Alex Guseman
@alexguseman.bsky.social
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📥 337
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Assistant professor at UCSD Chemistry and Biochemistry. Pens fan & bbq enthusiast.
When you get given a box full of Shigemi tubes 😀 When you realize most of them a varian Shigemis 😭
6 days ago
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nows that MoFs have won the Chem Nobel we can get back to real (bio)chemistry prizes!
15 days ago
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I know of a lot of high powered magnets in Pittsburgh…. But I didn’t know I could use them to move furniture !!
add a skeleton here at some point
22 days ago
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🐧🐧🐧🌸🌸🌸🐧🐧🐧 Thank you Marc Andre for all the memories!!!! (Picture courtesy of Father in law)
25 days ago
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anyone ever have a cytiva column valve confuse upflow and downflow?
about 1 month ago
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reposted by
Alex Guseman
Emery Usher, Ph.D. 🏳️🌈🏳️⚧️🧪
about 1 month ago
NMRSky! Is there any way to indicate multiple peak assignments for a single spin system (I.e., exchange where two peaks for one amide are visible) in a BMRB deposition?
@nmr900.bsky.social
Thanks!
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anyone else seeing insane tarrif charges? 24% more expensive?!?!
about 1 month ago
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reposted by
Alex Guseman
Itay Budin
about 1 month ago
Very excited to share new work out today in
@natchembio.nature.com
on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n)
www.nature.com/articles/s41...
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Leaflet-specific phospholipid imaging using genetically encoded proximity sensors - Nature Chemical Biology
An approach combining bioorthogonal chemistry with genetically encoded fluorogen-activating proteins enables subcellular imaging of phospholipids and glycans, as well as the visualization of lipid tra...
https://www.nature.com/articles/s41589-025-02021-z
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Me: Ugh i shouldn't have agreed to review this manuscript it does not match the abstract and is going to be a lot of work when i should be writing a grant... Also me: oooo invitation to review another manuscript that I know is going to be interesting...✅ *sigh* at least this 2nd one will be easy
about 1 month ago
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How the fuck am I supposed to plan my lab finances if my grants keep getting terminated and reinstated and terminated again? End rant.
2 months ago
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reposted by
Alex Guseman
Biophysical Society
2 months ago
Want to attend
#bps2026
in San Francisco but need help with funding to get there? BPS offers travel awards for students and scientists at every career level. Deadline to apply is October 3 (and you have to submit your abstract by October 1!)
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BPS2026 Travel Awards | Biophysical Society
Travel Award FAQs
https://buff.ly/mBex08l
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reposted by
Alex Guseman
Ardem Patapoutian
2 months ago
UCSD is holding a town hall with
@repscottpeters.bsky.social
this Wednesday to urge him to oppose proposed research funding cuts in the FY2026 budget, set for a vote in September. Please RSVP below and share widely. Everyone is welcome.
form.laborbase.org/251675765832...
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anyone have bead bath bead suggestions that are affordable? Or any hacks, can I go to wally world and by 500 worth of BB gun ammo (on my p-card) thats made of the same material?
2 months ago
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Thrilled to share this manuscript from my lab where we looked at how glycopolymers that compose the glycocalyx influence protein folding and protein-protein interactions via macromolecular crowding. TLDR: The Glycocalyx stabilizes protein folding and PPIs
www.biorxiv.org/content/10.1...
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Glycopolymers stabilize protein folding and protein-protein interactions via enthalpic interactions
Macromolecular crowding is ubiquitous to physiological environments, perturbing the thermodynamics and kinetics of proteins via excluded volume and nonspecific chemical interactions. While crowding ha...
https://www.biorxiv.org/content/10.1101/2025.08.11.669795v1
2 months ago
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Me citing my manuscript about to raise my PhD advisors H-index by at least 2 when this manuscript drops....
2 months ago
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These are some of the scientists supported by the mosaic grants in the described amicus brief. Thank you to ASM, FASEB and ASCB in joining ASBMB in supporting us.
asm.org/press-releas...
add a skeleton here at some point
3 months ago
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But the orange pumpkin told me that the tariffs wouldn't raise prices and that other countries would be paying for it...
3 months ago
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Roy running for senate makes me want to move back to NC to vote for him again.
add a skeleton here at some point
3 months ago
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Through the ups and downs of the job market, to starting my faculty career, to everything going on today. I could not have asked for a greater group of scientists to learn from, grow with, and call friends . Thank you.
@asbmb.bsky.social
#mosaicforever
3 months ago
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When work takes you back east. Sometimes you get lucky and get to visit the family at the lake!
3 months ago
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Raise your hand if you have already poisoned your ChatGPT pro to tell you what you want/how ANYTHING applies to your work without asking…. Btw it only took like a week and not that much use…
3 months ago
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not autocorrect trying to change mucin to muffin throughout my manuscript. Like word I know both are sugar filled but they are not the same!
