Mary Oliver, Xenia Davis & @julia-bohannon.bsky.social @vanderbilt.edu @vumedicine.bsky.social present their new Review - "Tissue context as a determinant of #TrainedInnateImmunity: a conserved molecular toolkit with divergent functional outputs"

Daniel Butler @lund-university.bsky.social presents a comprehensive update on #Granulomas and how recent #Singlecell and #Spatial #Transcriptomics has improved our understanding of these dynamic immune niches

This month’s FREE FOR ALL seminar is on May 27th 1pm-2pm ET. Dr. Andres Hidalgo from Yale University will present on "Understanding Neutrophils". Get more info and register here: www.leukocytebiology.org/index.php?op...

Mihir Atreya & Basilia Zingarelli @cincychildrens.bsky.social @cincyresearch.bsky.social present a News & Views article discussing a recent study in @natimmunol.nature.com - "Mapping the #Sepsis immune landscape across age and source of infection: lessons from #Singlecell #Multiomics"

Sandrine Huot, Paul Fortin, Cynthia Laflamme & Marc Pouliot @chudequebec.bsky.social @crchudequebec.bsky.social report that "#Neutrophil #FcγRI expression as a determinant of oxidative responses in human blood"

Jingfei Zhang, Zhixuan Wu & Ru Zhang use transcriptome sequencing to explore the regulatory mechanism of #EphedraSinica Stapf on the TGF-β/Smad3/GATA3 pathway

New Review from Asmaa Mahmoud, Maria Colombatti Olivieri, John Bannantine & Gaber Abdellrazeq - "#Neutrophil biology and fate reprogramming in bacterial infections: mechanisms, plasticity, and therapeutic targeting"

Friday is the deadline for submitting an image for our contest! More info in the link below

Di Yu, Shaoyi He and colleagues use weighted gene coexpression network analysis (#WGCNA) and #MachineLearning identify mitochondria programmed cell death-related genes as diagnostic biomarkers for #SepticShock

Chunjin Ke, Zhiquan Hu, Chunguang Yang and colleagues review the role of lymphocyte subsets in the diagnosis, treatment, and prognosis of #ProstateCancer - "Lymphocyte subsets: new hope for noninvasive biomarkers of prostate cancer"

Yuxi Liu, Jingang Song, Chao Wei and colleagues show that Mendelian randomization supports a gut-immune-joint axis in #Osteoarthritis (OA), linking specific gut microbial genera to OA through immune-cell traits that may serve as therapeutic targets

Catherine Moscinski, Christopher Born & Daithi Heffernan @brown.edu present their Review - "The role of #DuffyAntigen receptor for #Chemokines in acute respiratory distress syndrome (#ARDS)"

William Mitchell, Jacques Thibodeau and colleagues @umontreal.ca @umontreal-en.bsky.social present "A biotin ligation assay reveals a complex proxiome for #HLA-A2 and implicates #MIA3 in cell surface expression of #MHC class I molecules"

Xiaoying Zhao, Jiang Cheng, Weiwei Zheng & colleagues report that "#CCDC137 stabilizes #S100A6 to activate the #PI3K/AKT pathway and drive acute myeloid #leukemia progression"

Paul Jenkins, Pascale Pescher, Gerald Späth and colleagues @pasteur.fr @upcite.bsky.social show that "Intrinsic differences in hamster and mouse #Macrophage biology correlate with susceptibility to #Leishmaniadonovani infection"

Kristian Antonsen and colleagues @au.dk report that "Human #Macrophage #Phagocytosis of #LungCancer cells induced by #CD47 blockade is augmented after knockdown of phagocytosis checkpoints mediated by siRNA-loaded #LipidNanoparticles"

The new Review from Yuande Wang & Heping Xu presents an integrative spatiotemporal and physiological framework that explains how dynamic microenvironmental cues drive intestinal #Eosinophil adaptation

The April 2026 Issue of #JLB starts with "#SpatialProfiling reveals complex cellular responses of anti-IL5 treatment with #Mepolizumab in eosinophilic chronic #Rhinosinusitis with nasal polyposis" by Nicholas West and colleagues @griffith.edu.au

Romário Mascarenhas, Geraldo Passos and colleagues @uspoficial.bsky.social report "Single-cell RNA-seq of in vitro–cultured medullary thymic #EpithelialCells reveals a preserved differentiation trajectory under #Aire deficiency"

New data from Mary-Elizabeth Sheridan, Duale Ahmed and colleagues from the lab of Edana Cassol @carleton.ca - "Mitochondrial electron transport chain modulation orchestrates divergent #TLR3 and #TLR7 responses"

Anna Nicolela and colleagues from the @jeanetteeb.bsky.social lab @bhcri.bsky.social show that "Adenosine drives suppression of CD16low #NKcell responses against #HGSC via #NKG2A:#HLA-E interactions"

New data from Behjatolah Monzavi-Karbassi and colleagues @uamshealth.bsky.social show that "Class A scavenger receptors promote tumor progression and induce a unique #Macrophage phenotype in a mouse model of spontaneous #BreastCancer"

In their recent News & Views article in #JLB, Shuo Geng & Liwu Li @virginiatech.bsky.social discuss evidence linking #LongCOVID to activation of #Proinflammatory and #ImmuneExhaustion pathways

Olga-Demetra Biziotis, Jonathan Bramson, Theodoros Tsakiridis and colleagues @mcmasteruniversity.bsky.social show that "HER2-specific synthetic antigen receptor T cell therapy synergizes with radiotherapy to provide improved antitumor efficacy in non-small cell lung cancer"

