Super excited that our two companion papers on saturation genome editing (SGE) of RNU4-2 and discovery of a novel recessive neurodevelopmental disorder (NDD) were published yesterday 🥳 SGE experiment: www.nature.com/articles/s41... Recessive NDD characterisation: www.nature.com/articles/s41... 🧵

@nhs.uk this may be for you

@england.nhs.uk Do not like the new NHS app at all. Quite difficult to get to look at details of person one cares for, where actually most of my traffic happens.

The Large Hadron Collider just produced a never-before-seen particle made of charm and down quarks

I would like to know what concerned and horrified “ordinary” people, could do to change how the world is run today. There is an astonishing feeling of “emperor’s new clothes” scenario where everyone, including me, says and does nothing about the illegal and unethical actions of deranged leaders

Science and Civilisation lecture @royalsociety.org : ERC President Maria Leptin gave a spirited and inspiring talk about maintaining academic freedom and knowledge progression. One essential component is maintenance of diversity of thought and people to keep new ideas flowing

@metoffice.gov.uk don’t like the new App at all. The old one was much better. For one thing it says that my location is Chelsea when I am in old Clapham. Nothing about Storms in Spain when I check Granada and Cordoba where I am bound soon

Pleasing picture and interesting to compare with the work of Anna Ancher currently on show at Dulwich Picture Gallery www.dulwichpicturegallery.org.uk/whats-on/ann...

Connections Puzzle #889 🟦🟦🟦🟦 🟩🟩🟩🟩 🟪🟨🟨🟨 🟨🟨🟨🟨 🟪🟪🟪🟪 Not often this works so well

What a fantastic icon, such focus and dedication. And she was an immigrant. So many countries have benefited from the fresh insights and out-of-the-box ideas of immigrants.

@bsgmofficial.bsky.social enjoyed an excellent morning of talks at #BSGM2025. Fantastic progress in medical genetics during my career. Feel as excited about the ideas and new findings as I was in the 1989s! So many more genetic components of diseases now understood. Therapy techniques now emerging

After this excellent meeting I am much clearer about why the question about newborn genome screening is not simply "Will it save some lives?" It would be great if it was, but that's not how it works.

It was a very good discussion. Thanks to BBC Sounds I listened while cooking dinner

@girtoncollege.bsky.social Have just spent a wonderful day at Girton celebrating 60 years since first arriving there. So many memories come flooding back. Great to hear what interesting and useful lives we have all led.

Come to a great free @adelphigenetics.bsky.social meeting about complexities of population screening, @royalsociety.org Thu 23 October. Register adelphigenetics.org/events/annua...

Come to a great free @adelphigenetics.bsky.social meeting about complexities of population screening, @royalsociety.org Thu 23 October. Register adelphigenetics.org/events/annua...

Wordle 1,522 2/6 🟨⬜⬜🟨🟩 🟩🟩🟩🟩🟩 WordleBot Skill 99/99 Luck 99/99 Surprisingly cheering

Wordle 1,509 2/6 🟩🟩🟨⬜⬜ 🟩🟩🟩🟩🟩 WordleBot Skill 99/99 Luck 99/99 Skill and luck. What more can I ask for?

A great step for mankind!

Our Faraday Discovery Fellowships Accelerated International Route is now open for applications, providing a fast-track option for attracting mid-career researchers looking to relocate to the UK from overseas, providing up to £4m over a five-year period. #RSGrants

Find out more about the scheme on our website: royalsociety.org/grants/farad...

About to enjoy second day @royalsociety.org meeting on “The future of scientific publishing”. Lots of interesting concepts and problems as well as good progress. Just hearing how important preprints were for scientific progress on COVID during pandemic. But reader knowledge and vigilance critical

🌳 Dame Judi Dench is calling for the return of ancient woodlands. Will you sign the petition to help restore the Ghost Woods and protect our green spaces for future generations? you.38degrees.org.uk/petitions/br...