3 months ago
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Sunday’s are for adventures with my better half (this time in nature) and grilling!
3 months ago
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Does sartorius costumer support suck for everyone or is it just me? I have been fighting them for over a month to 1.) get my BLI moved and 2.) buy tips for my BLI and i am getting nowhere. im like trying to spend >10k there and they dont want to buisness?
3 months ago
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congrats to all the new PDEP fellows! At this rate we are going to have to hold a La Jolla current and past PDEP fellows happy hour sometime...
add a skeleton here at some point
4 months ago
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New centrifuge was so excited to get in the lab it jumped off the truck!
4 months ago
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reposted by
Alex Guseman
Zandrea Ambrose, Ph.D.
4 months ago
Does anyone know of an immigration lawyer in Pennsylvania who may be willing to do some pro bono work for a student who is being detained by DHS? This student was finalizing their green card application and was taken a week ago. Please hit me up.
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Does anyone else have trouble with Sartorius ? im trying to buy things from them and they make me jump through a million hoops.
4 months ago
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me drops 5,000$ in consumable BLI tips, accidently orders two, *shrug* they will generate good data also me WTF WHY IS THE FRIDGE $700 UGH why do i need two.
4 months ago
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New lab logo, coming in hot!
4 months ago
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Guseman griddle works is cooking this morning !!
4 months ago
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New toy! Wife and I made smash burger tacos they were awesome!
4 months ago
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Is this to be replaced with Final_Final Scientific integrity policy of the NIH
add a skeleton here at some point
4 months ago
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Between this and the cuts to medicare/medicaid the trump admin is straight up lord farquading it up over here. Joni Ernst essentially said this not once, but twice.
add a skeleton here at some point
5 months ago
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We interrupt the regular scheduled beach pictures to enjoy the mountain side vineyards
5 months ago
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implen vs nanodrop? thoughts?
5 months ago
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This is the dumbest timeline. We are like 2 weeks from giving the plants gatorade because electrolytes are what they crave...
5 months ago
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So glad they let me do science here
5 months ago
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19F NMR FTW!
add a skeleton here at some point
5 months ago
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Finally high field 19F NMR capabilities have arrived at UCSD!
6 months ago
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Only a few more weeks !!!
6 months ago
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reposted by
Alex Guseman
Wyoming Wormboy
6 months ago
BTW. If you’re a scientist and are feeling hollowed out, depressed, fried, frustrated, confused, and simply exhausted by everything, I understand you. You are perfectly sane and you are not alone.
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Sundays are for the grill
6 months ago
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The average American has three friends ...
add a skeleton here at some point
6 months ago
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Foodieland adventures with the new PI crew!
6 months ago
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reposted by
Alex Guseman
American Society for Cell Biology
6 months ago
Unlawful grant terminations are harming young scientists and threatening innovation. ASCB joins leaders calling for immediate funding restoration.
www.ascb.org/society-news...
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Leading Life Science Organizations: Unlawful Grant Terminations Pose Grave Threat to America’s Innovation Pipeline - ASCB
Amicus Brief Filed in Support of Suit Calling for Immediate Funding Restoration WASHINGTON, DC – Four leading life science organizations, including the ASCB, filed an amicus brief today asking the cou...
https://www.ascb.org/society-news/leading-life-science-organizations-unlawful-grant-terminations-pose-grave-threat-to-americas-innovation-pipeline/
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Sen Kennedy trying to complain about overhead and then demonstrating that he has zero idea how overhead works. What a fucking scam of a senator, trying to push an argument that he doesn't understand the crux of.. at least learn how it works if you are going to legislate it...
6 months ago
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reposted by
Alex Guseman
Needhi Bhalla 💅🏽
6 months ago
“MOSAIC awardees were chosen using a definition of diversity beyond race, gender, and disability. It includes those who grew up in poor households or rural areas or were raised by parents who do not have college degrees.” 🧪
add a skeleton here at some point
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Saturday morning puppy snuggles
6 months ago
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reposted by
Alex Guseman
Vivien Maltez
6 months ago
Hey look, it’s me! Shout out to
@keystonesymposia.bsky.social
and the amazing 2025 Fellows. So honored to be part of this stellar group and be highlighted in this month’s blog!
urldefense.com/v3/__https:/...
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April Fellow's Spotlight on Dr. Vivien Maltez
Our April Fellows Spotlight goes to Dr. Vivien Maltez, PhD, is an Assistant Professor in the Division of Allergy, Immunology, and Rheumatology within the Department of Pediatrics at the University of ...
https://urldefense.com/v3/__https://keypoint.keystonesymposia.org/home/maltez__;!!LLK065n_VXAQ!h4p1JG2K_7k1IfOY-ToUU63liCa6HGG4hXHSGlwKjV-QjdLuuOXTjNKna0zG16J72aEjDZUN-SeqgCPsnaNIE95fuU5u$
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