Jon Davidow
@choisi.bsky.social
📤 843
đź“Ą 4449
đź“ť 7
PGY 4 Neurology, interested in
#consciousness
#coma
and
#AI
in
#Neurocriticalcare
reposted by
Jon Davidow
Earl K. Miller
4 days ago
The brain is more than spiking neurons. Astrocytes, a large fraction of cells, propagate electrical influences without spiking. And cortical neurons spike only intermittently. Electrical signals are continuous and across all cells.
#neuroscience
www.quantamagazine.org/once-thought...
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Once Thought To Support Neurons, Astrocytes Turn Out To Be in Charge | Quanta Magazine
New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest that neuron-only brain models, such as connectomes, leave out a crucial la...
https://www.quantamagazine.org/once-thought-to-support-neurons-astrocytes-turn-out-to-be-in-charge-20260130/
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Relevant to all fields of Neurology (and Medicine, as Dr. Okun points out), including recovery from acute brain injury.
add a skeleton here at some point
20 days ago
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reposted by
Jon Davidow
Neurocritical Care
2 months ago
Qin et al: Clinical Features and Outcomes in Adult Patients with Autoimmune Encephalitis Requiring Intensive Care: A Retrospective Cohort Study Link:
link.springer.com/ar...
@neurocritical
#neurocritcare
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reposted by
Jon Davidow
bioRxiv Neuroscience
3 months ago
"Awe-scillations": EEG spectral and complexity representations of awe
https://www.biorxiv.org/content/10.1101/2025.11.20.689403v1
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reposted by
Jon Davidow
The Picower Institute for Learning and Memory at MIT
3 months ago
Heard at
#SfN25
from
@earlkmiller.bsky.social
: Cognition and consciousness emerge from the dynamic organization of the cortex produced by traveling brain waves performing analog computations.
picower.mit.edu/news/brain-w...
#neuroscience
#consciousness
#cognition
@mitbcs.bsky.social
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Brain waves’ analog organization of cortex enables cognition and consciousness, MIT professor proposes at SfN
On neuroscience’s big stage Nov. 15, MIT Professor Earl K. Miller proposed that thought and consciousness emerge from the fast and flexible organization of the cortex produced by the analog computatio...
https://picower.mit.edu/news/brain-waves-analog-organization-cortex-enables-cognition-and-consciousness-mit-professor
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reposted by
Jon Davidow
Josh Barocas, MD â•ď¸Ź
3 months ago
The Erosion of Harm Reduction | New England Journal of Medicine
www.nejm.org/doi/full/10....
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The Erosion of Harm Reduction | NEJM
The U.S. administration has continuously chipped away at public health interventions addressing substance use disorders and the opioid crisis, including vital harm-reduction activities.
https://www.nejm.org/doi/full/10.1056/NEJMp2511727?query=WB
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reposted by
Jon Davidow
Elliot Murphy
3 months ago
Human cortical dynamics of auditory word form encoding
www.cell.com/neuron/fullt...
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Human cortical dynamics of auditory word form encoding
Zhang, Leonard, et al. use high-density direct human brain recordings to reveal how the superior temporal gyrus (STG) detects word boundaries in natural speech and encodes whole auditory word forms. N...
https://www.cell.com/neuron/fulltext/S0896-6273(25)00792-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627325007925%3Fshowall%3Dtrue
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reposted by
Jon Davidow
Marc L Seal
4 months ago
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans | PLOS Biology
journals.plos.org/plosbiology/...
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Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy by disconnecting a significant portion of the cortex. This study shows that the isolated cortex exhibits EEG patterns resem...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003060
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reposted by
Jon Davidow
Le Neuro (Institut-Hôpital neurologique de Montréal)
4 months ago
Today, a team of scientists led by Jordan DeKraker, Boris Bernhardt and Alan Evans published HippoMaps, an
#openaccess
toolbox and online data warehouse for the mapping and contextualization of subregional hippocampal data in the human brain. đź§
rdcu.be/eI1ye
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Lots of interesting implications…
add a skeleton here at some point
4 months ago
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reposted by
Jon Davidow
Intensive Care Medicine Journal
5 months ago
Switching from 1% to 2% propofol in ICU sedation cut greenhouse gas emissions, waste, and costs, with savings equal to over seven Paris–New York flights annually, showing concentration adjustment as a path to greener critical care.
zurl.co/DHWbi
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Extremely inspiring start to
#NCS2025
with a presentation of the RECOVER program and consortium, a beautiful multi-d approach to improve the clinical care of people in coma
www.med.upenn.edu/recover-prog...
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RECOVER Program Overview | Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) Program | Perelman School of Medicine at the University of Pennsylvania
Information about the Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) Program at the University of Pennsylvania.
https://www.med.upenn.edu/recover-program/
5 months ago
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Interesting work helping to move from the subjective to the objective in psychedelic science.
add a skeleton here at some point
5 months ago
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Practice changing systematic review and meta analysis, no evidence of symptomatic ICH with early DOAC:
www.thelancet.com/journals/lan...
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Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised contr...
For people with acute ischaemic stroke and atrial fibrillation, early DOAC initiation (within 4 days) reduced the risk of the composite outcome of recurrent ischaemic stroke, symptomatic intracerebral...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00439-8/fulltext
7 months ago
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reposted by
Jon Davidow
Nature Reviews Neurology
9 months ago
ICYMI: New online! Autoimmune encephalitis-associated epilepsy
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Autoimmune encephalitis-associated epilepsy
Nature Reviews Neurology, Published online: 02 May 2025; doi:10.1038/s41582-025-01089-4In this Perspective, the authors provide a detailed description of rare autoimmune encephalitic conditions that present with recurrent seizures that are resistant to immunotherapy, grouped under the term autoimmune encephalitis-associated epilepsy. The article considers the clinical characteristics and pathophysiological mechanisms of these conditions, alongside current knowledge of treatment and outcomes.
https://bit.ly/4lZTSWL
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reposted by
Jon Davidow
josh farkas đź’Š
10 months ago
generalized convulsive status epilepticus update: feels like it's time to add IV ketamine as a 2nd line agent before intubation 👇 thoughts/opinions? rationale explained here:
pubmed.ncbi.nlm.nih.gov/36609129/
evidence is accumulating eg,
pubmed.ncbi.nlm.nih.gov/37610640/
#EMIMCC
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Proud to share cases which might help to change the outcome for others
bmcneurol.biomedcentral.com/articles/10....
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Delayed diagnosis of basilar artery occlusion in a 28-year-old postpartum woman - BMC Neurology
Background Basilar artery strokes, which are often challenging to diagnose due to their diverse symptoms and uncommon occurrence, demand timely identification to mitigate severe consequences. Case pre...
https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-024-03927-2
about 1 year ago
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www.cell.com/cell/fulltex...
Lots of serotonergic neuroprotectantive agents to explore.
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Serotonin reduction in post-acute sequelae of viral infection
Post-viral syndromes are associated with serotonin reduction, which may contribute to the neurological and cognitive symptoms seen in individuals with Long COVID.
https://www.cell.com/cell/fulltext/S0092-8674(23)01034-6
about 1 year ago
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