@adelphigenetics.bsky.social annual conference on hot topic of Population Genomic screening will take place on Thursday 23 October 2025. Free to attend but must book adelphigenetics.org/events/annua... or www.eventbrite.com/e/population...

I have a lovely lovage soup recipe but no lovage since we moved from Edinburgh. It is too rampant for small London garden. After touching the leaves your hands smell of mild fragrant curry. Have read that it is secret ingredient of Knorr cubes

It is wonderful to see the successes and achievements of Royal Society funding recipients. One of their major contributions is the training of subsequent generations of scientists, but they continue to make huge contributions to science and society many decades after support by @royalsociety.org

🎉 Congratulations to Dr Yukun Zhou (@ucleye.bsky.social) on receiving the prestigious Wellcome Early Career Award! This 5-year fellowship will support his research on using AI for faster diagnoses and personalised care. buff.ly/gP2qW3A

This is better from the incoming RS president but they need to be *much* more robust in enacting their code of conduct. Otherwise what’s the point?

NDAs can silence victims of abuse & harassment. Let's change this! Sign the petition to ensure the Employment Rights Bill bans NDAs in cases of misconduct. #StopAbusiveNDAs #EmploymentRightsBill you.38degrees.org.uk/petitions/st...

I agree strongly with what @chrischirp.bsky.social says in this thread

Aunt Lydia in the Handmaid's Tale says: “There is more than one kind of freedom, freedom to and freedom from. In the days of anarchy, it was freedom to. Now you are being given freedom from.” Where freedom from ends up is Gilead. I want freedom to. Always and forever freedom to.

Old North Church in Boston last night on the 250th anniversary of Paul Revere's ride.

Looking forward to the videos

NDAs can silence victims of abuse & harassment. Let's change this! Sign the petition to ensure the Employment Rights Bill bans NDAs in cases of misconduct. #StopAbusiveNDAs #EmploymentRightsBill you.38degrees.org.uk/petitions/st...

It always boggles my mind that I, a journalist, am expressly forbidden from trading stocks, but members of Congress, with vastly greater knowledge of market-moving news, are allowed to profit by front-running markets, and so may profit by in essence stealing from the public they represent.

Lovely sunny day. Just back from Zumba

So have just got to the explosive phase?

See the dip in the solar power generation at the time of the partial eclipse from a friend’s solar panels

“Columbia was just such a warning,” he said. “I just became very worried because I didn’t see a strong enough reaction in other universities .... I see Yale trying not to be a target. That’s a losing strategy.” Yale Professor who Studies Fascism Flees to Canada www.theguardian.com/us-news/2025...

Sad but true: Columbia has inspired scholars to flee US academia completely. "Jason Stanley ... said he finally accepted Toronto’s long-standing offer after seeing Columbia University 'completely collapse and give in to an authoritarian regime.'" www.insidehighered.com/news/faculty...

Oh. 😳 Florida debates lifting some child labor laws to fill jobs vacated by undocumented immigrants

@labouruk.bsky.social Perhaps this is a more open site

@teamlabouruk.bsky.social thought I would respond to one of many emails the Labour Party send to members. Wanted to register deep disappointment with the latest savings policies. Bounceback said “the Team” cannot respond, advised writing to [email protected]. Bounceback says it can’t respond

@adelphigenetics see details at adelphigenetics.org has moved to Bluesky. Follow us and watch out for details of our free-to-attend annual conference on Population Genomic Screening to be held at The Royal Society on Thursday 23 October 2025

A lot of it is nice red brick!

Wow! The number of @bsky.app users just passed 33 MILLION!!! 👏 LETS DO THIS!!

Or ~21 NSFs Or ~5 USAIDs Or ~4 NIHs Or 1 Dept of education.

The Dow has dropped 1300 points over the last two days as Trump defiantly plows forward with tariffs against Mexico, Canada and China — America's most prominent trading partners.