dinner for five !

Really excited to share a manuscript from the group. Here we worked with Julia Staubers group to look at Fe(II) based glycan displays as glycomimetics for high mannose glycans. www.biorxiv.org/content/10.6...

This one is probably the best conference view …

i received my first "hate mail" this week from a retired big name in my field. Essentially he said my recent work was trash and I didnt read/cite one of his papers from the year i graduated high school (shockingly it was irrelevant to the story). Do I respond or nah? *bsky needs polls

I didn’t have an ER trip on my turkey day plans…. Thanks to the folks at ucsd med she’s all patched and we are ready to go host thanksgiving!

Was in downtown San Diego tonight while SfN was going on. I was in line behind a group of students who had UNC on their SfN badges and struck up a convo. They told me they were the last UNC imsd class, because it was cancelled. That shook me. UNC IMSD is the reason I didn’t quit and am still here.

Not every mentor is for every person. I always tell grad students to listen to what folks in the lab say about a mentor, but it’s okay to also see it for yourself in a rotation. It’s about the match - finding the person who can meet your needs (which are unique!).

This was a topic discussed in my group this week. anyone who might have a decent answer for this and or how to show an official transcript when they have not completed a semester yet ... we are all ears on suggestions...

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

I just realized frank the bunny was the original labubu... not sure if it's kind of funny or kinda sad?

April did a cake swap! Which resulted in a post swap cake picnic!

When 6 biochemically oriented PIs go out for cocktails and this is the page of the guest book the check comes out in.

Just a totally normal Halloween lecture I swear…

April and I went to a Wizard of Oz themed party tonight, she went as the beautiful and elegant glinda, and I decided to be the yellow brick road. It was a fan favorite.

This is absolutely heartbreaking, Zara was an absolutely wonderful person and wonderful scientist. She also had a great taste in cocktails bar as we realized we were both regulars at Butterjoint in Pgh during different timeframes. She will be dearly missed.

Whenever Angela talks about our work on y-crystallins/cataracts she prefaces it by showing Monet's work pre and post cataracts.

When you get given a box full of Shigemi tubes 😀 When you realize most of them a varian Shigemis 😭

nows that MoFs have won the Chem Nobel we can get back to real (bio)chemistry prizes!

I know of a lot of high powered magnets in Pittsburgh…. But I didn’t know I could use them to move furniture !!

🐧🐧🐧🌸🌸🌸🐧🐧🐧 Thank you Marc Andre for all the memories!!!! (Picture courtesy of Father in law)

anyone ever have a cytiva column valve confuse upflow and downflow?

NMRSky! Is there any way to indicate multiple peak assignments for a single spin system (I.e., exchange where two peaks for one amide are visible) in a BMRB deposition? @nmr900.bsky.social Thanks!

anyone else seeing insane tarrif charges? 24% more expensive?!?!

Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...

Me: Ugh i shouldn't have agreed to review this manuscript it does not match the abstract and is going to be a lot of work when i should be writing a grant... Also me: oooo invitation to review another manuscript that I know is going to be interesting...✅ *sigh* at least this 2nd one will be easy

How the fuck am I supposed to plan my lab finances if my grants keep getting terminated and reinstated and terminated again? End rant.

Want to attend #bps2026 in San Francisco but need help with funding to get there? BPS offers travel awards for students and scientists at every career level. Deadline to apply is October 3 (and you have to submit your abstract by October 1!)

UCSD is holding a town hall with @repscottpeters.bsky.social this Wednesday to urge him to oppose proposed research funding cuts in the FY2026 budget, set for a vote in September. Please RSVP below and share widely. Everyone is welcome. form.laborbase.org/251675765832...

anyone have bead bath bead suggestions that are affordable? Or any hacks, can I go to wally world and by 500 worth of BB gun ammo (on my p-card) thats made of the same material?

Thrilled to share this manuscript from my lab where we looked at how glycopolymers that compose the glycocalyx influence protein folding and protein-protein interactions via macromolecular crowding. TLDR: The Glycocalyx stabilizes protein folding and PPIs www.biorxiv.org/content/10.1...

Me citing my manuscript about to raise my PhD advisors H-index by at least 2 when this manuscript drops....

These are some of the scientists supported by the mosaic grants in the described amicus brief. Thank you to ASM, FASEB and ASCB in joining ASBMB in supporting us. asm.org/press-releas...

But the orange pumpkin told me that the tariffs wouldn't raise prices and that other countries would be paying for it...

Roy running for senate makes me want to move back to NC to vote for him again.

Through the ups and downs of the job market, to starting my faculty career, to everything going on today. I could not have asked for a greater group of scientists to learn from, grow with, and call friends . Thank you. @asbmb.bsky.social #mosaicforever

When work takes you back east. Sometimes you get lucky and get to visit the family at the lake!

Raise your hand if you have already poisoned your ChatGPT pro to tell you what you want/how ANYTHING applies to your work without asking…. Btw it only took like a week and not that much use…