we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social

Nuclear rupture in confined cell migration triggers nuclear actin polymerization to limit chromatin leakage DDR sensor ATR protects against nuclear envelope rupture via formin phosphorylation inducing F-actin formation Christos Kamaras et al @grosselab.bsky.social www.embopress.org/doi/full/10....