Can microglia be stimulated to help fight #Alzheimer’s disease (AD)? New work from the Gräff @graeffjohannes.bsky.social & Sanchez-Mut groups shows PM20D1, via its metabolite OLE, promotes microglial engagement with amyloid plaques and neuroprotection in AD models - doi.org/10.1038/s413...

New work by Simone Astori in Carmen Sandi's @carmensandi10.bsky.social lab shows that nucleus accumbens medium spiny neurons rapidly tune their excitability to mitochondrial energy shifts via K-ATP channels, linking neuronal bioenergetics to effort-related motivated behaviour doi.org/10.1038/s413...

Many motor tasks require precise coordination between multiple motor & sensory systems. New #Drosophila work by the @epfl-brainmind.bsky.social group of Pavan Ramdya reveals the centralized neural circuits necessary to solve antennal grooming synchronized motor-control - doi.org/10.1038/s414...

🧠 Carmen Sandi | Chica and Heinz Schaller Foundation Award Lecture 🌟 At #FENS2026, join Prof. Carmen Sandi, École Polytechnique Fédérale de Lausanne, on 9 July! 🔗 Meet all the speakers: buff.ly/1EBdiLL

Carl Petersen: Cortical circuits for whisker sensory perception—From barrel columns to brain-wide interactions doi.org/10.1016/j.co...

Two new @epfl-brainmind.bsky.social group reviews: The lab of Alexander Mathis @trackingskills.bsky.social: The behavior biopsy: Interpreting animal behavior as embodied, situated, and hierarchical doi.org/10.1016/j.co...

Many congratulations to @epfl-brainmind.bsky.social professor Gioele La Manno @gioelelamanno.bsky.social!

Novelty is not just about whats new, but also what feels new given past experience. New study from Sophia Becker in Wulfram Gerstner’s @epfl-brainmind.bsky.social lab posits a model showing how similarity between familiar and novel stimuli shapes exploration and learning - doi.org/10.1016/j.ne...

How does circuit structure shape neural activity? The lab of @epfl-brainmind.bsky.social Prof. Wulfram Gerstner shows that distinct neural circuits can produce similar low-dimensional dynamics, while retaining clear signatures in single neuron and population activity data: doi.org/10.1016/j.ne...

What if memory loss from aging or disease could be restored? The lab of @epfl-brainmind.bsky.social Professor Johannes Gräff @graeffjohannes.bsky.social shows that partial cellular reprogramming of engram neurons restores learning and memory to youthful levels in mice - doi.org/10.1016/j.ne...

When objects are close together, seeing details is harder 👉visual crowding. @epfl-brainmind.bsky.social prof. Michael Herzog's lab shows that a single nearby object barely affects perception, but many can aid or impede it, depending on alignment, challenging current theories doi.org/10.1177/1747...

Understanding how brain regions communicate to shape behavior requires realistic models. The @epfl-brainmind.bsky.social labs of Carl Petersen & Wulfram Gerstner show that adding biological features to neural networks improves the prediction of brain responses to stimulation doi.org/10.7554/eLif...

Identifying individual wild animals is key for conservation. The lab of @epfl-brainmind.bsky.social professor Alexander Mathis @trackingskills.bsky.social uses AI and images of Alaskan brown bears to non-invasively identify individuals & their behavior across seasons & years doi.org/10.1016/j.cu...

EPFL ELISIR apps now open go.epfl.ch/ELISIR. Fantastic opportunity for young neuroscientists to start an independent lab right after PhD, just like @epfl-brainmind.bsky.social ELISIR group leaders @jamespriestley.bsky.social & @ashleymaynard.bsky.social. www.youtube.com/watch?v=qjPD... 👉 April 1 26

@epfl-brainmind.bsky.social professor Michael Herzog's lab carried out a simulation study to identify how many visual elements are needed for object recognition by cortical visual prostheses, establishing a practical lower-bound phosphene estimate for more effective function: doi.org/10.1016/j.vi...

The group of @epfl-brainmind.bsky.social professor Johannes Gräff @graeffjohannes.bsky.social show that altering histone acetylation enhances fear memory recall, while reducing it weakens recall, demonstrating a functional link to the activity of memory engram cells: doi.org/10.1002/hipo...

Can memories be switched on and off, as in 'Eternal Sunshine of the Spotless Mind'? The team of @epfl-brainmind.bsky.social professor Johannes Gräff @graeffjohannes.bsky.social use CRISPR-based epigenetic control of Arc to reduce or enhance memories in mice: www.nature.com/articles/s41...