Brie Trusiano, Rebekah Smith, Cassandra Poole and colleagues from the lab of Irving Coy Allen @virginiatech.bsky.social report that "Loss of NF-κB-inducing kinase (NIK) affects eosinophilopoiesis in a murine model of #HypereosinophilicSyndrome"

It’s an #Eosinophil double feature! Dive into TWO back-to-back Reviews in the March 2026 issue of #JLB 🔬

Sara Monaci and colleagues identify a "Novel role of Hippo effector #YAP1 as a rheostat controlling #Inflammation in #DendriticCells"

Abel Ang, Albena Dinkova-Kostova, John Hayes and colleagues @dundee.ac.uk report that "The CNC-bZIP transcription factor #Nrf2 controls expression of matrix metalloproteases in murine #Macrophages"

New data from Kristina Hinman, Jason Machan & Craig Lefort @brown.edu shows "#Neutrophil progenitor cell therapy rescues host defense against #StaphylococcusAureus in murine #ChronicGranulomatousDisease"

Starting off our March 2026 issue of #JLB - "Sirtuin 1 is an endogenous #NETosis inhibitor that becomes dysfunctional in #Diabetes" by Liang De Wang & colleagues

In Vol 1 2026 of @leukocytebiology.bsky.social #iSLB newsletter, read THREE #JLB Author Interviews! www.leukocytebiology.org/assets/docs/...

Register now for our next free webinar by Dr. Shruti Rawal on "A microRNA mediated regulation of macrophage immunometabolism in diabetes-associated atherosclerosis" www.leukocytebiology.org/index.php?op...

Haobei Ran, Lipan Zhang and colleagues report that "Single-cell transcriptomic analysis reveals RNA-binding protein dysregulation in #ImmuneCheckpointInhibitor –induced #Colitis"

Read the new Review from Olena Zaitseva and Harald Wajant - "#TNFR2-targeting biologics: Molecular mode of action, possible applications, and future developments"

Mirushe Miftari and Bernt Walther @unibergen.bsky.social report that "Noneosinophilic #Leukolectin proteins occur in cytoplasmic granules in some human leukocytes"

New data from Holly Linley, Amy Saunders and colleagues @lydiabeckeriii.bsky.social @manchester.ac.uk shows that "#CD200R1 promotes the development of murine #γδ17 #Tcells"

@christyclutter.bsky.social & @danieltleung.bsky.social at @uofuhealth.bsky.social discuss a recent landmark study in mucosal-associated invariant T (#MAIT) cell biology! Read the News and Views article now - "Tracing #MR1 expression across tissues to find the perfect MAIT"

Work from Ed Lavelle lab @tcddublin.bsky.social @tbsi-tcd.bsky.social led by Roisin Lynch shows that "Biodegradable microparticles promote anti-inflammatory innate immune memory through a size- and #mTOR-dependent process"

Jochen Mattner @fau.de provides a comprehensive Review of #CD101 - "CD101: A versatile molecule associated with #Immunoregulatory and #Antimicrobial functions"

New data from Elena Lonina, Martin Pelletier and colleagues @ulaval.ca @crchudequebec.bsky.social - "The selective estrogen receptor modulator #Bazedoxifene affects the #Metabolism and functions of human #Neutrophils"

Yuran Miao, Liwan Lin, Zhixi Chen and colleagues show that "Leukocyte immunoglobulin-like receptor subfamily B member 1 (#LILRB1) expression defines CD8+ #Tcell #Exhaustion in acute myeloid #Leukemia"

Emma Maxwell, David Hume, Sebastien Jacquelin and colleagues report that "A conserved upstream element in the mouse #Csf1r locus contributes to transcription in hematopoietic and trophoblast cells"

Zhaoxing Wu and colleagues report that "Targeting CaMKIIδ overcomes therapy resistance in acute myeloid #Leukemia by suppressing the #STAT3/#CDK6/#BCL-2 survival axis"

New research from Bayan Alhaddad, Theresa Wrynn and colleagues @ubuffalo.bsky.social - "IL-36 mediates immune activation in #Sjögren’s disease and may represent a novel biomarker of disease"

Leslie Chan @stanfordimmunology.bsky.social, Catherine Blish @blishlab.bsky.social and colleagues @stanfordmedicine.bsky.social identify #Interferon activation and #NKG2D expression as key determinants of #NKcell antibody-dependent cellular cytotoxicity (#ADCC) in #SARS-CoV-2 infection

Daniel Kim, Ramizah Syahirah, Qing Deng and colleagues @cancer-inst-purdue.bsky.social report that #RABEP1 is necessary for #Neutrophil migration - "RABEP1 regulates neutrophil migration via endosomal recycling and actin polymerization"

New findings from Shaunna Simmons, Annabel Rivera & @elsaawesomepmns.bsky.social @ubuffalo.bsky.social - "Basal activation of #ERK1/2 blunts the antimicrobial activity of #Neutrophils from old hosts against antibody-opsonized #StreptococcusPneumoniae"

New data from Heidi Rysan, @rdekoter.bsky.social and colleagues @schulichmeddent.bsky.social - "H195Y mutation of #IKZF3 identified in a mouse model of precursor #Bcell acute lymphoblastic #Leukemia impairs transcriptional repression activity and increases protein stability"

Li and colleagues uncover new insights into skin #Macrophage formation - "#ICAM-1 and vascular matrices coordinate skin S1 macrophage formation from blood #PDGFRα lineage #Monocyte"

"#Neutrophils and the #NLRP3 #Inflammasome: a tale of #Proteases, #Kinases, and #Inflammation" - read the new Review by Vinicius Leal @uspoficial.bsky.social & Alexander Weber @unituebingen.bsky.social