Jochem Smit
@jhsmit.bsky.social
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Biophysics; protein dynamics/folding using smFRET and HDX-MS.
https://jhsmit.org/
Just updated my hikemap with our Ardennes hikes!🗺️🥾 One of the perks of living in Belgium: epic trails basically in your backyard 🇧🇪🌳 There are a couple of cool two-day hikes here as well which were (rather painful😅) training sessions for our Norway adventure 🇳🇴🏔️
jhsmit.org/hikes/hikema...
#hiking
5 months ago
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Such a pleasure to define HDX-MS states directly in VS code!
#solara
#hdxms-datasets
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7 months ago
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Having some fun with 3DPGA & kingdon (GA library for python) in ipymolstar! Geometric Algebra feels like magic 🪄; I don't understand it but surely its very powerful 💪 Live example on pycafe:
py.cafe/jhsmit/ipymo...
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8 months ago
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New release for
#ipymolstar
: I've added a widget for the amazing and very powerful MolViewSpec. This allows you to control the camera📷from python🐍, as well as all other molviewspec features 🎉 ipymolstar repo:
github.com/jhsmit/ipymo...
Molviewspec:
molstar.org/mol-view-spec/
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8 months ago
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reposted by
Jochem Smit
Jörg Enderlein
9 months ago
I was invited, for July, to a scienctific meeting in Telluride (Colorado). I was told it is a wonderful place for a conference, and I was very much looking forward to an exciting meeting in a fantastic environment. I have just canceled my participation, despite having booked already everything.
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French scientist denied US entry after phone messages critical of Trump found
France’s research minister said the scientist was traveling to Houston for a conference when his phone was searched
https://www.theguardian.com/us-news/2025/mar/19/trump-musk-french-scientist-detained
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reposted by
Jochem Smit
Eve Seuntjens
10 months ago
Hi folks, I would like to know which EU universities are willing or planning to organise
#standupforscience
activities in solidarity with US scientists Please contact me if you are. Thanks for reposting!
add a skeleton here at some point
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reposted by
Jochem Smit
Vatnik Soup
10 months ago
In today’s Vatnik Soup, I’ll introduce how the Elon Musk’s Election Interference Machine™ (EIM) works. Since Musk and his broligarch allies won the presidency for Trump, they’ve now harnessed the machine to interfere in European elections, including the ones in Germany and Romania. 1/23
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I have some exciting news to share!! A cute little boy arrived in our lives early december Mom & dad are very tired but happy 😃 birth card illustration by Tintenbaum
tintenbaum.com
11 months ago
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Here's a neat way to share you protein-annotated data 🚀🧪 Upload your .csv with residue/value data, select data column, colormap and norm to interactively color your protein model. Then, add title/description and click the button to open a shareable view with url-encoded data and settings.
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about 1 year ago
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#ipymolstar
v0.0.9: Added click interactions try it on pycafé:
py.cafe/jhsmit/ipymo...
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about 1 year ago
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Two-way tertiary/primary structure hover and highlight with
#ipymolstar
and
#altair
Try it on pycafe:
py.cafe/jhsmit/ipymo...
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about 1 year ago
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reposted by
Jochem Smit
Thiago Carvalho
about 1 year ago
"In the Netherlands — where the Party for Freedom (PVV), led by the anti-Islam firebrand Geert Wilders, entered a coalition government in July — researchers are bracing for €1 billion (US$1.1 billion) in cuts to the budget, the worst in decades."
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Far-right governments seek to cut billions of euros from research in Europe
Anti-immigration parties are pushing policies that are hostile or indifferent towards science.
https://www.nature.com/articles/d41586-024-03506-y
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By popular demand: How much monomer/dimer/tetramer are formed at steady-state given the two kds and the total concentration of protomer? 🧐
py.cafe/jhsmit/tetra...
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PyCafe - Solara - Tetramerization Kinetics Analysis
PyCafe: get your daily fix of Python!
https://py.cafe/jhsmit/tetramerization-kinetics-analysis
over 1 year ago
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I've created this
#solara
app where you can drag & drop your
#alphafold3
.zip file and switch between chain color or plddt colors. Includes 'spin' and theme toggle for maximal viewing pleasure. The screenshot below shows the elusive SecA2/SecB4 complex.
huggingface.co/spaces/Jhsmi...
over 1 year ago
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New in
#ipymolstar
version 0.0.4: directly load your local data files `pip install "ipymolstar==0.0.4"`
github.com/Jhsmit/ipymo...
over 1 year ago
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reposted by
Jochem Smit
Arjen Dijkstra
over 1 year ago
Dit is en blijft racisme. Iemand uit Afrika mag geen mening hebben over het Fries en komt gewoon geld graaien. Ik vind het ontluisterend dat dit op tv is en blijft.
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I've created my first widget with
#anywidget
! Its called `ipymolstar` and allows visualization of proteins or molecules interactively from python. check out the video below or try it live on ploomber:
youtu.be/Syra-DCtQkA
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ipymolstar
demo of ipymolstar in a solara app ipymolstar source: https://github.com/Jhsmit/ipymolstar example app source and live demo: https://github.com/Jhsmit/ploomber-solara-ipymolstar
https://youtu.be/Syra-DCtQkA
over 1 year ago
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reposted by
Jochem Smit
Anthony Vecchiarelli
almost 2 years ago
Interested in the mechanisms driving subcellular organization in bacteria? The Vecchiarelli lab has a postdoc position available!
docs.google.com/document/d/1...
Plz RT!
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