Prof. Carmen Sandi's @carmensandi10.bsky.social group reviews the potential for modulation of metabolic pathways to treat anorexia nervosa - www.nature.com/articles/s41...

The Chica and Heinz Schaller Foundation and #FENS are thrilled to announce the winner of the Chica and Heinz Schaller Foundation Award in Translational Neuroscience 2026: Prof. Carmen Sandi (@carmensandi10.bsky.social)! 🧠 👉 https://loom.ly/Uh0TghU

The group of @epfl-brainmind.bsky.social professor Henry Markram shows that glucose-dependent N-glycosylation drives variability in the Kv3.4 ion channel, regulating activity & cell excitability. N-glycosylation regulation may link neurological disorders & glucose metabolism: doi.org/10.1016/j.is...

How do we weigh curiosity, effort, and reward? The labs of @epfl-brainmind.bsky.social professors Wulfram Gerstner & Michael Herzog find humans overexplore when seeking monetary reward, drawn to novel options even when more exploration offers no advantage. Explore the paper 👉 doi.org/10.1073/pnas...

New study by the group of @epfl-brainmind.bsky.social professor Carmen Sandi @carmensandi10.bsky.social shows that three mitochondrial associated metabolites in the dmPFC/dACC brain region can predict mental effort choices - www.nature.com/articles/s41...

Last chance to apply for the EPFL Neuroscience tenure track assistant professor faculty position - the deadline is tomorrow October 1. Submit now! go.epfl.ch/neurofaculty.

Group of @epfl-brainmind.bsky.social professor Gioele La Manno @gioelelamanno.bsky.social + Giovanni D’Angelo lab, use MS imaging & a novel analytical framework to map the 4D distribution >100 lipids in zebrafish & find unexpected distributions 👉 unknown developmental roles - doi.org/10.1038/s415...

Cataract surgery is the most common surgical procedure worldwide. The lab of @epfl-brainmind.bsky.social professor Michael Herzog shows that in addition to visual acuity, cataracts also affect low-level visual processing, which should be considered in ophthalmic clinical care doi.org/10.1167/jov....

The group of @epfl-brainmind.bsky.social professor Carmen Sandi @carmensandi10.bsky.social shows Corticotropin-releasing Hormone (CRH) modulates the thalamic reticular nucleus brain region to affect sleep, linking CRH with sleep impairment due to stress and anxiety- www.nature.com/articles/s41...

@epfl-brainmind.bsky.social Prof. Carmen Sandi's lab @carmensandi10.bsky.social show Urolithin A (UA), a gut microbiota-derived metabolite, can alleviate anxiety in rodents including behaviour, mitochondria & neuronal features. UA could be a new treatment for chronic anxiety doi.org/10.1016/j.bi...

The group of @epfl-brainmind.bsky.social Prof. Michael Herzog (also + @carmensandi10.bsky.social) show that human social dominance, a key social interaction factor, is a stable personality trait, has reliable specific brain EEG markers which in females mirror those in males doi.org/10.1016/j.is...

Action potential 👉 3 faculty opportunities to join EPFL neuroscience 1. Tenure Track Assistant Professor in Neuroscience go.epfl.ch/neurofaculty, 2. Tenure Track Assistant Professor in Life Sciences Engineering, or 3. Associate Professor (tenured) in Life Sciences Engineering go.epfl.ch/LSEfaculty

We are happy to announce an opening for a Tenure Track Assistant Professor Faculty Position in Neuroscience at EPFL. Join our groups working on cellular & circuit neuroscience & neurocomputation - go.epfl.ch/brain. Application deadline is Oct 1 2025. Apply now 👉 go.epfl.ch/neurofaculty

blu.ski/@epfl-brainmind professor Michael Herzog & team show that while older adults perform initially less efficiently in reinforcement learning tasks, given sufficient trials, they could perform as well as young adults. 👉 ageing does not universally impair performance: doi.org/10.1007/s002...

New tool CellSeg3D, from the group of blu.ski/@epfl-brainmind professor Mackenzie Mathis @trackingactions.bsky.social enables self-supervised 3D cell segmentation in fluorescent microscopy,👇 labeling time & 👆quantitative analysis - paper: elifesciences.org/articles/99848 news: tinyurl.com/y2hpmbb9

Amazing hierarchical & multimodal wild animal behavior recognition + segmentation from the group of @epfl-brainmind.bsky.social professor Alexander Mathis @trackingskills.bsky.social. See the demo: www.youtube.com/watch?v=hZjk... story: actu.epfl.ch/news/ai-moni... & paper: arxiv.org/html/2503.18...

