Lisa Watt
@lisawatt.bsky.social
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PhD student @ EPFL 🇨🇭 in the Gräff lab 🧠🐁🧬 Epigenetics - Neuroscience - Memory
reposted by
Lisa Watt
Davide Martino Coda
5 days ago
🚨
@lisawatt.bsky.social
's paper is out! We uncovered an epigenetic ‘swing’ that tunes how neuronal ensembles capture memories in the brain 🧬🛝🧠. A project that I co-supervised with
@graeffjohannes.bsky.social
. Kudos to all authors!
onlinelibrary.wiley.com/doi/10.1002/...
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Manipulating Engram Histone Acetylation Alters Memory Consolidation
The epigenome provides the brain with a nucleus-templated form of plasticity that is of fundamental importance for learning and memory. Of the various types of epigenetic modifications, elevations in....
https://onlinelibrary.wiley.com/doi/10.1002/hipo.70041
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reposted by
Lisa Watt
Davide Martino Coda
10 days ago
🚨The paper from my postdoc in
@graeffjohannes.bsky.social
’s lab at
@epfl-brainmind.bsky.social
is out! We show that memories can be switched on and off by simply changing the « packaging » of DNA in neurons through epigenetic editing.
www.nature.com/articles/s41...
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Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics
CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.
https://www.nature.com/articles/s41588-025-02368-y
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