Toszka Bohn
@toszkabohn.bsky.social
📤 31
📥 47
📝 2
Group Leader in Mainz, Interested in Tumor Immunology, Tumor Acidosis and Immunotherapy
reposted by
Toszka Bohn
Nature
about 1 month ago
Nature research paper: Ligand-specific activation trajectories dictate GPCR signalling in cells
go.nature.com/45R1og5
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Ligand-specific activation trajectories dictate GPCR signalling in cells - Nature
Different agonists produce equilibria of at least four distinct active states of the G-protein-bound M2 muscarinic acetylcholine receptor, each with a different ability to activate G proteins.
https://go.nature.com/45R1og5
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reposted by
Toszka Bohn
Johannes Gutenberg-Universität Mainz
about 2 months ago
Großer Forschungserfolg der
#UnimedizinMainz
zur Rezeptoraktivierung in lebenden Zellen: Pharmakologe Andreas Bock entwickelt Biosensoren, die Strukturänderungen von Rezeptoren in Echtzeit sichtbar machen 👉
www.unimedizin-mainz.de/newsroom/neui…
#Pharmakologie
ie
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reposted by
Toszka Bohn
Deutsche Forschungsgemeinschaft
3 months ago
Die
#DFG
fördert zur weiteren Stärkung der
#Spitzenforschung
an den Hochschulen 9 neue
#Sonderforschungsbereiche
(SFB). Die Themen reichen von pilzbasierten Baumaterialien über Autoimmunkrankheiten bis zu molekularer Bor-Chemie. Einzelheiten 👉
www.dfg.de/de/service/p...
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reposted by
Toszka Bohn
Katrin Pape
6 months ago
Excited to see our paper on the CD5 signalling pathway in Th17 cells and its role in
#MultipleSclerosis
out in
@brain1878.bsky.social
today. Thanks to everyone involved in this great team work!
@neurologymainz.bsky.social
@toszkabohn.bsky.social
#ImmunoSky
academic.oup.com/brain/advanc...
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Role of CD5 signalling for pro-inflammatory Th17 response in multiple sclerosis
Pape et al. link the CD5-CK2-STAT3 signalling pathway to both inflammation and effector function in multiple sclerosis, using a multi-modal approach that c
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaf268/8240838?searchresult=1
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