The @epfl-brainmind.bsky.social lab of Gioele La Manno @gioelelamanno.bsky.social together with @maweigert.bsky.social develop Spotiflow, a deep learning method for subpixel-accurate spot detection in 2D & 3D images, a crucial tool for many life-science applications www.nature.com/articles/s41...

The lab of @epfl-brainmind.bsky.social professor Alexander Mathis @trackingskills.bsky.social show that task-driven models of proprioception, similar to proprioception in vivo, have illusions & that the vibration frequency of primary afferents alone can explain them - doi.org/10.1113/EP09....

Congratulations to @epfl-brainmind.bsky.social professor @carmensandi10.bsky.social on winning the 2025 ECNP Neuropsychopharmacology Award - www.ecnp.eu/news/press-o...

EEG measures are often used to explain differences in performance between groups, however the lab of @epfl-brainmind.bsky.social professor Michael Herzog, using EEG & visual tests, shows these measures mainly reflect stable traits of participants rather than test performance doi.org/10.1016/j.bb...

Delighted to see our new collaboration on ecological neuroscience 🧩🌿🧠 announced today! A huge ❤️🙏🏼 to @simonsfoundation.org I’m so excited by this theory-driven question. It’s core to our research on adaptive intelligence & sensorimotor systems 🙌 #SCENE www.simonsfoundation.org/2025/04/24/s...

Really thrilled to be part of the Simons collaboration for ecological neuroscience - www.simonsfoundation.org/neuroscience...

@epfl-brainmind.bsky.social professor Pavan Ramdya discusses how studies of #drosophila can inspire novel robots. - actu.epfl.ch/news/fruit-f...

Hiring! Postdoc position in Human Metabolism! Join us to explore the metabolic underpinnings of human brain & behavior; focusing on anxiety & motivation Outstanding interdisciplinary environment @epfl-brainmind.bsky.social at EPFL in Lausanne Switzerland Info here: www.fens.org/careers/job-...

New editorial focus article by @epfl-brainmind.bsky.social professor Alexander Mathis @trackingskills.bsky.social together with Andy Bonnetto - Climbing out of the lab: Studying motor planning and coarticulation in the climbing gym doi.org/10.1152/jn.0...

Many congratulations to lab member Medha Raman for winning the EPFL final of MT180 - My Thesis in 180 seconds

One week left to register for the 2025 NeuroLeman-Chen-FENS summer school. Spend September learning by the lake! A joint initiative of the Tianqiao and Chrissy Chen Institute, NeuroLéman and @fens.org - www.fens.org/news-activit...

Applications for PhD positions in neuroscience at EPFL are now being accepted www.epfl.ch/education/ph.... Join the exciting research programs of the @trackingskills.bsky.social, @trackingactions.bsky.social, @mccabelab.org, Carl Petersen or Pavan Ramdya groups. Deadline April 15 2025 - Apply today!

Thank you to Target ALS for highlighting the work on #ALS in our laboratory together with Bernard Schneider and Sabine Liebscher. We are very grateful for your funding and unflagging support - www.targetals.org/2025/03/04/i...

New study by @epfl-brainmind.bsky.social professor Carl Petersen's group shows that cortical motor maps, which organize voluntary motor control, can be decomposed into cell-class defined modules with specific plasticity. These modules may interact to control movement - doi.org/10.1016/j.cu...

We are delighted to welcome Ashley Mayard to the @epfl-brainmind.bsky.social as a new ELISIR fellow. Ashley's lab will explore the mechanisms underlying brain regeneration across species with the aim to unlock the capacity to recover from brain injuries. More here soon - www.epfl.ch/labs/gr-mayn...

Watch @epfl-brainmind.bsky.social professor Pavan Ramdya describe how investigation of #Drosophila can aid in the development of next-generation biologically inspired intelligent machines and robots: www.youtube.com/watch?v=kFV6...

New study by @epfl-brainmind.bsky.social professor Carmen Sandi's group @carmensandi10.bsky.social shows mitochondria can regulate neuronal ciliary structures, potentially linking mitochondrial dysfunction in neuropsychiatric disorders to disrupted neuronal ciliary signaling doi.org/10.1113/JP28...